Literature DB >> 35898368

Wandering Cancer Cells: Metastatic Renal Cell Carcinoma Without Evidence of a Primary Tumor.

Swe Swe Hlaing1, Devashish Desai1, Aakash Goyal1, Navjot Rai1, Ronald Swaab2.   

Abstract

Renal cell carcinoma (RCC) usually presents clinically in the advanced stage including bone metastasis. However metastatic RCC without evidence of a primary tumor in the kidney is extremely rare. We herein report a case of a 70-year-old male initially evaluated for bone lesion and diagnosed with biopsy-proven metastatic clear cell RCC without a renal primary. Given the rare nature of the disease, there is no standardized course of treatment that has yet been established. We believe that our case will add to the body of knowledge about uncommon oncologic instances and consolidate the information that has already been published.
Copyright © 2022, Hlaing et al.

Entities:  

Keywords:  clear renal cell carcinoma; oncology imaging; renal neoplasm; renal pathology; unknown primary site

Year:  2022        PMID: 35898368      PMCID: PMC9309091          DOI: 10.7759/cureus.26305

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  11 in total

1.  The evolving landscape of metastatic renal cell carcinoma.

Authors:  Daniel Y C Heng; Toni K Choueiri
Journal:  Am Soc Clin Oncol Educ Book       Date:  2012

2.  The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based study.

Authors:  Jenny J Ko; Wanling Xie; Nils Kroeger; Jae-Lyun Lee; Brian I Rini; Jennifer J Knox; Georg A Bjarnason; Sandy Srinivas; Sumanta K Pal; Takeshi Yuasa; Martin Smoragiewicz; Frede Donskov; Ravindran Kanesvaran; Lori Wood; D Scott Ernst; Neeraj Agarwal; Ulka N Vaishampayan; Sun-Young Rha; Toni K Choueiri; Daniel Y C Heng
Journal:  Lancet Oncol       Date:  2015-02-12       Impact factor: 41.316

Review 3.  An evaluation of nivolumab for the treatment of metastatic renal cell carcinoma.

Authors:  Kevin Zarrabi; Shenhong Wu
Journal:  Expert Opin Biol Ther       Date:  2018-06-04       Impact factor: 4.388

4.  Orbit and sinonasal metastasis as presenting sign of renal cell carcinoma.

Authors:  Zalathiel Barajas-Ochoa; Giselle Alexandra Suero-Abreu; Aldo Barajas-Ochoa
Journal:  BMJ Case Rep       Date:  2021-04-13

5.  Distribution of metastatic sites in renal cell carcinoma: a population-based analysis.

Authors:  M Bianchi; M Sun; C Jeldres; S F Shariat; Q-D Trinh; A Briganti; Z Tian; J Schmitges; M Graefen; P Perrotte; M Menon; F Montorsi; P I Karakiewicz
Journal:  Ann Oncol       Date:  2011-09-02       Impact factor: 32.976

6.  Renal cell cancer without a renal primary.

Authors:  M Wayne; W Wang; J Bratcher; B Cumani; F Kasmin; A Cooperman
Journal:  World J Surg Oncol       Date:  2010-03-22       Impact factor: 2.754

7.  Renal cell carcinoma presenting as mandibular metastasis.

Authors:  Hassan Ahmadnia; Negar Mokhtari Amirmajdi; Ehsan Mansourian
Journal:  Saudi J Kidney Dis Transpl       Date:  2013-07

8.  Contemporary epidemiology of renal cell cancer.

Authors:  Wong-Ho Chow; Susan S Devesa
Journal:  Cancer J       Date:  2008 Sep-Oct       Impact factor: 3.360

9.  Metastatic renal cell carcinoma without evidence of a primary renal tumour.

Authors:  R M Kumar; T Aziz; H Jamshaid; J Gill; A Kapoor
Journal:  Curr Oncol       Date:  2014-06       Impact factor: 3.677

10.  Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma.

Authors:  Kevin Bi; Meng Xiao He; Ziad Bakouny; Abhay Kanodia; Sara Napolitano; Jingyi Wu; Grace Grimaldi; David A Braun; Michael S Cuoco; Angie Mayorga; Laura DelloStritto; Gabrielle Bouchard; John Steinharter; Alok K Tewari; Natalie I Vokes; Erin Shannon; Maxine Sun; Jihye Park; Steven L Chang; Bradley A McGregor; Rizwan Haq; Thomas Denize; Sabina Signoretti; Jennifer L Guerriero; Sébastien Vigneau; Orit Rozenblatt-Rosen; Asaf Rotem; Aviv Regev; Toni K Choueiri; Eliezer M Van Allen
Journal:  Cancer Cell       Date:  2021-03-11       Impact factor: 31.743

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