Dear Editor,we would like to share ideas on “Effects of anti‐SARS‐CoV‐2 vaccination on safety and disease exacerbation in patients with Behçet syndrome in a monocentric cohort”.
According to Apaydin et al, COVID‐19 vaccines are well tolerated by Behçet's syndrome patients, whereas more side effects appear following messenger RNA vaccines. Regardless of the vaccine type, exacerbations following the COVID‐19 vaccine are frequent, primarily involving the mucosa and joints, while exacerbations involving other organs are uncommon.
We both agree there may be a connection between the COVID‐19 infection and the vaccine. Even while the COVID‐19 vaccination is beneficial, we are all concerned that it might also be dangerous. It is impossible to tell what led to the hematologic issue in this case because there was insufficient pre‐vaccination information on the health and immunological status of vaccine recipients. Due to conflicting facts, people may grow discouraged and oppose immunizations. Patient comorbidity may be the cause of the issue.
It was evident that the patient had a clinical illness, but this did not mean there were no other co‐morbid diseases. A group of people with known pre‐vaccination immunological and health statuses who were afterward followed to assess how the vaccine affected the disease would provide more conclusive evidence on this topic.