Literature DB >> 35928086

A Study on the Detection Rates and Location of Sentinel Lymph Node in Patients with Gynecologic Cancers.

Anupama Rajanbabu1, Anandita Anandita1, Viral Patel1, Akhila Appukuttan1.   

Abstract

Introduction: Sentinel lymph node mapping is emerging as an accurate technique to assess the lymph nodal status while reducing surgical and postoperative morbidity. Present study looks into the detection rates and location of sentinel nodes during Sentinel node mapping when Indocyanine green dye was used as a tracer.
Methods: This is a single institutional study with details retrieved from a prospectively maintained database. All patients who underwent sentinel node mapping using ICG dye for atypical hyperplasia, endometrial and cervical cancers from February 2015 to April 2020 were included. Location of the sentinel node was taken from the graphical record maintained during surgery. The data obtained are expressed as number and percentage and/or mean and standard deviation for continuous variables. Chi-square test was performed to compare categorical variables.
Results: Two hundred and seventy-nine patients underwent sentinel node mapping with ICG dye during this period. Mapping was successful in 270 patients (96.8%) with 85% having successful bilateral mapping. Obturator was the most common location (52%) followed by external iliac (34%). There was no significant difference in detection among patients with BMI less than 30 or more than 30. The detection rate across various histologies of endometrial cancer was also similar.
Conclusion: Sentinel node mapping using ICG dye has got excellent overall and bilateral detection rates making it a valuable tool. Obturator was found to be the most common location for the sentinel node. Mapping using ICG dye yield good detection rates in all histologies of endometrial cancer and in patients with high BMI. © Federation of Obstetric & Gynecological Societies of India 2021.

Entities:  

Keywords:  Cervical cancer; Endometrial cancer; Indocyanine green dye; Sentinel lymph node

Year:  2021        PMID: 35928086      PMCID: PMC9343550          DOI: 10.1007/s13224-021-01509-7

Source DB:  PubMed          Journal:  J Obstet Gynaecol India        ISSN: 0975-6434


  13 in total

1.  Comparing indocyanine green, technetium, and blue dye for sentinel lymph node mapping in endometrial cancer.

Authors:  J How; W H Gotlieb; J Z Press; J Abitbol; M Pelmus; A Ferenczy; S Probst; R Gotlieb; S Brin; S Lau
Journal:  Gynecol Oncol       Date:  2015-04-12       Impact factor: 5.482

2.  Can sentinel lymph node biopsy replace pelvic lymphadenectomy for early cervical cancer?

Authors:  Genevieve K Lennox; Allan Covens
Journal:  Gynecol Oncol       Date:  2016-10-11       Impact factor: 5.482

Review 3.  Sentinel lymph node assessment in endometrial cancer: a systematic review and meta-analysis.

Authors:  Anna Jo Bodurtha Smith; Amanda Nickles Fader; Edward J Tanner
Journal:  Am J Obstet Gynecol       Date:  2016-11-18       Impact factor: 8.661

4.  The utility of sentinel lymph node mapping in the management of endometrial atypical hyperplasia.

Authors:  Omar Touhami; Jean Grégoire; Marie-Claude Renaud; Alexandra Sebastianelli; Katherine Grondin; Marie Plante
Journal:  Gynecol Oncol       Date:  2017-12-28       Impact factor: 5.482

Review 5.  Revised FIGO staging for carcinoma of the cervix uteri.

Authors:  Neerja Bhatla; Jonathan S Berek; Mauricio Cuello Fredes; Lynette A Denny; Seija Grenman; Kanishka Karunaratne; Sean T Kehoe; Ikuo Konishi; Alexander B Olawaiye; Jaime Prat; Rengaswamy Sankaranarayanan; James Brierley; David Mutch; Denis Querleu; David Cibula; Michael Quinn; Hennie Botha; Lax Sigurd; Laurel Rice; Hee-Sug Ryu; Hextan Ngan; Johanna Mäenpää; Andri Andrijono; Gatot Purwoto; Amita Maheshwari; Uttam D Bafna; Marie Plante; Jayashree Natarajan
Journal:  Int J Gynaecol Obstet       Date:  2019-01-17       Impact factor: 3.561

Review 6.  Sentinel node mapping with indocyanine green and endoscopic near-infrared fluorescence imaging in endometrial cancer. A pilot study and review of the literature.

Authors:  Marie Plante; Omar Touhami; Xuan-Bich Trinh; Marie-Claude Renaud; Alexandra Sebastianelli; Katherine Grondin; Jean Gregoire
Journal:  Gynecol Oncol       Date:  2015-03-11       Impact factor: 5.482

7.  Detection of sentinel lymph nodes in minimally invasive surgery using indocyanine green and near-infrared fluorescence imaging for uterine and cervical malignancies.

Authors:  Elizabeth L Jewell; Juan Juan Huang; Nadeem R Abu-Rustum; Ginger J Gardner; Carol L Brown; Yukio Sonoda; Richard R Barakat; Douglas A Levine; Mario M Leitao
Journal:  Gynecol Oncol       Date:  2014-02-28       Impact factor: 5.482

Review 8.  Indocyanine green and infrared fluorescence in detection of sentinel lymph nodes in endometrial and cervical cancer staging - a systematic review.

Authors:  Anabela Rocha; Ana Maria Domínguez; Fabrice Lécuru; Nicolas Bourdel
Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2016-09-30       Impact factor: 2.435

9.  Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial.

Authors:  Michael Frumovitz; Marie Plante; Paula S Lee; Samith Sandadi; James F Lilja; Pedro F Escobar; Lilian T Gien; Diana L Urbauer; Nadeem R Abu-Rustum
Journal:  Lancet Oncol       Date:  2018-08-22       Impact factor: 41.316

10.  Controversies in the treatment of early stage endometrial carcinoma.

Authors:  Joshua Z Press; Walter H Gotlieb
Journal:  Obstet Gynecol Int       Date:  2012-03-26
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