Literature DB >> 35922557

Hybrid brains: the ethics of transplanting human neurons into animals.

Kendall Powell.   

Abstract

Entities:  

Keywords:  Developmental biology; Ethics; Neuroscience; Stem cells

Mesh：

Year:  2022        PMID： 35922557     DOI： 10.1038/d41586-022-02073-4

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   69.504


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  10 in total

1.  An in vivo model of functional and vascularized human brain organoids.

Authors:  Abed AlFatah Mansour; J Tiago Gonçalves; Cooper W Bloyd; Hao Li; Sarah Fernandes; Daphne Quang; Stephen Johnston; Sarah L Parylak; Xin Jin; Fred H Gage
Journal:  Nat Biotechnol       Date:  2018-04-16       Impact factor: 54.908

2.  Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo.

Authors:  Ira Espuny-Camacho; Kimmo A Michelsen; David Gall; Daniele Linaro; Anja Hasche; Jérôme Bonnefont; Camilia Bali; David Orduz; Angéline Bilheu; Adèle Herpoel; Nelle Lambert; Nicolas Gaspard; Sophie Péron; Serge N Schiffmann; Michele Giugliano; Afsaneh Gaillard; Pierre Vanderhaeghen
Journal:  Neuron       Date:  2013-02-06       Impact factor: 17.173

3.  Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo.

Authors:  Tao Tan; Jun Wu; Chenyang Si; Shaoxing Dai; Youyue Zhang; Nianqin Sun; E Zhang; Honglian Shao; Wei Si; Pengpeng Yang; Hong Wang; Zhenzhen Chen; Ran Zhu; Yu Kang; Reyna Hernandez-Benitez; Llanos Martinez Martinez; Estrella Nuñez Delicado; W Travis Berggren; May Schwarz; Zongyong Ai; Tianqing Li; Concepcion Rodriguez Esteban; Weizhi Ji; Yuyu Niu; Juan Carlos Izpisua Belmonte
Journal:  Cell       Date:  2021-04-15       Impact factor: 41.582

4.  Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain.

Authors:  Ira Espuny-Camacho; Amaia M Arranz; Mark Fiers; An Snellinx; Kunie Ando; Sebastian Munck; Jerome Bonnefont; Laurie Lambot; Nikky Corthout; Lorna Omodho; Elke Vanden Eynden; Enrico Radaelli; Ina Tesseur; Selina Wray; Andreas Ebneth; John Hardy; Karelle Leroy; Jean-Pierre Brion; Pierre Vanderhaeghen; Bart De Strooper
Journal:  Neuron       Date:  2017-02-23       Impact factor: 17.173

5.  Neural blastocyst complementation enables mouse forebrain organogenesis.

Authors:  Amelia N Chang; Zhuoyi Liang; Hai-Qiang Dai; Aimee M Chapdelaine-Williams; Nick Andrews; Roderick T Bronson; Bjoern Schwer; Frederick W Alt
Journal:  Nature       Date:  2018-10-10       Impact factor: 49.962

6.  Transfer of a functional human immune system to mice with severe combined immunodeficiency.

Authors:  D E Mosier; R J Gulizia; S M Baird; D B Wilson
Journal:  Nature       Date:  1988-09-15       Impact factor: 49.962

7.  Interspecies organogenesis generates autologous functional islets.

Authors:  Tomoyuki Yamaguchi; Hideyuki Sato; Megumi Kato-Itoh; Teppei Goto; Hiromasa Hara; Makoto Sanbo; Naoaki Mizuno; Toshihiro Kobayashi; Ayaka Yanagida; Ayumi Umino; Yasunori Ota; Sanae Hamanaka; Hideki Masaki; Sheikh Tamir Rashid; Masumi Hirabayashi; Hiromitsu Nakauchi
Journal:  Nature       Date:  2017-01-25       Impact factor: 49.962

8.  Cerebral organoids model human brain development and microcephaly.

Authors:  Madeline A Lancaster; Magdalena Renner; Carol-Anne Martin; Daniel Wenzel; Louise S Bicknell; Matthew E Hurles; Tessa Homfray; Josef M Penninger; Andrew P Jackson; Juergen A Knoblich
Journal:  Nature       Date:  2013-08-28       Impact factor: 49.962

9.  Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits.

Authors:  Daniele Linaro; Ben Vermaercke; Ryohei Iwata; Arjun Ramaswamy; Baptiste Libé-Philippot; Leila Boubakar; Brittany A Davis; Keimpe Wierda; Kristofer Davie; Suresh Poovathingal; Pier-Andrée Penttila; Angéline Bilheu; Lore De Bruyne; David Gall; Karl-Klaus Conzelmann; Vincent Bonin; Pierre Vanderhaeghen
Journal:  Neuron       Date:  2019-11-21       Impact factor: 17.173

10.  In vivo modeling of human neuron dynamics and Down syndrome.

Authors:  Raquel Real; Manuel Peter; Antonio Trabalza; Shabana Khan; Mark A Smith; Joana Dopp; Samuel J Barnes; Ayiba Momoh; Alessio Strano; Emanuela Volpi; Graham Knott; Frederick J Livesey; Vincenzo De Paola
Journal:  Science       Date:  2018-10-11       Impact factor: 47.728
  10 in total
  1 in total

Review 1.  Cerebral Organoids as an Experimental Platform for Human Neurogenomics.

Authors:  Tomasz J Nowakowski; Sofie R Salama
Journal:  Cells       Date:  2022-09-08       Impact factor: 7.666
  1 in total

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