| Literature DB >> 35940708 |
Xinyi Cao1, Wang Liao2, Shaokang Wang1.
Abstract
Dietary intervention via modifications of dietary pattern or supplementations of naturally derived bioactive compounds has been considered as an efficient approach in management of nutrition related chronic diseases. Food protein-derived bioactive peptide is representative of natural compounds which show the potential to prevent or mitigate nutrition related chronic diseases. In the past decades, substantial research has been conducted concentrating on the characterization, bioavailability, and activity assessment of bioactive peptides. Although various activities of bioactive peptides have been reported, the activity testes of most peptides were only conducted in cells and animal models. Some clinical trials of bioactive peptides were also reported but only limited to antihypertensive peptides, antidiabetic peptides and peptides modulating blood lipid profile. Hereby, clinical evidence of bioactive peptides in management of nutrition-related chronic diseases is summarized in this chapter, which aims at providing implications for the clinical studies of bioactive peptides in the future.Entities:
Keywords: Bioactive peptides; Cardiovascular diseases; Clinical trial; Dietary supplementation; Metabolic diseases
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Year: 2022 PMID: 35940708 DOI: 10.1016/bs.afnr.2022.04.004
Source DB: PubMed Journal: Adv Food Nutr Res ISSN: 1043-4526