Literature DB >> 35928510

Increased motivation for and use of digital services in heart failure patients participating in a telerehabilitation program: a randomized controlled trial.

Helle Spindler1, Anne-Kirstine Dyrvig2, Cathrine Skov Schacksen3, Danny Anthonimuthu3, Lars Frost4,5, Josefine Dam Gade3, Sissel Højsted Kronborg3, Kiomars Mahboubi6, Jens Refsgaard7, Birthe Dinesen3, Malene Hollingdal7, Lars Kayser8.   

Abstract

Background: eHealth literacy (eHL) may be an important factor in the adoption of telerehabilitation. However, little is known about how telerehabilitation affects patients' eHL. The current study evaluated changes over time in eHL for heart failure (HF) patients in a telerehabilitation program (the Future Patient Program) compared to a traditional rehabilitation program.
Methods: As part of a randomized controlled trial comparing telerehabilitation with traditional rehabilitation, 137 HF patients completed the eHealth Literacy Questionnaire (eHLQ) at 6 and 12 months of their respective rehabilitation programs.
Results: At 6 months, the telerehabilitation group indicated higher levels of 'using technology to process health information' and 'motivated to engage with digital services'. This difference was consistent over time, and we found no other differences between groups or over time with regard to eHL. Conclusions: Providing a digital toolbox for processing health information to HF patients may aid in increasing their eHL, motivation, and ability to engage with digital services in HF patients. Especially, if the technology is designed to support patient needs in terms of the educational content of the program. Preferably technology should be provided early on in the rehabilitation process to ensure optimal outcome. Trial Registration: The study was registered in ClinicalTrials.gov (NCT03388918). 2022 mHealth. All rights reserved.

Entities:  

Keywords:  Heart failure (HF); e-health literacy; patient education; telerehabilitation

Year:  2022        PMID: 35928510      PMCID: PMC9343969          DOI: 10.21037/mhealth-21-56

Source DB:  PubMed          Journal:  Mhealth        ISSN: 2306-9740


Introduction

Heart failure (HF) is a chronic heart condition diagnosed in more than 37 million people worldwide (1). HF is the cause of a substantial proportion of the 31% of all fatalities worldwide (corresponding to 17.9 million people in 2016) ascribed to cardiovascular disease (2). Overall, the prevalence of HF is rising, in part through increasingly unhealthy lifestyles among the elderly. The rising prevalence of HF has led to a corresponding increase in the burden on healthcare systems (3). To facilitate the rehabilitation of people with HF, the European Society of Cardiology recommends provision of education and support in self-care skills in order to impede or prevent a worsening of their condition, e.g., more exercise, improving diet, taking prescribed medicine, weighing themselves daily, and knowing when to contact their healthcare provider. Inclusion of these recommendations in rehabilitation programs, both at healthcare centers and at home, has been shown to reduce readmission rates (4). Despite the clear-cut advantage of rehabilitation, one study (5) found a 56% drop-out rate during exercised-based rehabilitation programs, even with a supportive environment that included multiple contacts and educational methods suggesting that non-adherence is the main challenge to the rehabilitation programs. A systematic review found that comorbidities, advanced age, and accessibility were the main factors resulting in low participation in and adherence to cardiac rehabilitation programs (6). This suggests that diverse groups of people initially engaging in rehabilitation need alternative support and pathways, especially when attendance at the healthcare centres is not an option or not perceived as a necessity for them. A possible solution to the non-adherence problem is telerehabilitation, defined as the provision of rehabilitation via information and communication technologies over distance (7). To advance the telerehabilitation field, we developed a cardiac rehabilitation web portal, called the ‘HeartPortal’, which aims to increase the quality of life of people with HF and to provide education on self-monitoring so that patients can detect worsening of their symptoms, react by contacting healthcare professionals, and thereby avoid rehospitalization (8). With telerehabilitation technologies, the rehabilitation activities may be targeted to the patient’s lifestyle and self-management needs using digital channels (9). Moreover, providing patients with telerehabilitation technologies aligns well with the general development of digitalized public service provision, which is the case in Denmark (10). In Denmark, 88% of citizens have searched for information, downloaded forms or submitted information to public authorities via online portals (11). In addition, 82% of Danes consider the use of welfare technology a “good” option in future. This suggests that in addition to encouraging patients to become more health literate (i.e., be motivated and able to gain access to, understand, and use health information to promote and maintain good health) (12,13), it is also necessary that they acquire electronic health literacy, also known as eHealth literacy (eHL) or digital health literacy, in order to access public digital health services. The literature on eHL employs several definitions emphasizing different frameworks and scales associated with each conceptualisation of eHL. The eHealth Literacy Scale (eHEALS) is a measure of the users’ competence to engage with digital health services (14). Although this scale evaluates information-seeking behaviour on the internet in relation to health, it falls short as an evaluation tool for assessing the suitability of a given design solution to the specific user’s needs and capabilities. To address this issue, Kayser et al. developed the eHealth Literacy Questionnaire (eHLQ) based on the eHL framework (eHLF) (15), in order to measure users’ knowledge, skills, perception, and experiences in relation to digital health services and health technologies in a singular measure (15). The resulting eHLQ is a multidimensional measure of the dimensions in the eHL framework, which may be of relevance for evaluating innovative telerehabilitation technologies (15). The HeartPortal was designed through a participatory design process, involving HF patients, their relatives, healthcare professionals, and researchers as an interactive portal that included communication of information in the form of text, video, and sound in order to match patients’ preferences (8). As such, the HeartPortal was in part designed to support and develop patient’s eHL, by providing relevant information in a digital format that matched the desires and abilities of the users. The design and usability of the HeartPortal was evaluated by Joensson et al. (16), who found that the HeartPortal was easy to navigate and understand. Furthermore, the study indicated that the usability of the HeartPortal motivated users to adhere to the rehabilitation program and to learn more about their own disease using eHL (16). To our knowledge, few studies have investigated eHL within the framework of a telerehabilitation program for patients with ischemic heart disease or HF (17-19). In the Teledialogue study by Melholt et al. (19), a significant change over time in self-reported eHL was found when testing a web cardiac portal over three months. The aim of the current study was to explore changes in eHL from 6 to 12 months, comparing a telerehabilitation group (TR) and a control group (CT) as part of the Future Patient Telerehabilitation (FPT) Program for people with heart failure. We present the following article in accordance with the CONSORT reporting checklist (available at https://mhealth.amegroups.com/article/view/10.21037/mhealth-21-56/rc).

Methods

Study design and data collection

This study is a sub-study of the FPT Program which was designed as a randomized controlled trial using 1:1 allocation of participants (8). The sample size for this sub-study was contingent upon the main study outcomes (15). All participants completed the eHLQ after 6 and 12 months of participation. Each patient received at least two reminders to complete and return the questionnaire. The reminders were messaged via the HeartPortal, e-mail, phone, voicemail, or text. All data from the questionnaires were entered into and stored in REDCap (20).

Participants and inclusion criteria

Participants in the study were people diagnosed with HF according to the New York Heart Association (NYHA) class I–IV (21). The recruitment of participants was performed by a project nurse, who contacted patients at four cardiology wards at public hospitals in Randers, Silkeborg, Skive, and Viborg, all located in the central region of Jutland, Denmark. Inclusion criteria were 18 years of age or above, heart-failure-related hospitalization within the previous two weeks, knowledge of basic Danish language, and access to a stable internet connection at home. No more than 20% of the total sample could be categorized as NYHA class I, and patients with a pacemaker were also eligible. Exclusion criteria were not being able to understand Danish, an active psychiatric condition other than depression or anxiety related to cardiac or other chronic illness, and coronary revascularization and/or open-heart surgery within the previous three months. Also excluded were patients whose medical records indicated previous neurological, musculoskeletal or cognitive disabilities. In addition, four participants with more than 50% missing values on a specific subscale of the eHLQ were excluded from analysis. After inclusion, all patients were randomly allocated to either the TR or the CT group. This process is illustrated in the CONSORT diagram below (), including reasons for dropouts at each step.
Figure 1

CONSORT diagram for the eHealth literacy sub-study in the Future Patient Telerehabilitation Program.

CONSORT diagram for the eHealth literacy sub-study in the Future Patient Telerehabilitation Program.

Intervention

The FPT Program follows three phases over a 12-month period (see ). The phases are: (I) HF education and titration of medicine; (II) telerehabilitation in a healthcare center; and (III) everyday life with telerehabilitation. The TR group of patients with HF were provided with self-tracking devices and an iPad to be used to access the HeartPortal, which acted as a digital toolbox for this group. The digital toolbox was used (I) to obtain educational material on life with HF; (II) to contact health professionals in hospitals digitally; (III) to monitor their personal data, such as blood pressure, heart rate, weight, step, respiration, and sleep; (IV) to create a rehabilitation plan and set personal goals; and (V) to monitor Patient Reported Outcomes. As such, the HeartPortal provided information and opportunities for patients to develop and strengthen their eHL. This was in line with our use of the self-determination theory (STD) (22) to inform our design process in order to optimize patient motivation (8,16). The SDT states that in order to obtain motivation three basic needs must be supported: (I) autonomy (acting in accordance with one’s internal values); (II) competency (having the necessary skills and knowledge to carry out desired behaviour); and (III) relatedness (feeling supported by a social network). Hence improving skills relevant to eHL is also important for patient motivation.
Figure 2

Phases in the Future Patient Telerehabilitation Program. The figure was Originally published in (8) JMIR Research Protocols (http://www.researchprotocols.org), 19.09.2019 ©Birthe Dinesen, Lars Dittmann, Josefine Dam Gade, Cecilia Klitgaard Jørgensen, Malene Hollingdal, Soeren Leth, Camilla Melholt, Helle Spindler, Jens Refsgaard.

Phases in the Future Patient Telerehabilitation Program. The figure was Originally published in (8) JMIR Research Protocols (http://www.researchprotocols.org), 19.09.2019 ©Birthe Dinesen, Lars Dittmann, Josefine Dam Gade, Cecilia Klitgaard Jørgensen, Malene Hollingdal, Soeren Leth, Camilla Melholt, Helle Spindler, Jens Refsgaard.

Outcomes

The eHLQ (15) was used to evaluate eHL. The eHLQ is a 35-item questionnaire consisting of seven scales (see ). Each item is scored using a four-point Likert scale response format of strongly disagree [1] to strongly agree [4], and item content is based on the eHL framework (15). The seven scales can be combined into three dimensions (see ); users’ knowledge and skills, elements comprising eHL (scales 1–3), trust and motivation (scales 4–5) and experience (scales 6–7). The eHLQ is considered user-friendly and suitable for use in both non-clinical and clinical populations, as well as for people with low literacy. As described previously, this questionnaire was chosen because it is multidimensional and assesses key user characteristics (e.g., the interaction between digital services and user, as well as the user experience). Moreover, the eHLQ has shown good psychometric properties in a Danish context (15). In the current project, we planned to include the eHLQ at 0, 6, and 12 months, however, due to an unfortunate error, the eHLQ was not included at 0 month, but only distributed to all participants via e-mail at 6 and 12 months. Consequently, we have no data for eHLQ at 0 month.
Table 1

Overview of eHLQ scales and dimensions

eHLQ scaleNo of itemsDimensions
1. Using technology to process health information5The user’s individual competence or eHealth literacy
2. Understanding of health concepts and language5
3. Ability to actively engage with digital services5The interaction between the user and the digital services
4. Feeling safe and in control5
5. Motivated to engage with digital services5
6. Access to digital services that work6The user’s experience with digital systems or services
7. Digital services that suit individual needs4

eHLQ, eHealth Literacy Questionnaire.

eHLQ, eHealth Literacy Questionnaire.

Ethics

The FPT Project was approved by the Regional Ethics Committee for North Denmark (N-20160055) and by the Danish Data Protection Agency. The study was registered in ClinicalTrials.gov (NCT03388918). The study was carried out in accordance with the Helsinki Declaration (as revised in 2013), and all participants signed an informed consent form prior to enrolment in the study.

Statistical analysis

Mean substitution was used when at least 50% of data was available on a specific measure for a participant (23). Data was examined for issues of non-normality using the Shapiro-Wilk test and by inspection of normality plots. As this process revealed potential problems with normality, we chose to accommodate for issues of non-normality by using a robust analysis in all subsequent analyses, i.e., a boot-strapping procedure using 1,000 samples. This procedure was chosen over non-parametric tests because it would enhance clinical interpretation of results. Baseline characteristics were compared using χ2, t-test or Fisher’s exact test as appropriate. Since the eHLQ was not used at baseline, we had data only for 6 and 12 months. As a consequence, we treated our 6-months data as a baseline proxy. Due to the use of robust analysis to accommodate for non-normality, we did not use analysis of variance (ANOVA), but conducted analyses in three steps. Initially, we compared our two groups on 6 months scores on the eHLQ using a robust two-tailed independent t-test with a bootstrapping procedure of 1,000 samples accompanied by estimates of effect sizes (ES) including a 95% CI. We then evaluated changes over time in each group by conducting a robust two-tailed paired samples t-test for each of the 7 scales on the eHLQ, again using a bootstrapping procedure with 1,000 samples. Based on these analyses, we also calculated ES with a 95% CI in order to aid clinical interpretation of our results. Finally, to compare eHLQ changes in groups over time, we first transformed our 6- and 12-month data sets into change scores for each scale, and then conducted a robust two-tailed independent t-test for each scale. ES with a 95% CI were also calculated based on these analyses. Although we conducted several sets of analyses, we opted for reporting all analyses rather than conducting a Bonferroni correction, significance level of 0.05 was chosen for all analyses, and all analyses were carried out using SPSS version 26 (24).

Results

Of 353 patients assessed for eligibility, 140 were enrolled in the FPT Project, of which 137 were included in this sub-study. Excluded participants tended to be <50 years of age, male, and more likely to have an educational status as skilled worker (see ).
Table 2

Baseline clinical and demographic characteristics of the telerehabilitation and control groups

Telerehabilitation group (N=67)Control group (N=70)P
Clinical parameters
   Weight (kg), mean (SD)85.3 (20.4)90.03 (20.9)0.19
   Systolic blood pressure (mmHg), mean (SD)124.4 (17.7)129.2 (18.6)0.10
   Diastolic blood pressure (mmHg), mean (SD)78.9 (10.9)81.9 (12.2)0.13
   Heart rate(beats/minute), mean (SD)78.7 (17.8)75.1 (16.0)0.22
   Ejection fraction (%), mean (SD)31.8 (8.5)32.1 (9.4)0.83
   NYHA class, n [%]0.37
    I10 [15]15 [21]
    II42 [63]44 [63]
    III13 [19]11 [16]
    IV2 [3]0 [0]
Demographic parameters
   Age, mean (SD)61.73 (10.75)61.36 (11.46)0.84
   Male gender, n [%]51 [76]54 [77]0.89
   Civil status, n [%] 0.46
    Single24 [36]20 [28]
    Married/living with a partner43 [64]50 [71]
   Education, n [%]0.41
    Primary school4 [6]1 [1]
    Unskilled 16 [24]13 [19]
    Skilled worker30 [45]38 [54]
    High school5 [7]5 [7]
    Bachelor degree9 [13]7 [10]
    Master degree2 [3]6 [9]
    PhD+1 [1]0 [0]
   Work status, n [%]0.28
    Unemployed0 [0]1 [1]
    Sick leave19 [28]26 [37]
    Works less than 20 hours per week5 [7]1 [1]
    Works 20–36 hours per week2 [3]1 [1]
    Works full-time 37 hours per week9 [13]8 [11]
    Retired32 [48]33 [47]
Analyses of baseline characteristics (χ2, t-test or Fisher’s exact test) showed no significant differences between our TR and our CT groups on any of our baseline sociodemographic and clinical variables (see ). As our sample is relatively small, we therefore chose not to adjust for any of our baseline characteristics in the subsequent analyses. At 6 months, robust independent t-test indicated significant differences between our TR and our CT group with regards to subscale 1, ‘Using technology to process health information’ in the skills and knowledge or e-health literacy dimension, as our TR group scored significantly higher than our CT group with an estimated ES based on our bootstrap procedure of 0.42; indicating a difference of a small to medium ES between the two groups. A similar result emerged for subscale 5, ‘Motivation to engage with digital services’ in the trust and motivation dimension, with an ES of 0.59, i.e., a medium ES between groups, with our TR group scoring higher than our CT group. As we have no true baseline measure from eHLQ, it is uncertain whether these differences emerged from 0 to 6 months, or whether they were present already at baseline. In the next step, we examined changes on the eHLQ subscales from 6–12 months within each group. The robust paired samples t-tests indicated that neither group experienced significant changes from 6 to 12 months on any of the eHLQ subscales. These results were supported by the fact that ES for changes over time failed to reach the threshold for a small effect (see ).
Table 3

Scores and change score on the eHLQ at 6 and 12 months for the telerehabilitation group and control group

Scale6 months (mean ±SD)12 months (mean ±SD)Change score: 6 vs. 12 months (mean ±SD)PCohen’s d (95% CI)
1. Using technology to process health information
   Telerehabilitation (n=51)(2.98±0.66)(3.01±0.60)(0.03±0.65)0.7510.05 (−0.23 to 0.32)
   Control (n=46) (2.71±0.65)(2.78±0.70)(0.08±0.48)0.2720.16 (−0.13 to 0.45)
   TR (n=51) vs. CT (N=46) 6 months0.0430.42 (0.02 to 0.83)
   TR (n=51) vs. CT (N=46) change scores0.694−0.08 (−0.48 to 0.32)
2. Understanding of health concepts and language
   Telerehabilitation (n=51)(3.21±0.43)(3.27±0.44)(0.06±0.50)0.4110.12 (−0.16 to 0.39)
   Control (n=46) (3.08±0.43)(3.1±0.51)(0.02±0.37)0.7220.05 (−0.24 to 0.34)
   TR (n=51) vs. CT (N=46) 6 months0.1430.31 (−0.09 to 0.71)
   TR (n=51) vs. CT (N=46) change scores0.6440.09 (−0.31 to 0.49)
3. Ability to actively engage with digital services
   Telerehabilitation (n=51)(3.11±0.70)(3.2±0.56)(0.11±0.77)0.3210.14 (−0.14 to 0.42)
   Control (n=46) (2.87±0.66)(2.90±0.71)(0.03±0.50)0.7420.05 (−0.24 to 0.34)
   TR (n=51) vs. CT (N=46) 6 months0.0830.36 (−0.04 to 0.77)
   TR (n=51) vs. CT (N=46) change scores0.5340.13 (−0.27 to 0.52)
4. Feel safe and in control
   Telerehabilitation (n=51)(3.22±0.42)(3.27±0.47)(0.05±0.57)0.5510.09 (−0.19 to 0.36)
   Control (n=46) (3.17±0.46)(3.22±0.51)(0.05±0.40)0.3820.13 (−0.16 to 0.42)
   TR (n=51) vs. CT (N=46) 6 months0.573−0.12 (−0.28 to 0.51)
   TR (n=51) vs. CT (N=46) change scores0.9840.00 (−0.40 to 0.39)
5. Motivated to engage with digital services
   Telerehabilitation (n=51)(3.12±0.54)(3.15±0.50)(0.03±0.64)0.7610.04 (−0.23 to 0.32)
   Control (n=46) (2.79±0.60)(2.86±0.61)(0.07±0.48)0.3020.14 (−0.15 to 0.43)
   TR (n=51) vs. CT (N=46) 6 months0.0030.59 (0.18 to 0.99)
   TR (n=51) vs. CT (N=46) change scores0.734−0.07 (−0.47 to 0.33)
6. Access to digital services that work
   Telerehabilitation (n=51)(3.07±0.50)(3.14±0.37)(0.07±0.60)0.4010.12 (−0.16 to 0.39)
   Control (n=46)(2.90±0.54)(2.97±0.54)(0.06±0.36)0.2420.18 (−0.12 to 0.46)
   TR (n=51) vs. CT (N=46) 6 months0.1230.32 (−0.08 to 0.72)
   TR (n=51) vs. CT (N=46) change scores0.9640.01 (−0.39 to 0.41)
7. Digital services that suit individual needs
   Telerehabilitation (n=51)(2.89±0.61)(2.98±0.54)(0.09±0.81)0.4610.11 (−0.17 to 0.38)
   Control (n=46)(2.66±0.68)(2.78±0.62)(0.11±0.45)0.1120.25 (−0.04 to 0.54)
   TR (n=51) vs. CT (N=46) 6 months0.0930.36 (−0.05 to 0.76)
   TR (n=51) vs. CT (N=46) change scores0.844−0.04 (−0.44 to 0.36)

1, comparison of group scores in the TR group at 6 and 12 months; 2, comparison of group scores in the CT group at 6 and 12 months; 3, comparison of 6 months scores across the TR and CT group; 4, comparison of change scores (6–12 months) across the TR and CT group. eHLQ, eHealth Literacy Questionnaire; TR, telerehabilitation group; CT, control group.

1, comparison of group scores in the TR group at 6 and 12 months; 2, comparison of group scores in the CT group at 6 and 12 months; 3, comparison of 6 months scores across the TR and CT group; 4, comparison of change scores (6–12 months) across the TR and CT group. eHLQ, eHealth Literacy Questionnaire; TR, telerehabilitation group; CT, control group. In a final set of analyses, we evaluated differences in patterns of change across our two groups by calculating changes in the scores for each group based on the measures for 6 and 12 months, respectively (see ). Based on these change scores on each of the 7 scales of the eHLQ, we conducted robust independent t-tests and found no differences in changes over time across our two groups, suggesting that any small variations in eHLQ scores over time were comparable across our two groups. Taken together, our analyses indicate that eHLQ changed very little from 6 to 12 months of the FPT program, and that the variations over time within each group were comparable.

Discussion

The current study examined changes in eHL as measured by the EHLQ from 6 months to 12 months, comparing a TR group and a CT group in the FPT program. Our results indicate that our groups differed on the eHLQ scales ‘Using technology to process health information’ (on the dimension knowledge and skills, which incorporate eHL) and ‘Motivated to engage with digital services’ (on the trust and motivation dimension) 6 months into our program. Unfortunately, due to an error, we have no baseline measures from the EHLQ that could help determine whether these differences emerged from 0 to 6 months, or were already present at baseline. Despite the lack of baseline measures, it is likely that the TR group indicated more use of digital technology to process health information as well as higher motivation to engage with digital services at 6 months, as they had been engaged in telerehabilitation since baseline and were therefore more familiar with digital health services. Further analyses indicate that from 6 to 12 months, no significant changes in any eHL measure were found in either group, a pattern that was consistent across groups. These results were supported by bootstrapped estimates of ES, which showed that none of the comparisons crossed the threshold for a small ES, except for the 6 months’ differences between groups on the two scales mentioned above. Taken together, these findings suggest that the differences between groups identified at 6 months were consistent over time. The fact that our TR group felt more motivated to use digital services indicate that the FPT program may have successfully motivated patients to use the digital telerehabilitation platform, as they engaged in using relevant digital health services. As such, these findings supports the notion that when designing telerehabilitation programs, it is important to create digital health services that motivate and match the needs of the users in order to give them a positive user experience (25). Simply digitalizing existing services is not sufficient for successful engagement in telerehabilitation, motivation is essential for digital practices becoming a routine part of the patients’ everyday lives, in turn improving disease management and self-care. The current results from the FPT program align with the findings in a review by Oudkerk Pool et al., who concluded that digital cardiac patient education increases patient knowledge, improves their quality of life, and increases cardiac patients’ level of satisfaction with digital platforms (26). Furthermore, we found that our TR group used technology to process health information more frequently than did our CT group (see ), which may reflect that the TR group became more accustomed to using digital services and made it part of their daily lives. A study by Albert et al. found that HF patients with higher health literacy and previous/current device use history tended to be more comfortable in using the devices (27), and Joensson et al. found that patients who received feedback regarding their health status and rehabilitation activities used this information to further improve their health condition (16). As such, patients who have become accustomed to using digital services increase their benefit and competency when using the digital services, suggesting that providing patients with opportunities to learn how to use digital services may increase patients’ benefits. Overall, both our groups scored high on e-health literacy measures, indicating that eHL such as skills and knowledge, trust in, and motivation to use, as well as experiences with digital health services generally was high in our sample. This may reflect that the Danish health care services are highly digitalized, and Danes have become very familiar with digital public services (10,11). As such, e-health literacy may already be high among the Danish population in general, and the changes identified in this study may reflect patients adapting existing eHL to their acute needs and specific health situation and not a specific development of or changes in eHL in general. In addition, our results indicate that once the formal rehabilitation program ends, there is little chance of further changes in aspects of eHL. This may reflect that interventions aimed at increasing eHL and associated skills and knowledge, building trust and motivation, and providing opportunities for using digital health services should preferably be provided early on in any form of rehabilitation program, and care should be taken to identify and support patients, who may find it difficult to adapt to digital health services. This is especially pertinent in so far as increasing eHL, enabling patients to engage with digital health services has become even more important in the wake of the COVID-19 pandemic, which required a rapid and comprehensive digitalization of health care services generally. Overall, the findings from this study indicate that exposure to and familiarization with digital health services may increase patients’ perception of the usability of web-based interventions, which is important for the user’s motivation and for creating and ensuring their adherence to digital tools. There is limited research on eHL in telerehabilitation programs for patients with ischemic heart disease or HF (17-19), and we have not identified other studies that have investigated the eHL perspectives in patients with HF doing TR. However, studies in other patient populations support the benefit of using telerehabilitation programs. A recent study investigating the use of an app-based intervention in prostate cancer patients showed that the patients found the app to be equivalent or easier to use compared to the traditional pen and paper approach (28). Another study that examined eHL among patients with chronic obstructive pulmonary disease (COPD) found a statistically significant association between greater knowledge of COPD and higher eHL together with the use of web-based health resources (29). Taken together, the current findings and previous studies support the importance of incorporating educational elements in rehabilitation programs, as is done in the HeartPortal. This study was carried out in a Danish context. Hence, there might be differences in the patient population and organization of the healthcare systems when seen in a global context. As such, results may not be directly transferable to other health care systems and care should be taken to adapt the FPT program and HeartPortal to the specific patient population and health care system in which it is implemented, in order to ensure that specific needs are met as suggested by the SDT. In addition, due to an error, we did not include our eHL measure at 0 month, but only at 6 and 12 months. This limits the interpretability of current results, as it is unclear whether any differences were present at baseline. Furthermore, we only examined changes over a 6 months period, and future studies should examine the effect of online interventions in relation to eHL long term, as well as ensure that a baseline measurement on eHL is included in addition to the measures used here. In addition, although the multidimensional nature of our eHealth measure in some aspects is a clear strength of this study, it also requires that analyses must be carried out on 7 different parameters simultaneously, increasing the risk of serendipitous results. It is therefore paramount that future studies address these findings examining whether they can be replicated in other countries, larger samples, and even in other patient groups.

Conclusions

When people with HF are provided with a digital toolbox to process their health information, they increase their skills and knowledge regarding their disease, and become more motivated to engage with digital services, compared to patients who have not been provided with relevant technology. These results indicate that providing patients with HF with access to technology, i.e., a telerehabilitation program, early on, may increase their motivation to use digital services as part of their rehabilitation. The article’s supplementary files as
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4.  2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.

Authors:  Piotr Ponikowski; Adriaan A Voors; Stefan D Anker; Héctor Bueno; John G F Cleland; Andrew J S Coats; Volkmar Falk; José Ramón González-Juanatey; Veli-Pekka Harjola; Ewa A Jankowska; Mariell Jessup; Cecilia Linde; Petros Nihoyannopoulos; John T Parissis; Burkert Pieske; Jillian P Riley; Giuseppe M C Rosano; Luis M Ruilope; Frank Ruschitzka; Frans H Rutten; Peter van der Meer
Journal:  Eur J Heart Fail       Date:  2016-05-20       Impact factor: 15.534

5.  Web-based Health Information Seeking and eHealth Literacy among Patients Living with Chronic Obstructive Pulmonary Disease (COPD).

Authors:  Michael L Stellefson; Jonathan J Shuster; Beth H Chaney; Samantha R Paige; Julia M Alber; J Don Chaney; P S Sriram
Journal:  Health Commun       Date:  2017-09-05

Review 6.  Review of Digitalized Patient Education in Cardiology: A Future Ahead?

Authors:  Marinka D Oudkerk Pool; Jean-Luc Q Hooglugt; Marlies P Schijven; Barbara J M Mulder; Berto J Bouma; Robbert J de Winter; Yigal Pinto; Michiel M Winter
Journal:  Cardiology       Date:  2021-02-05       Impact factor: 1.869

Review 7.  Participation and adherence to cardiac rehabilitation programs. A systematic review.

Authors:  Alberto Ruano-Ravina; Carlos Pena-Gil; Emad Abu-Assi; Sergio Raposeiras; Arnoud van 't Hof; Esther Meindersma; Eva Irene Bossano Prescott; Jose Ramón González-Juanatey
Journal:  Int J Cardiol       Date:  2016-08-13       Impact factor: 4.164

8.  Adherence of heart failure patients to exercise: barriers and possible solutions: a position statement of the Study Group on Exercise Training in Heart Failure of the Heart Failure Association of the European Society of Cardiology.

Authors:  Viviane M Conraads; Christi Deaton; Ewa Piotrowicz; Nuria Santaularia; Stephanie Tierney; Massimo F Piepoli; Burkert Pieske; Jean-Paul Schmid; Kenneth Dickstein; Piotr P Ponikowski; Tiny Jaarsma
Journal:  Eur J Heart Fail       Date:  2012-04-11       Impact factor: 15.534

Review 9.  Epidemiology and aetiology of heart failure.

Authors:  Boback Ziaeian; Gregg C Fonarow
Journal:  Nat Rev Cardiol       Date:  2016-03-03       Impact factor: 32.419

10.  The global health and economic burden of hospitalizations for heart failure: lessons learned from hospitalized heart failure registries.

Authors:  Andrew P Ambrosy; Gregg C Fonarow; Javed Butler; Ovidiu Chioncel; Stephen J Greene; Muthiah Vaduganathan; Savina Nodari; Carolyn S P Lam; Naoki Sato; Ami N Shah; Mihai Gheorghiade
Journal:  J Am Coll Cardiol       Date:  2014-02-05       Impact factor: 24.094

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