Literature DB >> 35911571

Probing a Stochastic Epidemic Hepatitis C Virus Model with a Chronically Infected Treated Population.

S P Rajasekar1,2, M Pitchaimani1, Quanxin Zhu3.   

Abstract

The hepatitis C virus is hitherto a tremendous threat to human beings, but many researchers have analyzed mathematical models for hepatitis C virus transmission dynamics only in the deterministic case. Stochasticity plays an immense role in pathology and epidemiology. Hence, the main theme of this article is to investigate a stochastic epidemic hepatitis C virus model with five states of epidemiological classification: susceptible, acutely infected, chronically infected, recovered or removed and chronically infected, and treated. The stochastic hepatitis C virus model in epidemiology is established based on the environmental influence on individuals, is manifested by stochastic perturbations, and is proportional to each state. We assert that the stochastic HCV model has a unique global positive solution and attains sufficient conditions for the extinction of the hepatotropic RNA virus. Furthermore, by constructing a suitable Lyapunov function, we obtain sufficient conditions for the existence of an ergodic stationary distribution of the solutions to the stochastic HCV model. Moreover, this article confirms that using numerical simulations, the six parameters of the stochastic HCV model can have a high impact over the disease transmission dynamics, specifically the disease transmission rate, the rate of chronically infected population, the rate of progression to chronic infection, the treatment failure rate of chronically infected population, the recovery rate from chronic infection and the treatment rate of the chronically infected population. Eventually, numerical simulations validate the effectiveness of our theoretical conclusions. © Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences 2022.

Entities:  

Keywords:  acute and chronically infected; chronically infected treated; extinction; hepatitis C virus; stationary distribution

Year:  2022        PMID: 35911571      PMCID: PMC9310688          DOI: 10.1007/s10473-022-0521-1

Source DB:  PubMed          Journal:  Acta Math Sci        ISSN: 0252-9602            Impact factor:   1.085


  20 in total

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Review 4.  Reversion of disease manifestations after HCV eradication.

Authors:  Adriaan J van der Meer; Marina Berenguer
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5.  Model for hepatitis C virus transmissions.

Authors:  Elamin H Elbasha
Journal:  Math Biosci Eng       Date:  2013-08       Impact factor: 2.080

Review 6.  Natural history of hepatitis C.

Authors:  Rachel H Westbrook; Geoffrey Dusheiko
Journal:  J Hepatol       Date:  2014-11-03       Impact factor: 25.083

Review 7.  Hepatitis C virus: Virology, diagnosis and treatment.

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Journal:  World J Hepatol       Date:  2015-06-08

Review 8.  Clinical significance of hepatitis C virus genotypes.

Authors:  N N Zein
Journal:  Clin Microbiol Rev       Date:  2000-04       Impact factor: 26.132

Review 9.  Is sexual contact a major mode of hepatitis C virus transmission?

Authors:  Rania A Tohme; Scott D Holmberg
Journal:  Hepatology       Date:  2010-10       Impact factor: 17.425

10.  The influence of quadratic Lévy noise on the dynamic of an SIC contagious illness model: New framework, critical comparison and an application to COVID-19 (SARS-CoV-2) case.

Authors:  Yassine Sabbar; Driss Kiouach; S P Rajasekar; Salim El Azami El-Idrissi
Journal:  Chaos Solitons Fractals       Date:  2022-04-25       Impact factor: 9.922

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