| Literature DB >> 35895413 |
Alvaro Guerra-Amor1, Ane Lopez-Gonzalez2, Pau Bosch-Nicolau3, Breogan Rodriguez-Acevedo4, Ana Zabalza4, Elena Sulleiro5, Juan Espinosa-Pereiro3, Maria Luisa Aznar3, Fernando Salvador3, Adrián Sánchez-Montalvá3, Israel Molina3.
Abstract
Leishmaniasis is a protozoan disease caused by species of genus Leishmania. Immunosuppression increases the risk of severe clinical forms and impairs response to treatment. The expansion of the use of immunomodulatory drugs for different conditions has raised the number of these cases. In this report, we present a case of visceral leishmaniasis in a patient with multiple sclerosis (MS) under fingolimod treatment. He presented with the triad of fever, visceromegaly, and pancytopenia and was diagnosed by the presence of amastigotes in a bone marrow sample. Furthermore, we discuss the previous published cases of MS patients under different immunosuppressant therapies to highlight its risk in endemic areas and suggest a therapeutic approach.Entities:
Year: 2022 PMID: 35895413 PMCID: PMC9393455 DOI: 10.4269/ajtmh.22-0117
Source DB: PubMed Journal: Am J Trop Med Hyg ISSN: 0002-9637 Impact factor: 3.707