| Literature DB >> 35892031 |
Anahita Malvea1, Farbod Babaei2, Chadwick Boulay3,4, Adam Sachs3,4,5, Jeongwon Park2,6.
Abstract
Parkinson's Disease (PD) is a neurodegenerative disorder that manifests as an impairment of motor and non-motor abilities due to a loss of dopamine input to deep brain structures. While there is presently no cure for PD, a variety of pharmacological and surgical therapeutic interventions have been developed to manage PD symptoms. This review explores the past, present and future outlooks of PD treatment, with particular attention paid to deep brain stimulation (DBS), the surgical procedure to deliver DBS, and its limitations. Finally, our group's efforts with respect to brain mapping for DBS targeting will be discussed. © Korean Society of Medical and Biological Engineering 2022.Entities:
Keywords: Alzheimer’s; Bradykinesia; Deep brain stimulation (DBS); Dystonia; Essential tremor; Parkinson’s disease (PD); Parkinson’s symptoms; Subthalamic nucleus (STN); Thalamus (VM); Tourette syndrome (TS); Treatment resistant depression (TRD); globus pallidus interna (GPi)
Year: 2022 PMID： 35892031 PMCID： PMC9308849 DOI： 10.1007/s13534-022-00226-y
Source DB: PubMed Journal: Biomed Eng Lett ISSN： 2093-9868