| Literature DB >> 35896506 |
Vincent J Major1, Simon A Jones1, Narges Razavian1, Ashley Bagheri1, Felicia Mendoza1, Jay Stadelman1, Leora I Horwitz1,2, Jonathan Austrian2, Yindalon Aphinyanaphongs1.
Abstract
BACKGROUND: We previously developed and validated a predictive model to help clinicians identify hospitalized adults with coronavirus disease 2019 (COVID-19) who may be ready for discharge given their low risk of adverse events. Whether this algorithm can prompt more timely discharge for stable patients in practice is unknown.Entities:
Mesh:
Year: 2022 PMID: 35896506 PMCID: PMC9329139 DOI: 10.1055/s-0042-1750416
Source DB: PubMed Journal: Appl Clin Inform ISSN: 1869-0327 Impact factor: 2.762
Fig. 1CONSORT diagram. CONSORT, Consolidated Standards of Reporting Trials extension for interventions involving AI.
Baseline characteristics of enrolled patients
| No. (%) | ||||||
|---|---|---|---|---|---|---|
| All patients (n = 1,010) | Control group (n = 497) | Intervention group (n = 513) | ||||
| Age, years | ||||||
| Mean (SD) | 58.9 | (20.1) | 58.4 | (20.2) | 59.4 | (20.0) |
| Sex | ||||||
| Male | 484 | (47.9) | 223 | (44.9) | 261 | (50.9) |
| Female | 526 | (52.1) | 274 | (55.1) | 252 | (49.1) |
| Ethnicity | ||||||
| Hispanic | 258 | (25.5) | 128 | (25.8) | 130 | (25.3) |
| Race | ||||||
| White | 511 | (50.6) | 245 | (49.3) | 266 | (51.9) |
| African American (Black) | 122 | (12.1) | 72 | (14.5) | 50 | (9.7) |
| Asian | 61 | (6.0) | 31 | (6.2) | 30 | (5.8) |
| Native American | 12 | (1.2) | 5 | (1.0) | 7 | (1.4) |
| Pacific Islander | 9 | (0.9) | 6 | (1.2) | 3 | (0.6) |
| Other | 295 | (29.2) | 138 | (27.8) | 157 | (30.6) |
| Location | ||||||
| Tisch/Kimmel | 270 | (26.7) | 140 | (28.2) | 130 | (25.3) |
| Orthopedics | 18 | (1.8) | 9 | (1.8) | 9 | (1.8) |
| Brooklyn | 416 | (41.2) | 210 | (42.3) | 206 | (40.2) |
| Long Island | 306 | (30.3) | 138 | (27.8) | 168 | (32.7) |
Differences in primary and secondary outcomes at discharge and 30-day follow-up
| Control group | Intervention group | p-Value | |||
|---|---|---|---|---|---|
| Primary outcome |
(
|
(
| |||
| gLOS, days, median [IQR] | 3.23 | [1.75–6.00] | 3.18 | [1.76–5.95] | 0.8 |
| Secondary outcome |
(
|
(
| |||
| LOS, days, median [IQR] | 4.50 | [2.34–7.65] | 4.20 | [2.33–7.51] | 0.8 |
| Adverse safety outcomes in scored patients discharged alive. |
(
|
(
| |||
| 30-d re-presentation, no (%) | 115 | (18.0%) | 138 | (20.9%) | 0.2 |
| 30-d mortality, no (%) | 3 | (0.47%) | 8 | (1.2%) | 0.2 |
| Adverse safety outcomes in all scored patients. |
(
|
(
| |||
| Inpatient mortality/hospice, no (%) | 63 | (9.0%) | 50 | (7.0%) | 0.2 |
| Any adverse outcome, no (%) | 178 | (25.3%) | 191 | (26.8%) | 0.6 |
Abbreviations: gLOS, length of stay after first green score; LOS, length of stay; IQR, interquartile range.
Fig. 2Adoption and sustained use of two communication channels available to clinicians. Colored dots represent the weekly total number of times the score was displayed to any user via each display channel, either a personal or shared patient list ( A ) or the patient-specific report of COVID-19 information ( B ). The weekly census of hospitalized COVID-19 patients is shown with grey dots for reference (calculated as the number of unique encounters scored by the system in that week).