Literature DB >> 35916957

How to take advantage of easily available biomarkers in patients with IgA nephropathy: IgA and C3 in serum and kidney biopsies.

Małgorzata Mizerska-Wasiak1.   

Abstract

IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide. It is diagnosed based on clinical and histological features including predominant IgA deposits in kidney biopsy. The multi-hit theory, based on the production of GDIgA1 and anti-GDIgA1 antibodies, and complement activation via alternative and lectin pathways and also a genetic tendency are crucial in the pathogenesis of IgAN. The aim of the present review is to summarize the utility of routine diagnostic tests in IgA nephropathy, such as IgA and C3 in serum and kidney biopsy specimens, for predicting the disease progression. The paper also contains data on new markers used in the diagnosis and prognosis of IgA nephropathy.
© 2022. The Author(s), under exclusive licence to International Pediatric Nephrology Association.

Entities:  

Keywords:  C3; C3 deposits; IgA; IgA deposits; IgA nephropathy

Year:  2022        PMID： 35916957     DOI： 10.1007/s00467-022-05644-9

Source DB:  PubMed          Journal:  Pediatr Nephrol        ISSN： 0931-041X            Impact factor:   3.651


  37 in total

1.  Aberrantly glycosylated IgA1 in IgA nephropathy patients is recognized by IgG antibodies with restricted heterogeneity.

Authors:  Hitoshi Suzuki; Run Fan; Zhixin Zhang; Rhubell Brown; Stacy Hall; Bruce A Julian; W Winn Chatham; Yusuke Suzuki; Robert J Wyatt; Zina Moldoveanu; Jeannette Y Lee; James Robinson; Milan Tomana; Yasuhiko Tomino; Jiri Mestecky; Jan Novak
Journal:  J Clin Invest       Date:  2009-05-26       Impact factor: 14.808

2.  The Clinical Significance of Uric Acid and Complement Activation in the Progression of IgA Nephropathy.

Authors:  Yasar Caliskan; Yasemin Ozluk; Dilara Celik; Nida Oztop; Aysun Aksoy; Ayse Serra Ucar; Halil Yazici; Isin Kilicaslan; Mehmet Sukru Sever
Journal:  Kidney Blood Press Res       Date:  2016-02-26       Impact factor: 2.687

Review 3.  The pathophysiology of IgA nephropathy.

Authors:  Hitoshi Suzuki; Krzysztof Kiryluk; Jan Novak; Zina Moldoveanu; Andrew B Herr; Matthew B Renfrow; Robert J Wyatt; Francesco Scolari; Jiri Mestecky; Ali G Gharavi; Bruce A Julian
Journal:  J Am Soc Nephrol       Date:  2011-09-23       Impact factor: 10.121

4.  Updating the International IgA Nephropathy Prediction Tool for use in children.

Authors:  Sean J Barbour; Rosanna Coppo; Lee Er; Maria Luisa Russo; Zhi-Hong Liu; Jie Ding; Ritsuko Katafuchi; Norishige Yoshikawa; Hong Xu; Shoji Kagami; Yukio Yuzawa; Francesco Emma; Alexandra Cambier; Licia Peruzzi; Robert J Wyatt; Daniel C Cattran
Journal:  Kidney Int       Date:  2020-11-18       Impact factor: 10.612

5.  Clinical and histological differences between adults and children in new onset IgA nephropathy.

Authors:  Alexandra Cambier; Marion Rabant; Khalil El Karoui; Michel Peuchmaur; Aude Servais; Alexandre Hertig; Georges Deschenes; Remi Salomon; Julien Hogan; Thomas Robert
Journal:  Pediatr Nephrol       Date:  2020-05-22       Impact factor: 3.714

Review 6.  IgA nephropathy in children and in adults: two separate entities or the same disease?

Authors:  Rosanna Coppo; Thomas Robert
Journal:  J Nephrol       Date:  2020-04-20       Impact factor: 3.902

Review 7.  Is IgA nephropathy the same disease in different parts of the world?

Authors:  Hong Zhang; Jonathan Barratt
Journal:  Semin Immunopathol       Date:  2021-08-20       Impact factor: 9.623

8.  IgA Nephropathy in Children: A Multicenter Study in Poland.

Authors:  M Mizerska-Wasiak; A Turczyn; A Such; K Cichoń-Kawa; J Małdyk; M Miklaszewska; J Pietrzyk; A Rybi-Szumińska; A Wasilewska; A Firszt-Adamczyk; R Stankiewicz; M Szczepańska; B Bieniaś; M Zajączkowska; A Pukajło-Marczyk; D Zwolińska; K Siniewicz-Luzeńczyk; M Tkaczyk; K Gadomska-Prokop; R Grenda; U Demkow; M Pańczyk-Tomaszewska
Journal:  Adv Exp Med Biol       Date:  2016       Impact factor: 2.622

Review 9.  Natural history of primary IgA nephropathy.

Authors:  François C Berthoux; Hesham Mohey; Aïda Afiani
Journal:  Semin Nephrol       Date:  2008-01       Impact factor: 5.299

Review 10.  The Emerging Role of Complement Proteins as a Target for Therapy of IgA Nephropathy.

Authors:  Dana V Rizk; Nicolas Maillard; Bruce A Julian; Barbora Knoppova; Todd J Green; Jan Novak; Robert J Wyatt
Journal:  Front Immunol       Date:  2019-03-19       Impact factor: 7.561
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