| Literature DB >> 35897077 |
Feng Liu1, Jianfeng Xie2, Xiwen Zhang1, Zongsheng Wu1, Shi Zhang1, Ming Xue1, Jianxiao Chen1, Yi Yang1, Haibo Qiu1.
Abstract
Entities:
Year: 2022 PMID: 35897077 PMCID: PMC9327333 DOI: 10.1186/s13287-022-03078-6
Source DB: PubMed Journal: Stem Cell Res Ther ISSN: 1757-6512 Impact factor: 8.079
Fig. 3Effect of MSC-TGF-β1 on inflammatory cytokines in the plasma and macrophages in tissue. a, b, c: The levels of IL-6, IL-1β, and IL-10 in the plasma were tested by ELISA (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). d, e, f: The levels of macrophages in lung, liver and spleen tissue were assayed by immumohistochemical staining. (n = 3, *p < 0.05 vs. the sham group; #p < 0.05 vs. the CLP group; &p < 0.05 vs. the MSC-NC group). Scale bar = 100 μm. Abbreviations: CLP: cecal ligation and puncture; MSCs, mesenchymal stem cells; MSC-NC: mesenchymal stem cell carrying GFP; MSC-TGF-β1: TGF-β1 overexpressing MSC