Literature DB >> 35917466

Microdystrophin Therapy Rescues Impaired Na Currents in Cardiac Purkinje Fibers From Dystrophin-Deficient Mdx Mice.

Janine Ebner1, Xiufang Pan2, Yongping Yue2, Spyridon Sideromenos1, Jessica Marksteiner1, Xaver Koenig1, Karlheinz Hilber1, Dongsheng Duan2,3.   

Abstract

Entities:  

Keywords:  arrhythmia, cardiac; dystrophin; mice; muscular dystrophy, Duchenne; myocytes, cardiac

Mesh：

Substances：

Year:  2022        PMID： 35917466      PMCID： PMC9396648          DOI： 10.1161/CIRCEP.122.011161

Source DB:  PubMed          Journal:  Circ Arrhythm Electrophysiol        ISSN： 1941-3084


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  5 in total

1.  Cardiac-Specific Expression of ΔH2-R15 Mini-Dystrophin Normalized All Electrocardiogram Abnormalities and the End-Diastolic Volume in a 23-Month-Old Mouse Model of Duchenne Dilated Cardiomyopathy.

Authors:  Nalinda B Wasala; Jin-Hong Shin; Yi Lai; Yongping Yue; Federica Montanaro; Dongsheng Duan
Journal:  Hum Gene Ther       Date:  2018-03-22       Impact factor: 5.695

Review 2.  Duchenne muscular dystrophy.

Authors:  Dongsheng Duan; Nathalie Goemans; Shin'ichi Takeda; Eugenio Mercuri; Annemieke Aartsma-Rus
Journal:  Nat Rev Dis Primers       Date:  2021-02-18       Impact factor: 52.329

3.  Reduced Na+ current in Purkinje fibers explains cardiac conduction defects and arrhythmias in Duchenne muscular dystrophy.

Authors:  Janine Ebner; Pavel Uhrin; Petra L Szabo; Attila Kiss; Bruno K Podesser; Hannes Todt; Karlheinz Hilber; Xaver Koenig
Journal:  Am J Physiol Heart Circ Physiol       Date:  2020-05-08       Impact factor: 5.125

Review 4.  Systemic AAV Micro-dystrophin Gene Therapy for Duchenne Muscular Dystrophy.

Authors:  Dongsheng Duan
Journal:  Mol Ther       Date:  2018-07-17       Impact factor: 11.454

5.  Hierarchical statistical techniques are necessary to draw reliable conclusions from analysis of isolated cardiomyocyte studies.

Authors:  Markus B Sikkel; Darrel P Francis; James Howard; Fabiana Gordon; Christina Rowlands; Nicholas S Peters; Alexander R Lyon; Sian E Harding; Kenneth T MacLeod
Journal:  Cardiovasc Res       Date:  2017-12-01       Impact factor: 10.787
  5 in total

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