Senjie Dai1, Rongrong Fu2, Siya Jiang1, Yuanfang He3, Tongmin Huang1, Bin Zhou4, Hongjun Gong5. 1. The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. 2. The First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. 3. Basic Medical College, Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China. 4. Department of General Surgery, HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, Zhejiang, China. 5. Department of Anesthesiology, Ningbo Yinzhou No. 2 Hospital, 998 North Qianhe Road, Yinzhou District, Ningbo, 315100, Zhejiang, China. fqnjmjz@163.com.
Abstract
OBJECTIVE: The effectiveness of intraperitoneal local anesthesia (IPLA) has been confirmed in other fields, but its use in bariatric surgery remains debatable. This study aimed to evaluate the analgesic effect of IPLA in bariatric surgery. METHODS: PubMed, Web of Science, Embase, and the Cochrane Library were searched from inception to February 2022. All randomized controlled trials (RCTs) assessing IPLA's analgesic effect in bariatric surgery were included in this study. Pain-related indicators were the outcome. RESULTS: Ten RCTs with 979 patients were included. Postoperative pain scores were significantly lower in IPLA group. Subgroup analysis demonstrated that IPLA was associated with lower pain scores in 6 h and at 24 h compared to the control group, without significant differences at 8, 12, and 48 h. Meanwhile, IPLA reduced the dose of opioids taken postoperatively. Additionally, there were no differences in adverse events between the two groups. As far as the number of postoperative analgesics used and hospital stays were concerned, our results did not show statistical differences between the two groups. CONCLUSION: IPLA can reduce postoperative pain safely and effectively, particularly during the early postoperative stage.
OBJECTIVE: The effectiveness of intraperitoneal local anesthesia (IPLA) has been confirmed in other fields, but its use in bariatric surgery remains debatable. This study aimed to evaluate the analgesic effect of IPLA in bariatric surgery. METHODS: PubMed, Web of Science, Embase, and the Cochrane Library were searched from inception to February 2022. All randomized controlled trials (RCTs) assessing IPLA's analgesic effect in bariatric surgery were included in this study. Pain-related indicators were the outcome. RESULTS: Ten RCTs with 979 patients were included. Postoperative pain scores were significantly lower in IPLA group. Subgroup analysis demonstrated that IPLA was associated with lower pain scores in 6 h and at 24 h compared to the control group, without significant differences at 8, 12, and 48 h. Meanwhile, IPLA reduced the dose of opioids taken postoperatively. Additionally, there were no differences in adverse events between the two groups. As far as the number of postoperative analgesics used and hospital stays were concerned, our results did not show statistical differences between the two groups. CONCLUSION: IPLA can reduce postoperative pain safely and effectively, particularly during the early postoperative stage.
Authors: Toby N Weingarten; Juraj Sprung; Antolin Flores; Ana M Oviedo Baena; Darrell R Schroeder; David O Warner Journal: Obes Surg Date: 2011-09 Impact factor: 4.129
Authors: C E Nightingale; M P Margarson; E Shearer; J W Redman; D N Lucas; J M Cousins; W T A Fox; N J Kennedy; P J Venn; M Skues; D Gabbott; U Misra; J J Pandit; M T Popat; R Griffiths Journal: Anaesthesia Date: 2015-05-07 Impact factor: 6.955