Literature DB >> 35908146

Surgical outcome of scoliosis in patients with Marfan syndrome.

Chatupon Chotigavanichaya1, Panjapol Vatidvarodom1, Thanase Ariyawatkul1, Monchai Ruangchainikom1, Sirichai Wilartratsami1, Areesak Chotivichit1, Surin Thanapipatsiri1, Borriwat Santipas1, Nath Adulkasem1, Panya Luksanapruksa2.   

Abstract

PURPOSE: To evaluate clinical and radiographic outcomes after surgical scoliosis correction and posterior instrumented fusion in SMF patients.
METHODS: A single-center medical database was reviewed to identify MF patients who presented with scoliosis from 2000 to 2015. Patients who underwent spinal fusion surgery were included. Demographic, operative and clinical data were reviewed, and the preoperative, postoperative, and latest follow-up radiographic parameters were compared.
RESULTS: Twelve patients were identified (2 males, 10 females) with an average age at surgery of 14.4 ± 2.6 years. Comorbidities were found in 84.6%. Most patients (90.9%) presented with a right thoracic curve. The average preoperative Cobb angle was 75.6 ± 15.5 degrees. Posterior instrumented spinal fusion was performed in all patients (1 hook/pedicular screw and 11 pedicle screws only). The average follow-up period was 6.8 ± 3.1 years. The mean postoperative Cobb angle after surgery and at the final follow-up was 33.4 ± 18.0 degrees and 35.5 ± 18.4 degrees, respectively. There was a statistically significant difference among the preoperative and postoperative Cobb angles (p < 0.001), but no significant difference among the sagittal angles. Two perioperative complications including superficial wound infection and broken rods were observed.
CONCLUSIONS: Posterior scoliosis correction and instrumented spinal fusion resulted in a satisfactory outcome in MF patients. Perioperative complications are not uncommon; however, no neurological complication or spinal decompensation was observed in this study. LEVEL OF EVIDENCE: IV.
© 2022. The Author(s), under exclusive licence to Scoliosis Research Society.

Entities:  

Keywords:  Marfan syndrome; Posterior spinal fusion; Scoliosis; Surgical outcome

Mesh:

Year:  2022        PMID: 35908146     DOI: 10.1007/s43390-022-00547-z

Source DB:  PubMed          Journal:  Spine Deform        ISSN: 2212-134X


  32 in total

1.  Marfan syndrome caused by a recurrent de novo missense mutation in the fibrillin gene.

Authors:  H C Dietz; G R Cutting; R E Pyeritz; C L Maslen; L Y Sakai; G M Corson; E G Puffenberger; A Hamosh; E J Nanthakumar; S M Curristin
Journal:  Nature       Date:  1991-07-25       Impact factor: 49.962

2.  Revised diagnostic criteria for the Marfan syndrome.

Authors:  A De Paepe; R B Devereux; H C Dietz; R C Hennekam; R E Pyeritz
Journal:  Am J Med Genet       Date:  1996-04-24

Review 3.  The Marfan syndrome: diagnosis and management.

Authors:  R E Pyeritz; V A McKusick
Journal:  N Engl J Med       Date:  1979-04-05       Impact factor: 91.245

Review 4.  Unusual orthopedic manifestations of neurofibromatosis.

Authors:  K N Joseph; J R Bowen; G D MacEwen
Journal:  Clin Orthop Relat Res       Date:  1992-05       Impact factor: 4.176

5.  Toward an understanding of dural ectasia: a light microscopy study in a murine model of Marfan syndrome.

Authors:  Kevin B Jones; Loretha Myers; Daniel P Judge; Patricia A Kirby; Harry C Dietz; Paul D Sponseller
Journal:  Spine (Phila Pa 1976)       Date:  2005-02-01       Impact factor: 3.468

6.  Spinal deformity in Marfan syndrome.

Authors:  J G Birch; J A Herring
Journal:  J Pediatr Orthop       Date:  1987 Sep-Oct       Impact factor: 2.324

7.  Genetic linkage of the Marfan syndrome, ectopia lentis, and congenital contractural arachnodactyly to the fibrillin genes on chromosomes 15 and 5. The International Marfan Syndrome Collaborative Study.

Authors:  P Tsipouras; R Del Mastro; M Sarfarazi; B Lee; E Vitale; A H Child; M Godfrey; R B Devereux; D Hewett; B Steinmann
Journal:  N Engl J Med       Date:  1992-04-02       Impact factor: 91.245

8.  Spinal deformities in Marfan's syndrome.

Authors:  R Savini; S Cervellati; E Beroaldo
Journal:  Ital J Orthop Traumatol       Date:  1980-04

9.  The thoracolumbar spine in Marfan syndrome.

Authors:  P D Sponseller; W Hobbs; L H Riley; R E Pyeritz
Journal:  J Bone Joint Surg Am       Date:  1995-06       Impact factor: 5.284

10.  Scoliotic curve patterns in patients with Marfan syndrome.

Authors:  Yann Glard; Franck Launay; Grégory Edgard-Rosa; Patrick Collignon; Jean-Luc Jouve; Gérard Bollini
Journal:  J Child Orthop       Date:  2008-03-15       Impact factor: 1.548

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.