Literature DB >> 35916396

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Year:  2022        PMID: 35916396      PMCID: PMC9344821          DOI: 10.1111/jcmm.17487

Source DB:  PubMed          Journal:  J Cell Mol Med        ISSN: 1582-1838            Impact factor:   5.295


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In Yilan Song et al., the image for Vimentin of TGF‐beta1‐NC group in Figure 5F contains error during image preparation. The correct figure is shown below. The authors confirm all results and conclusions of this article remain unchanged. The authors confirm that there are no conflicts of interest.
FIGURE 5

DEK positively regulates the progression of EMT in human bronchial epithelial cell. (A) Flow cytometry analysis of TGF‐β1 expression in the BEAS‐2B cells with ovDEK or shDEK (right panel) and DEK expression after treating with TGF‐β1 (left panel). (B) Relative level of TGF‐β1 and DEK. (C) The DEK, α‐SMA, vimentin, E‐cadherin and Snail + Slug were detected after TGF‐β1 treatment using Western blotting. (D) Relative density of above proteins. (E) mRNA levels of α‐SMA, vimentin and E‐cadherin were detected. (F) Immunofluorescence was performed for analysis of E‐cadherin and vimentin in the BEAS‐2B cells. NC, negative control cells; ovDEK, cells transfected with DEK; shNC, cells transfected with scrambled shRNA; shDEK, cells transfected with DEK shRNA.*p < 0.05, vs control group. # p < 0.05, ovDEK vs TGF‐β1 + NC group; shDEK v sTGF‐β1 + shNC group.

DEK positively regulates the progression of EMT in human bronchial epithelial cell. (A) Flow cytometry analysis of TGF‐β1 expression in the BEAS‐2B cells with ovDEK or shDEK (right panel) and DEK expression after treating with TGF‐β1 (left panel). (B) Relative level of TGF‐β1 and DEK. (C) The DEK, α‐SMA, vimentin, E‐cadherin and Snail + Slug were detected after TGF‐β1 treatment using Western blotting. (D) Relative density of above proteins. (E) mRNA levels of α‐SMA, vimentin and E‐cadherin were detected. (F) Immunofluorescence was performed for analysis of E‐cadherin and vimentin in the BEAS‐2B cells. NC, negative control cells; ovDEK, cells transfected with DEK; shNC, cells transfected with scrambled shRNA; shDEK, cells transfected with DEK shRNA.*p < 0.05, vs control group. # p < 0.05, ovDEK vs TGF‐β1 + NC group; shDEK v sTGF‐β1 + shNC group.
  1 in total

1.  DEK-targeting aptamer DTA-64 attenuates bronchial EMT-mediated airway remodelling by suppressing TGF-β1/Smad, MAPK and PI3K signalling pathway in asthma.

Authors:  Yilan Song; Zhiguang Wang; Jingzhi Jiang; Yihua Piao; Li Li; Chang Xu; Hongmei Piao; Liangchang Li; Guanghai Yan
Journal:  J Cell Mol Med       Date:  2020-10-30       Impact factor: 5.295

  1 in total

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