Literature DB >> 35901833

Clinical research in ovarian cancer: consensus recommendations from the Gynecologic Cancer InterGroup.

Ignace Vergote1, Antonio Gonzalez-Martin2, Domenica Lorusso3, Charlie Gourley4, Mansoor Raza Mirza5, Jean-Emmanuel Kurtz6, Aikou Okamoto7, Kathleen Moore8, Frédéric Kridelka9, Iain McNeish10, Alexander Reuss11, Bénédicte Votan12, Andreas du Bois13, Sven Mahner14, Isabelle Ray-Coquard15, Elise C Kohn16, Jonathan S Berek17, David S P Tan18, Nicoletta Colombo19, Rongyu Zang20, Nicole Concin21, Dearbhaile O'Donnell22, Alejandro Rauh-Hain23, C Simon Herrington4, Christian Marth24, Andres Poveda25, Keiichi Fujiwara26, Gavin C E Stuart27, Amit M Oza28, Michael A Bookman29.   

Abstract

The Gynecologic Cancer InterGroup (GCIG) sixth Ovarian Cancer Conference on Clinical Research was held virtually in October, 2021, following published consensus guidelines. The goal of the consensus meeting was to achieve harmonisation on the design elements of upcoming trials in ovarian cancer, to select important questions for future study, and to identify unmet needs. All 33 GCIG member groups participated in the development, refinement, and adoption of 20 statements within four topic groups on clinical research in ovarian cancer including first line treatment, recurrent disease, disease subgroups, and future trials. Unanimous consensus was obtained for 14 of 20 statements, with greater than 90% concordance in the remaining six statements. The high acceptance rate following active deliberation among the GCIG groups confirmed that a consensus process could be applied in a virtual setting. Together with detailed categorisation of unmet needs, these consensus statements will promote the harmonisation of international clinical research in ovarian cancer.
Copyright © 2022 Elsevier Ltd. All rights reserved.

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Year:  2022        PMID: 35901833      PMCID: PMC9465953          DOI: 10.1016/S1470-2045(22)00139-5

Source DB:  PubMed          Journal:  Lancet Oncol        ISSN: 1470-2045            Impact factor:   54.433


  47 in total

Review 1.  Key statistical concepts in cancer research.

Authors:  Qian Shi; Daniel J Sargent
Journal:  Clin Adv Hematol Oncol       Date:  2015-03

2.  Bevacizumab combined with chemotherapy for platinum-resistant recurrent ovarian cancer: The AURELIA open-label randomized phase III trial.

Authors:  Eric Pujade-Lauraine; Felix Hilpert; Béatrice Weber; Alexander Reuss; Andres Poveda; Gunnar Kristensen; Roberto Sorio; Ignace Vergote; Petronella Witteveen; Aristotelis Bamias; Deolinda Pereira; Pauline Wimberger; Ana Oaknin; Mansoor Raza Mirza; Philippe Follana; David Bollag; Isabelle Ray-Coquard
Journal:  J Clin Oncol       Date:  2014-03-17       Impact factor: 44.544

3.  Randomized Phase III Trial of Irinotecan Plus Cisplatin Compared With Paclitaxel Plus Carboplatin As First-Line Chemotherapy for Ovarian Clear Cell Carcinoma: JGOG3017/GCIG Trial.

Authors:  Toru Sugiyama; Aikou Okamoto; Takayuki Enomoto; Tetsutaro Hamano; Eriko Aotani; Yasuhisa Terao; Nao Suzuki; Mikio Mikami; Nobuo Yaegashi; Kiyoko Kato; Hiroyuki Yoshikawa; Yoshihito Yokoyama; Hiroshi Tanabe; Koji Nishino; Hiroyuki Nomura; Jae-Weon Kim; Byoung-Gie Kim; Sandro Pignata; Jerome Alexandre; John Green; Seiji Isonishi; Fumitoshi Terauchi; Keiichi Fujiwara; Daisuke Aoki
Journal:  J Clin Oncol       Date:  2016-07-11       Impact factor: 44.544

4.  Morphologic Reproducibility, Genotyping, and Immunohistochemical Profiling Do Not Support a Category of Seromucinous Carcinoma of the Ovary.

Authors:  Peter F Rambau; John B McIntyre; Jennifer Taylor; Sandra Lee; Travis Ogilvie; Anna Sienko; Don Morris; Máire A Duggan; W Glenn McCluggage; Martin Köbel
Journal:  Am J Surg Pathol       Date:  2017-05       Impact factor: 6.394

5.  Carboplatin-based doublet plus bevacizumab beyond progression versus carboplatin-based doublet alone in patients with platinum-sensitive ovarian cancer: a randomised, phase 3 trial.

Authors:  Sandro Pignata; Domenica Lorusso; Florence Joly; Ciro Gallo; Nicoletta Colombo; Cristiana Sessa; Aristotelis Bamias; Vanda Salutari; Frédèric Selle; Simona Frezzini; Ugo De Giorgi; Patricia Pautier; Alessandra Bologna; Michele Orditura; Coraline Dubot; Angiolo Gadducci; Serafina Mammoliti; Isabelle Ray-Coquard; Elena Zafarana; Enrico Breda; Laure Favier; Antonio Ardizzoia; Saverio Cinieri; Rémy Largillier; Daniela Sambataro; Emmanuel Guardiola; Rossella Lauria; Carmela Pisano; Francesco Raspagliesi; Giovanni Scambia; Gennaro Daniele; Francesco Perrone
Journal:  Lancet Oncol       Date:  2021-02       Impact factor: 41.316

6.  Ovarian cancer in elderly patients: carboplatin and pegylated liposomal doxorubicin versus carboplatin and paclitaxel in late relapse: a Gynecologic Cancer Intergroup (GCIG) CALYPSO sub-study.

Authors:  J E Kurtz; M C Kaminsky; A Floquet; A S Veillard; R Kimmig; A Dorum; L Elit; M Buck; E Petru; N Reed; G Scambia; N Varsellona; C Brown; E Pujade-Lauraine
Journal:  Ann Oncol       Date:  2011-03-14       Impact factor: 32.976

7.  Ovarian carcinoma histotype determination is highly reproducible, and is improved through the use of immunohistochemistry.

Authors:  Martin Köbel; Julia Bak; Björn I Bertelsen; Olli Carpen; Anni Grove; Estrid S Hansen; Anne-Marie Levin Jakobsen; Marianne Lidang; Anna Måsbäck; Anna Tolf; C Blake Gilks; Joseph W Carlson
Journal:  Histopathology       Date:  2014-03-07       Impact factor: 5.087

Review 8.  Optimal primary therapy of ovarian cancer.

Authors:  M A Bookman
Journal:  Ann Oncol       Date:  2016-04       Impact factor: 32.976

9.  Long-term results of dose-dense paclitaxel and carboplatin versus conventional paclitaxel and carboplatin for treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer (JGOG 3016): a randomised, controlled, open-label trial.

Authors:  Noriyuki Katsumata; Makoto Yasuda; Seiji Isonishi; Fumiaki Takahashi; Hirofumi Michimae; Eizo Kimura; Daisuke Aoki; Toshiko Jobo; Shoji Kodama; Fumitoshi Terauchi; Toru Sugiyama; Kazunori Ochiai
Journal:  Lancet Oncol       Date:  2013-08-13       Impact factor: 41.316

10.  Randomized Trial of Cytoreductive Surgery for Relapsed Ovarian Cancer.

Authors:  Philipp Harter; Jalid Sehouli; Ignace Vergote; Gwenael Ferron; Alexander Reuss; Werner Meier; Stefano Greggi; Berit J Mosgaard; Frederic Selle; Frédéric Guyon; Christophe Pomel; Fabrice Lécuru; Rongyu Zang; Elisabeth Avall-Lundqvist; Jae-Weon Kim; Jordi Ponce; Francesco Raspagliesi; Gunnar Kristensen; Jean-Marc Classe; Peter Hillemanns; Pernille Jensen; Annette Hasenburg; Sadaf Ghaem-Maghami; Mansoor R Mirza; Bente Lund; Alexander Reinthaller; Ana Santaballa; Adeola Olaitan; Felix Hilpert; Andreas du Bois
Journal:  N Engl J Med       Date:  2021-12-02       Impact factor: 91.245

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