Masatomo Maeda1, Masahiro Nonaka2, Nobuaki Naito1, Katsuya Ueno1, Takamasa Kamei1, Akio Asai1. 1. Department of Neurosurgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata City, Osaka, 573-1010, Japan. 2. Department of Neurosurgery, Kansai Medical University, 2-5-1 Shinmachi, Hirakata City, Osaka, 573-1010, Japan. nonakamasa65@gmail.com.
Abstract
OBJECTIVE: A case of low-grade glioma in which 5-aminolevulinic acid (5-ALA) fluorescence was visualized by a digital exoscope is presented. CASE PRESENTATION: A 14-year-old girl with recurrent paroxysmal episodes of a strange smell and nausea underwent magnetic resonance imaging (MRI) for further investigation. The MRI showed a tumor with an enhanced nodule in the right temporal lobe. The patient received 5-ALA preoperatively, and intraoperative observation using a 4 K-3-dimension digital exoscope (Olympus ORBEYE) showed that the tumor was fluorescent, which was useful in determining the extent of tumor removal. Postoperative MRI showed that the tumor was completely removed. The histopathological diagnosis was pleomorphic xanthoastrocytoma. She was discharged without any complications. CONCLUSIONS: 5-ALA-fluorescence-guided resection of low-grade glioma using the ORBEYE was useful for determining the extent of removal.
OBJECTIVE: A case of low-grade glioma in which 5-aminolevulinic acid (5-ALA) fluorescence was visualized by a digital exoscope is presented. CASE PRESENTATION: A 14-year-old girl with recurrent paroxysmal episodes of a strange smell and nausea underwent magnetic resonance imaging (MRI) for further investigation. The MRI showed a tumor with an enhanced nodule in the right temporal lobe. The patient received 5-ALA preoperatively, and intraoperative observation using a 4 K-3-dimension digital exoscope (Olympus ORBEYE) showed that the tumor was fluorescent, which was useful in determining the extent of tumor removal. Postoperative MRI showed that the tumor was completely removed. The histopathological diagnosis was pleomorphic xanthoastrocytoma. She was discharged without any complications. CONCLUSIONS: 5-ALA-fluorescence-guided resection of low-grade glioma using the ORBEYE was useful for determining the extent of removal.
Authors: Michael A Vogelbaum; Derek Kroll; Arnold Etame; Nam Tran; James Liu; Antonika Ford; Emily Sparr; Youngchul Kim; Peter Forsyth; Solmaz Sahebjam; Sepideh Mokhtari; Edwin Peguero; Robert Macaulay Journal: World Neurosurg Date: 2021-02-06 Impact factor: 2.104
Authors: Sergey A Goryaynov; Vladimir A Okhlopkov; Denis A Golbin; Konstantin A Chernyshov; Dmitrij V Svistov; Boris V Martynov; Alexandr V Kim; Vadim A Byvaltsev; Galina V Pavlova; Artem Batalov; Nikolay A Konovalov; Petr V Zelenkov; Victor B Loschenov; Alexandr A Potapov Journal: Front Oncol Date: 2019-09-06 Impact factor: 6.244