Literature DB >> 3592565

An improved extraction procedure for an HPLC method for cyclosporin A in whole blood and plasma.

S Maguire, F Kyne, D UaConaill.   

Abstract

Cyclosporin A (CyA) was assayed by high performance liquid chromatography (HPLC) following extraction of the whole blood or plasma with diethyl ether and chromatography on a Sep-Pak Silica cartridge. Using carefully chosen volumes and ratios of ethyl acetate and hexane in the eluting sequences on the Sep-Pak, the major interferent present in normal blood and serum was eliminated.

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Year:  1987        PMID: 3592565     DOI: 10.1177/000456328702400206

Source DB:  PubMed          Journal:  Ann Clin Biochem        ISSN: 0004-5632            Impact factor:   2.057


  1 in total

1.  The management of heart transplant recipients treated with cyclosporine in Ireland: monitoring of cyclosporine concentrations in blood.

Authors:  F Kyne; S Maguire; D UaConaill; S O'Broin; E Clarke; S McCann; P Dervan; A E Wood
Journal:  Ir J Med Sci       Date:  1990 Sep-Dec       Impact factor: 1.568

  1 in total

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