| Literature DB >> 3593832 |
C M Warner, S O Gollnick, S B Goldbard.
Abstract
The preimplantation-embryo-development (Ped) gene influences the rate of cleavage division of preimplantation mouse embryos. The location of the Ped gene in the mouse major histocompatibility complex (MHC), the H-2 complex, has been inferred from the analysis of cleavage rates of embryos from mouse strains congenic at the H-2 complex. In this paper, formal genetic linkage studies were undertaken to evaluate linkage of the Ped gene to the H-2 complex. Co-segregation of Ped gene phenotype and H-2 haplotype was found in back-cross embryos. These data support the hypothesis that the Ped gene is linked to the H-2 complex.Entities:
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Year: 1987 PMID: 3593832 DOI: 10.1095/biolreprod36.3.606
Source DB: PubMed Journal: Biol Reprod ISSN: 0006-3363 Impact factor: 4.285