Literature DB >> 3592664

Monoclonal antibody CC3C195, which detects cancer-associated antigens in serum, binds to the human Lea blood group antigen and to its sialylated derivative.

S Fukuta, J L Magnani, P K Gaur, V Ginsburg.   

Abstract

Mouse monoclonal antibody CC3C195, which detects elevated levels of its antigen in sera from many patients with colon and pancreatic cancer, binds with high affinity to the sialylated human Lea blood group antigen NeuAc alpha 2-3Gal beta 1-3 [Fuc alpha 1-4]GlcNac . . . and with lower affinity to the Lea blood group antigen itself.

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Year:  1987        PMID： 3592664     DOI： 10.1016/0003-9861(87)90314-6

Source DB:  PubMed          Journal:  Arch Biochem Biophys        ISSN： 0003-9861            Impact factor:   4.013


  4 in total

1.  Evaluation of CEA, CA 19-9, CA-50, CA-195, and TATI with special reference to pancreatic disorders.

Authors:  P Masson; B Pålsson; A Andren-Sandberg
Journal:  Int J Pancreatol       Date:  1991-05

2.  Comparative analysis of cancer-associated antigen CA-195, CA 19-9 and carcinoembryonic antigen in diagnosis, follow-up and monitoring of response to chemotherapy in patients with gastrointestinal cancer.

Authors:  G Kornek; D Depisch; E M Temsch; W Scheithauer
Journal:  J Cancer Res Clin Oncol       Date:  1991       Impact factor: 4.553

3.  Comparison of four serum tumour markers in the diagnosis of colorectal carcinoma.

Authors:  Y T van der Schouw; A L Verbeek; T Wobbes; M F Segers; C M Thomas
Journal:  Br J Cancer       Date:  1992-07       Impact factor: 7.640

4.  Serum tumor markers in pancreatic cancer-recent discoveries.

Authors:  Felix Rückert; Christian Pilarsky; Robert Grützmann
Journal:  Cancers (Basel)       Date:  2010-06-02       Impact factor: 6.639
  4 in total

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