Literature DB >> 35936885

Transverse myelitis in a 26-year-old male with tuberculosis.

Edlira Harizi1, Kledisa Shemsi2, Erisa Kola3, Fjolla Hyseni4, Ina Kola5, Mohammad Abubaker Siddique6, Jafor Sadeque7, Arlind Decka8, Migena Dervishi9, Fareeha Nasir10, Livia Capi11, Ivan Ayala12, Ammy Shankar Ghosh13, Sanzida Sharmin Swarna14, Juna Musa15, Ilir Ahmetgjekaj16.   

Abstract

Acute transverse myelitis is an inflammatory condition covering the entire cross section of the spinal cord, spreading on two or more vertebral segments, without evidence of a compressive lesion. This shows clinically as an acute or subacute onset of paraparesis, lower limb paresthesia, sensory deficits, and impaired sphincter function. Mycobacterium tuberculosis is exceedingly rare cause of this inflammation, with a mechanism still not fully understood. The main etiologies are thought to be an abnormal activation of the immune system against the neuronal cells of the medulla, direct inoculation of the bacillus, and the toxic effect of the antitubercular medications on the spinal cord. We present the case of a 26-year-old male patient with acute symptoms of transverse myelitis and presence of miliary tuberculosis of the lungs. The purpose of this case report is to put the emphasis on the importance of distinguishing the characteristics of tubercular lesions on imaging modalities, especially on magnetic resonance imaging, in the differential diagnosis of tuberculosis as a rare but profoundly serious cause of acute transverse myelitis.
© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.

Entities:  

Keywords:  Acute transverse myelitis; Impaired sphincter function; Magnetic resonance; Miliary tuberculosis; Mycobacterium tuberculosis; Paraesthesia; Paraparesis

Year:  2022        PMID: 35936885      PMCID: PMC9352802          DOI: 10.1016/j.radcr.2022.06.091

Source DB:  PubMed          Journal:  Radiol Case Rep        ISSN: 1930-0433


  14 in total

1.  Cross-reactive antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in patients with Guillain-Barré or Miller Fisher syndrome.

Authors:  B C Jacobs; M P Hazenberg; P A van Doorn; H P Endtz; F G van der Meché
Journal:  J Infect Dis       Date:  1997-03       Impact factor: 5.226

2.  Acute transverse myelitis: MR characteristics.

Authors:  J M Murthy; J J Reddy; A K Meena; S Kaul
Journal:  Neurol India       Date:  1999-12       Impact factor: 2.117

3.  An Uncommon Cause of Longitudinally Extensive Transverse Myelitis.

Authors:  Catalina Coclitu; Athena Mergeani; Teodora Parvu; Octaviana Rusu; Andrei Ciobotaru; Ovidiu Bajenaru; Florina Antochi
Journal:  Maedica (Bucur)       Date:  2016-09

Review 4.  Immunopathogenesis of acute transverse myelitis.

Authors:  Douglas A Kerr; Harold Ayetey
Journal:  Curr Opin Neurol       Date:  2002-06       Impact factor: 5.710

5.  Encephalomyelitis-associated antimyelin autoreactivity induced by streptococcal exotoxins.

Authors:  P G Jorens; A VanderBorght; B Ceulemans; H P Van Bever; L L Bossaert; M Ieven; H Goossens; P M Parizel; H Van Dijk; J Raus; P Stinissen
Journal:  Neurology       Date:  2000-04-11       Impact factor: 9.910

Review 6.  Proposed diagnostic criteria and nosology of acute transverse myelitis.

Authors: 
Journal:  Neurology       Date:  2002-08-27       Impact factor: 9.910

Review 7.  Central nervous system tuberculosis: pathogenesis and clinical aspects.

Authors:  R Bryan Rock; Michael Olin; Cristina A Baker; Thomas W Molitor; Phillip K Peterson
Journal:  Clin Microbiol Rev       Date:  2008-04       Impact factor: 26.132

8.  CNS tuberculosis: a longitudinal analysis of epidemiological and clinical features.

Authors:  M Phypers; T Harris; C Power
Journal:  Int J Tuberc Lung Dis       Date:  2006-01       Impact factor: 2.373

Review 9.  An approach to the diagnosis of acute transverse myelitis.

Authors:  Anu Jacob; Brian G Weinshenker
Journal:  Semin Neurol       Date:  2008-02       Impact factor: 3.420

10.  A rare neurological complication of tuberculosis: Transverse myelitis.

Authors:  Alberto Ortega-Rosales; Nelson Delgado-Torres; Carlos Burneo-Rosales
Journal:  IDCases       Date:  2019-05-24
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