Literature DB >> 35896849

Documentation of recovery from vitamin A deficiency-related retinopathy via multimodal imaging and electroretinogram testing.

Stephanie Choi1, Saagar Pandit1, Sachi A Patil2, Scott E Brodie3.   

Abstract

PURPOSE: To describe vitamin A deficiency using multimodal functional visual assessments and imaging. METHODS/CASE: A 50-year-old female with past medical history significant for Roux-en-Y gastric bypass surgery complained of nyctalopia and "yellowing" of vision.
RESULTS: Vitamin A levels were noted to be < 0.06 mg/L (normal 0.3-0.12 mg/L). Fundus examination was notable for peripheral yellow punctate lesions, superior arcuate defects on HVF 30-2 testing, an indistinct ellipsoid zone on SD-OCT, and absent rod responses and severely reduced amplitudes for the cone photoreceptors on full-field ERG. These findings resolved with initiation of parenteral vitamin A supplementation.
CONCLUSION: This report documents an example of vitamin A deficiency in the developed world. We aim to provide a comprehensive description of clinical examination and multimodal imaging findings before and after vitamin supplementation for vitamin A deficiency.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Bariatric surgery; Electroretinography; Full-field ERG; Optical coherence tomography; Visual field; Vitamin A deficiency

Mesh:

Substances:

Year:  2022        PMID: 35896849     DOI: 10.1007/s10633-022-09888-6

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   1.854


  17 in total

Review 1.  Rapid recovery of night blindness due to obesity surgery after vitamin A repletion therapy.

Authors:  Y Spits; J-J De Laey; B P Leroy
Journal:  Br J Ophthalmol       Date:  2004-04       Impact factor: 4.638

2.  Case Report: Delayed Vitamin A Retinopathy Secondary to Bariatric Surgery.

Authors:  Raman Bhakhri; William H Ridder; Sean Adrean
Journal:  Optom Vis Sci       Date:  2019-03       Impact factor: 1.973

3.  Analysis of vitamin levels and deficiencies in bariatric surgery patients: a single-institutional analysis.

Authors:  Lisa M Johnson; Sayeed Ikramuddin; Daniel B Leslie; Bridget Slusarek; Anthony A Killeen
Journal:  Surg Obes Relat Dis       Date:  2019-05-02       Impact factor: 4.734

Review 4.  Multiple functions of vitamin A.

Authors:  G Wolf
Journal:  Physiol Rev       Date:  1984-07       Impact factor: 37.312

5.  Vitamin A deficiency and xerophthalmic fundus in autoimmune hepatitis and cirrhosis.

Authors:  Clement C Chow; William F Mieler
Journal:  Retin Cases Brief Rep       Date:  2014

Review 6.  The effect of vitamin A on epithelial integrity.

Authors:  F S McCullough; C A Northrop-Clewes; D I Thurnham
Journal:  Proc Nutr Soc       Date:  1999-05       Impact factor: 6.297

7.  Xerophthalmia and acquired night blindness in a patient with a history of gastrointestinal neoplasia and normal serum vitamin A levels.

Authors:  Anastasios Anastasakis; Sotiris Plainis; Trisevgeni Giannakopoulou; Elisavet Papadimitraki; Charalambos Fanouriakis; Miltiadis K Tsilimbaris
Journal:  Doc Ophthalmol       Date:  2013-01-20       Impact factor: 2.379

Review 8.  Vitamin A metabolism in the retinal pigment epithelium: genes, mutations, and diseases.

Authors:  Debra A Thompson; Andreas Gal
Journal:  Prog Retin Eye Res       Date:  2003-09       Impact factor: 21.198

9.  Irreversible effects on visible light on the retina: role of vitamin A.

Authors:  W K Noell; R Albrecht
Journal:  Science       Date:  1971-04-02       Impact factor: 47.728

10.  Vitamin A transport between retina and pigment epithelium--an interstitial protein carrying endogenous retinol (interstitial retinol-binding protein).

Authors:  G I Liou; C D Bridges; S L Fong; R A Alvarez; F Gonzalez-Fernandez
Journal:  Vision Res       Date:  1982       Impact factor: 1.886

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