Literature DB >> 35932457

EPAS1/HIF-2α: a key regulator for chronic hypoxia across species.

Esteban A Moya1.   

Abstract

Entities:  

Keywords:  EPAS1; high-altitude; hypoxia

Mesh:

Substances:

Year:  2022        PMID: 35932457      PMCID: PMC9481713          DOI: 10.1113/JP283554

Source DB:  PubMed          Journal:  J Physiol        ISSN: 0022-3751            Impact factor:   6.228


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  5 in total

1.  Genetic variation in HIF-2α attenuates ventilatory sensitivity and carotid body growth in chronic hypoxia in high-altitude deer mice.

Authors:  Catherine M Ivy; Jonathan P Velotta; Zachary A Cheviron; Graham R Scott
Journal:  J Physiol       Date:  2022-07-31       Impact factor: 6.228

2.  Physiological and genomic evidence that selection on the transcription factor Epas1 has altered cardiovascular function in high-altitude deer mice.

Authors:  Rena M Schweizer; Jonathan P Velotta; Catherine M Ivy; Matthew R Jones; Sarah M Muir; Gideon S Bradburd; Jay F Storz; Graham R Scott; Zachary A Cheviron
Journal:  PLoS Genet       Date:  2019-11-07       Impact factor: 5.917

Review 3.  Time Domains of Hypoxia Responses and -Omics Insights.

Authors:  James J Yu; Amy L Non; Erica C Heinrich; Wanjun Gu; Joe Alcock; Esteban A Moya; Elijah S Lawrence; Michael S Tift; Katie A O'Brien; Jay F Storz; Anthony V Signore; Jane I Khudyakov; William K Milsom; Sean M Wilson; Cynthia M Beall; Francisco C Villafuerte; Tsering Stobdan; Colleen G Julian; Lorna G Moore; Mark M Fuster; Jennifer A Stokes; Richard Milner; John B West; Jiao Zhang; John Y Shyy; Ainash Childebayeva; José Pablo Vázquez-Medina; Luu V Pham; Omar A Mesarwi; James E Hall; Zachary A Cheviron; Jeremy Sieker; Arlin B Blood; Jason X Yuan; Graham R Scott; Brinda K Rana; Paul J Ponganis; Atul Malhotra; Frank L Powell; Tatum S Simonson
Journal:  Front Physiol       Date:  2022-08-08       Impact factor: 4.755

4.  The adaptive benefit of evolved increases in hemoglobin-O2 affinity is contingent on tissue O2 diffusing capacity in high-altitude deer mice.

Authors:  Oliver H Wearing; Catherine M Ivy; Natalia Gutiérrez-Pinto; Jonathan P Velotta; Shane C Campbell-Staton; Chandrasekhar Natarajan; Zachary A Cheviron; Jay F Storz; Graham R Scott
Journal:  BMC Biol       Date:  2021-06-22       Impact factor: 7.431

5.  Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.

Authors:  Emma J Hodson; Lynn G Nicholls; Philip J Turner; Ronan Llyr; James W Fielding; Gillian Douglas; Indrika Ratnayaka; Peter A Robbins; Christopher W Pugh; Keith J Buckler; Peter J Ratcliffe; Tammie Bishop
Journal:  J Physiol       Date:  2015-10-06       Impact factor: 5.182

  5 in total

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