Literature DB >> 35931821

R-2-HG assists IDH1-mutant solid tumors by promoting angiogenesis.

Nuray Bögürcü-Seidel1, Gabriele Bergers2,3.   

Abstract

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Year:  2022        PMID： 35931821      PMCID： PMC9437032          DOI： 10.1038/s41422-022-00708-9

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   46.297


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  9 in total

1.  Role of PFKFB3-driven glycolysis in vessel sprouting.

Authors:  Katrien De Bock; Maria Georgiadou; Sandra Schoors; Anna Kuchnio; Brian W Wong; Anna Rita Cantelmo; Annelies Quaegebeur; Bart Ghesquière; Sandra Cauwenberghs; Guy Eelen; Li-Kun Phng; Inge Betz; Bieke Tembuyser; Katleen Brepoels; Jonathan Welti; Ilse Geudens; Inmaculada Segura; Bert Cruys; Franscesco Bifari; Ilaria Decimo; Raquel Blanco; Sabine Wyns; Jeroen Vangindertael; Susana Rocha; Russel T Collins; Sebastian Munck; Dirk Daelemans; Hiromi Imamura; Roland Devlieger; Mark Rider; Paul P Van Veldhoven; Frans Schuit; Ramon Bartrons; Johan Hofkens; Peter Fraisl; Sucheta Telang; Ralph J Deberardinis; Luc Schoonjans; Stefan Vinckier; Jason Chesney; Holger Gerhardt; Mieke Dewerchin; Peter Carmeliet
Journal:  Cell       Date:  2013-08-01       Impact factor: 41.582

2.  Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate.

Authors:  Lukas Bunse; Stefan Pusch; Theresa Bunse; Felix Sahm; Khwab Sanghvi; Mirco Friedrich; Dalia Alansary; Jana K Sonner; Edward Green; Katrin Deumelandt; Michael Kilian; Cyril Neftel; Stefanie Uhlig; Tobias Kessler; Anna von Landenberg; Anna S Berghoff; Kelly Marsh; Mya Steadman; Dongwei Zhu; Brandon Nicolay; Benedikt Wiestler; Michael O Breckwoldt; Ruslan Al-Ali; Simone Karcher-Bausch; Matthias Bozza; Iris Oezen; Magdalena Kramer; Jochen Meyer; Antje Habel; Jessica Eisel; Gernot Poschet; Michael Weller; Matthias Preusser; Minou Nadji-Ohl; Niklas Thon; Michael C Burger; Patrick N Harter; Miriam Ratliff; Richard Harbottle; Axel Benner; Daniel Schrimpf; Jürgen Okun; Christel Herold-Mende; Sevin Turcan; Stefan Kaulfuss; Holger Hess-Stumpp; Karen Bieback; Daniel P Cahill; Karl H Plate; Daniel Hänggi; Marion Dorsch; Mario L Suvà; Barbara A Niemeyer; Andreas von Deimling; Wolfgang Wick; Michael Platten
Journal:  Nat Med       Date:  2018-07-09       Impact factor: 53.440

3.  Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas.

Authors:  Mirco Friedrich; Roman Sankowski; Lukas Bunse; Marco Prinz; Michael Platten; Michael Kilian; Edward Green; Carina Ramallo Guevara; Stefan Pusch; Gernot Poschet; Khwab Sanghvi; Markus Hahn; Theresa Bunse; Philipp Münch; Hagen M Gegner; Jana K Sonner; Anna von Landenberg; Frederik Cichon; Katrin Aslan; Tim Trobisch; Lucas Schirmer; Denis Abu-Sammour; Tobias Kessler; Miriam Ratliff; Daniel Schrimpf; Felix Sahm; Carsten Hopf; Dieter H Heiland; Oliver Schnell; Jürgen Beck; Chotima Böttcher; Camila Fernandez-Zapata; Josef Priller; Sabine Heiland; Ilona Gutcher; Francisco J Quintana; Andreas von Deimling; Wolfgang Wick
Journal:  Nat Cancer       Date:  2021-05-24

4.  SLC1A1-mediated cellular and mitochondrial influx of R-2-hydroxyglutarate in vascular endothelial cells promotes tumor angiogenesis in IDH1-mutant solid tumors.

Authors:  Xiaomin Wang; Ziqi Chen; Jun Xu; Shuai Tang; Nan An; Lei Jiang; Yixiang Zhang; Shaoying Zhang; Qingli Zhang; Yanyan Shen; Shijie Chen; Xiaojing Lan; Ting Wang; Linhui Zhai; Siyuwei Cao; Siqi Guo; Yingluo Liu; Aiwei Bi; Yuehong Chen; Xiameng Gai; Yichen Duan; Ying Zheng; Yixian Fu; Yize Li; Liang Yuan; Linjiang Tong; Kun Mo; Mingcheng Wang; Shu-Hai Lin; Minjia Tan; Cheng Luo; Yi Chen; Jia Liu; Qiansen Zhang; Leping Li; Min Huang
Journal:  Cell Res       Date:  2022-04-22       Impact factor: 46.297

5.  Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Authors:  Lenny Dang; David W White; Stefan Gross; Bryson D Bennett; Mark A Bittinger; Edward M Driggers; Valeria R Fantin; Hyun Gyung Jang; Shengfang Jin; Marie C Keenan; Kevin M Marks; Robert M Prins; Patrick S Ward; Katharine E Yen; Linda M Liau; Joshua D Rabinowitz; Lewis C Cantley; Craig B Thompson; Matthew G Vander Heiden; Shinsan M Su
Journal:  Nature       Date:  2009-12-10       Impact factor: 49.962

6.  Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study.

Authors:  Ghassan K Abou-Alfa; Teresa Macarulla; Milind M Javle; Robin K Kelley; Sam J Lubner; Jorge Adeva; James M Cleary; Daniel V Catenacci; Mitesh J Borad; John Bridgewater; William P Harris; Adrian G Murphy; Do-Youn Oh; Jonathan Whisenant; Maeve A Lowery; Lipika Goyal; Rachna T Shroff; Anthony B El-Khoueiry; Bin Fan; Bin Wu; Christina X Chamberlain; Liewen Jiang; Camelia Gliser; Shuchi S Pandya; Juan W Valle; Andrew X Zhu
Journal:  Lancet Oncol       Date:  2020-05-13       Impact factor: 41.316

7.  The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.

Authors:  Patrick S Ward; Jay Patel; David R Wise; Omar Abdel-Wahab; Bryson D Bennett; Hilary A Coller; Justin R Cross; Valeria R Fantin; Cyrus V Hedvat; Alexander E Perl; Joshua D Rabinowitz; Martin Carroll; Shinsan M Su; Kim A Sharp; Ross L Levine; Craig B Thompson
Journal:  Cancer Cell       Date:  2010-02-18       Impact factor: 38.585

Review 8.  The Roles of 2-Hydroxyglutarate.

Authors:  Xin Du; Hai Hu
Journal:  Front Cell Dev Biol       Date:  2021-03-26

9.  Control of endothelial quiescence by FOXO-regulated metabolites.

Authors:  Jorge Andrade; Chenyue Shi; Ana S H Costa; Jeongwoon Choi; Jaeryung Kim; Anuradha Doddaballapur; Toshiya Sugino; Yu Ting Ong; Marco Castro; Barbara Zimmermann; Manuel Kaulich; Stefan Guenther; Kerstin Wilhelm; Yoshiaki Kubota; Thomas Braun; Gou Young Koh; Ana Rita Grosso; Christian Frezza; Michael Potente
Journal:  Nat Cell Biol       Date:  2021-04-01       Impact factor: 28.213
  9 in total

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