Literature DB >> 359193

Quantitative metabolic profiling based on gas chromatography.

S C Gates, C C Sweeley.   

Abstract

The quantitative metabolic profiles of volatilizable components of human biological fluids, particularly urinary organic acids, is reviewed, with emphasis on the use of gas-chromatography/mass spectrometer/computer systems. Various definitions of metabolic profiling are considered and techniques for obtaining such profiles are discussed. The role of computer processing of such data is examined, and statistical techniques for treating quantitative metabolic profiles are suggested.

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Year:  1978        PMID： 359193

Source DB:  PubMed          Journal:  Clin Chem        ISSN： 0009-9147            Impact factor:   8.327


  11 in total

1.  Statins increase hepatic cholesterol synthesis and stimulate fecal cholesterol elimination in mice.

Authors:  Marleen Schonewille; Jan Freark de Boer; Laura Mele; Henk Wolters; Vincent W Bloks; Justina C Wolters; Jan A Kuivenhoven; Uwe J F Tietge; Gemma Brufau; Albert K Groen
Journal:  J Lipid Res       Date:  2016-06-16       Impact factor: 5.922

Review 2.  Overview of mass spectrometry-based metabolomics: opportunities and challenges.

Authors:  G A Nagana Gowda; Danijel Djukovic
Journal:  Methods Mol Biol       Date:  2014

Review 3.  UPLC-MS for metabolomics: a giant step forward in support of pharmaceutical research.

Authors:  Ala F Nassar; Terence Wu; Samuel F Nassar; Adam V Wisnewski
Journal:  Drug Discov Today       Date:  2016-12-02       Impact factor: 7.851

4.  Comprehensive Two-Dimensional Gas Chromatography Mass Spectrometry-Based Metabolomics.

Authors:  Md Aminul Islam Prodhan; Craig McClain; Xiang Zhang
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

Review 5.  Reflections on my career in analytical chemistry and biochemistry.

Authors:  Charles C Sweeley
Journal:  Proc Jpn Acad Ser B Phys Biol Sci       Date:  2010       Impact factor: 3.493

6.  Bile acid sequestration reduces plasma glucose levels in db/db mice by increasing its metabolic clearance rate.

Authors:  Maxi Meissner; Hilde Herrema; Theo H van Dijk; Albert Gerding; Rick Havinga; Theo Boer; Michael Müller; Dirk-Jan Reijngoud; Albert K Groen; Folkert Kuipers
Journal:  PLoS One       Date:  2011-11-07       Impact factor: 3.240

Review 7.  Noninvasive metabolic profiling for painless diagnosis of human diseases and disorders.

Authors:  Mainak Mal
Journal:  Future Sci OA       Date:  2016-06-10

8.  Metabolomics: a promising diagnostic and therapeutic implement for breast cancer.

Authors:  Zhanghan Chen; Zehuan Li; Haoran Li; Ying Jiang
Journal:  Onco Targets Ther       Date:  2019-08-21       Impact factor: 4.147

9.  Biochemical competition makes fatty-acid β-oxidation vulnerable to substrate overload.

Authors:  Karen van Eunen; Sereh M J Simons; Albert Gerding; Aycha Bleeker; Gijs den Besten; Catharina M L Touw; Sander M Houten; Bert K Groen; Klaas Krab; Dirk-Jan Reijngoud; Barbara M Bakker
Journal:  PLoS Comput Biol       Date:  2013-08-15       Impact factor: 4.475

Review 10.  Pharmacometabolomics in Early-Phase Clinical Development.

Authors:  T Burt; S Nandal
Journal:  Clin Transl Sci       Date:  2016-04-29       Impact factor: 4.689
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