| Literature DB >> 35887847 |
Naoko Izumi1, Tomohiro Matsuo2, Yoshihisa Matsukawa3.
Abstract
This cross-sectional survey study evaluated associations between physician-patient communication and patient satisfaction with overactive bladder (OAB) medical care or clinical effectiveness. Japanese patients aged ≥50 years with OAB who had taken OAB medication within 2 years received a web-based survey regarding OAB medical care, physician-patient communication on OAB symptoms and treatment, and OAB symptom score (OABSS) change with treatment. Associations between physician-patient communication and patient satisfaction or OAB medication effectiveness (≥3-point improvement in OABSS) were investigated by multivariate analysis with confounding factors. Stratified analyses were performed based on medication continuation or discontinuation (for reasons except symptom improvement). Of the 1004 respondents included in the analyses, 58.0% continued treatment, and 23.7% discontinued for reasons except symptom improvement. Satisfaction with OAB care was associated with reported effectiveness, medication side effects, physician-patient communication, and whether medication was switched. Medication effectiveness was associated with patient-physician communication, female sex, and not switching medication. Significantly more patients in the continuation group were satisfied and had improvement of ≥3 points in OABSS (p < 0.001 for both). The findings suggest that, in Japan, adequate physician-patient communication contributes significantly to improving clinical effectiveness and satisfaction with medical care in OAB patients as well as treatment continuation.Entities:
Keywords: communication; medication adherence; overactive; physician–patient relations; surveys and questionnaires; urinary bladder
Year: 2022 PMID: 35887847 PMCID: PMC9320694 DOI: 10.3390/jcm11144087
Source DB: PubMed Journal: J Clin Med ISSN: 2077-0383 Impact factor: 4.964
Figure 1Survey questions. OABSS, overactive bladder symptom score.
Patient characteristics.
| Total Population | ||
|---|---|---|
| Sex | ||
| Male | 591 | (58.9) |
| Female | 413 | (41.1) |
| Age, years | ||
| Mean (SD) | 70.3 | (7.1) |
| Median (IQR) | 71.0 | (10.0) |
| <70 years | 385 | (38.3) |
| ≥70 years | 619 | (61.7) |
| OABSS prior to medication | ||
| Mean (SD) | 9.0 | (2.6) |
| Median (IQR) | 9.0 | (4.0) |
| Change in OABSS | ||
| Mean (SD) | 3.1 | (2.9) |
| Median (IQR) | 3.0 | (4.0) |
| Clinically significant improvement in OABSS | ||
| Unimproved (<3 points) | 471 | (46.9) |
| Improved (≥3 points) | 533 | (53.1) |
| Medication adherence | ||
| Continued | 582 | (58.0) |
| Discontinued | 422 | (42.0) |
| Patient-reported reason for discontinuation | ||
| Symptom improvement | 184 | (43.6) |
| No symptom improvement | 116 | (27.5) |
| Worsening symptoms | 2 | (0.5) |
| Side effects | 46 | (10.9) |
| Used on an as needed basis | 63 | (14.9) |
| Other | 42 | (10.0) |
| Discontinued for any reason other than symptom improvement | 238 | (23.7) |
| Discontinued due to symptom improvement | 184 | (18.3) |
| Duration of medication exposure | ||
| <1 month | 70 | (7.0) |
| 1 to <3 months | 141 | (14.0) |
| 3 to <6 months | 141 | (14.0) |
| 6 to <12 months | 169 | (16.8) |
| ≥12 months | 483 | (48.1) |
| Switched medication | ||
| Yes | 387 | (38.5) |
| No | 617 | (61.5) |
| Department consulted | ||
| Urology | 733 | (73.0) |
| Internal medicine | 240 | (23.9) |
| Other | 26 | (2.6) |
| Unknown | 5 | (0.5) |
| Type of medical facility visited | ||
| Hospital | 391 | (38.9) |
| Clinic | 608 | (60.6) |
| Other | 5 | (0.5) |
| Comorbidities | ||
| Any | 730 | (72.7) |
| Hypertension | 413 | (41.1) |
| Dyslipidemia (hyperlipidemia) | 193 | (19.2) |
| Diabetes mellitus | 141 | (14.0) |
| Benign prostatic hyperplasia (male patients) | 277 | (46.9) |
| Other | 114 | (11.4) |
| None of the above | 274 | (27.3) |
Data are presented as n (%) unless otherwise noted. IQR, interquartile range; OABSS, overactive bladder symptom score; SD, standard deviation.
Figure 2Results of survey questions (a) (Q1): Effectiveness, side effects of medication, and communication with physician for overactive bladder medical care; (b) (Q2): frequency of talking with your physician about symptoms and treatments related to urination; and (c) (Q3): satisfaction with current overall medical care for overactive bladder.
Endpoint 1: Association with satisfaction with overall medical care for overactive bladder.
| Explanatory Variables | OR | 95% CI | |
|---|---|---|---|
| Q1-1. Medication’s effectiveness | <0.001 | 7.99 | (5.59–11.43) |
| Q1-2. Medication’s side effects | <0.001 | 0.36 | (0.24–0.53) |
| Q1-3. Symptom enquiry | 0.56 | 1.16 | (0.70–1.92) |
| Q1-4. Explanation of treatment method | 0.26 | 1.34 | (0.81–2.24) |
| Q1-5. Explanation of effects | 0.37 | 1.25 | (0.76–2.07) |
| Q1-6. Explanation of side effects | 0.02 | 1.61 | (1.07–2.44) |
| Q1-7. Explanation of treatment options and consultation | 0.06 | 1.47 | (0.98–2.19) |
| Q1-8. Satisfaction with treatment method | <0.001 | 2.20 | (1.43–3.38) |
| Q1-9. Atmosphere conducive to asking questions | <0.001 | 2.50 | (1.56–4.01) |
| Q2. Talking with physician about symptoms and treatments related to urination at least once every 10 visits | 0.23 | 1.44 | (0.79–2.63) |
| Age (≥70 years old) | 0.75 | 0.94 | (0.63–1.40) |
| Sex (female) | 0.44 | 1.17 | (0.78–1.76) |
| Duration of medication exposure is ≥3 months | 0.20 | 0.75 | (0.49–1.16) |
| Have not switched to another type of overactive bladder medication since starting to take it | 0.045 | 1.44 | (1.01–2.05) |
Chi-square probability: <0.001; Hosmer–Lemeshow p-value: 0.28; correct discrimination rate: 0.80. CI, confidence interval; OR, odds ratio.
Endpoint 2: Association with the effectiveness of overactive bladder medication (presence or absence of improvement ≥3 points in OABSS).
| Explanatory Variables | OR | 95% CI | |
|---|---|---|---|
| Q1-3. Symptom enquiry | <0.001 | 2.45 | (1.62–3.70) |
| Q1-4. Explanation of treatment method | 0.18 | 1.34 | (0.87–2.06) |
| Q1-5. Explanation of effects | 0.70 | 0.92 | (0.60–1.41) |
| Q1-6. Explanation of side effects | 0.80 | 0.96 | (0.68–1.34) |
| Q1-7. Explanation of treatment options and consultation | 0.42 | 0.87 | (0.63–1.21) |
| Q1-8. Satisfaction with treatment method | <0.001 | 1.97 | (1.36–2.85) |
| Q1-9. Atmosphere conducive to asking questions | 0.74 | 0.94 | (0.63–1.40) |
| Q2. Talking with physician about symptoms and treatments related to urination at least once every 10 visits. | 0.47 | 0.84 | (0.52–1.35) |
| Age (≥70 years old) | 0.86 | 1.03 | (0.75–1.40) |
| Sex (female) | <0.001 | 1.89 | (1.38–2.58) |
| Duration of medication exposure is ≥3 months. | 0.06 | 1.38 | (0.99–1.92) |
| Have not switched to another type of overactive bladder medication since starting to take it. | 0.002 | 1.53 | (1.16–2.01) |
Chi-square probability: <0.001; Hosmer–Lemeshow p-value: 0.34; correct discrimination rate: 0.63. CI, confidence interval; OABSS, overactive bladder symptom score; OR, odds ratio.
Stratified analysis in the discontinuation and continuation groups.
| Association with Medical Care Satisfaction (Endpoint 1) | Association with Effectiveness of OAB Medication * (Endpoint 2) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Discontinuation Group | Continuation Group | Discontinuation Group | Continuation Group | |||||||||
| Explanatory Variables | Adjusted OR | 95% CI | Adjusted OR | 95% CI | Adjusted OR | 95% CI | Adjusted OR | 95% CI | ||||
| Q1-1. Medication’s effectiveness | <0.001 | 4.22 | (2.00–8.92) | <0.001 | 8.43 | (5.16–13.78) | - | - | - | - | - | - |
| Q1-2. Medication’s side effects | 0.04 | 0.44 | (0.20–0.97) | <0.001 | 0.34 | (0.19–0.59) | - | - | - | - | - | - |
| Q1-3. Symptom enquiry | 0.11 | 0.41 | (0.14–1.21) | 0.64 | 1.18 | (0.59–2.36) | 0.97 | 1.02 | (0.42–2.43) | 0.001 | 2.59 | (1.46–4.61) |
| Q1-4. Explanation of treatment method | 0.08 | 2.98 | (0.88–10.07) | 0.85 | 0.93 | (0.47–1.85) | 0.20 | 1.91 | (0.71–5.15) | 0.17 | 1.50 | (0.84–2.67) |
| Q1-5. Explanation of effects | 0.67 | 0.78 | (0.25–2.43) | 0.11 | 1.71 | (0.88–3.32) | 0.27 | 0.58 | (0.22–1.53) | 0.92 | 0.97 | (0.55–1.72) |
| Q1-6. Explanation of side effects | 0.006 | 3.47 | (1.43–8.40) | 0.08 | 1.65 | (0.94–2.89) | 0.78 | 1.12 | (0.50–2.49) | 0.86 | 1.04 | (0.67–1.63) |
| Q1-7. Explanation of treatment options and consultation | 0.09 | 2.12 | (0.89–5.05) | 0.38 | 1.27 | (0.74–2.20) | 0.32 | 1.47 | (0.69–3.12) | 0.21 | 0.75 | (0.48–1.18) |
| Q1-8. Satisfaction with treatment method | 0.86 | 1.08 | (0.45–2.62) | <0.001 | 2.81 | (1.55–5.09) | 0.31 | 1.47 | (0.70–3.09) | 0.004 | 2.16 | (1.28–3.64) |
| Q1-9. Atmosphere conducive to asking questions | 0.08 | 2.57 | (0.90–7.35) | 0.01 | 2.32 | (1.19–4.54) | 0.77 | 1.14 | (0.49–2.65) | 0.14 | 0.65 | (0.36–1.16) |
| Q2. Talking with physician about symptoms and treatments related to urination at least once every 10 visits | 0.32 | 2.15 | (0.48–9.65) | 0.20 | 1.76 | (0.74–4.18) | 0.61 | 0.78 | (0.30–2.03) | 0.61 | 0.83 | (0.41–1.69) |
| Age (≥70 years old) | 0.26 | 0.61 | (0.26–1.44) | 0.31 | 1.33 | (0.77–2.32) | 0.76 | 1.12 | (0.53–2.37) | 0.68 | 1.09 | (0.72–1.65) |
| Sex (female) | 0.88 | 0.94 | (0.40–2.22) | 0.23 | 1.42 | (0.81–2.50) | 0.22 | 1.58 | (0.76–3.27) | 0.002 | 1.94 | (1.27–2.95) |
| Duration of medication exposure is ≥3 months | 0.11 | 2.07 | (0.86–5.00) | 0.07 | 0.53 | (0.26–1.06) | 0.32 | 1.45 | (0.69–3.03) | 0.002 | 2.30 | (1.36–3.87) |
| Have not switched to another type of overactive bladder medication since starting to take it | 0.48 | 1.31 | (0.62–2.76) | 0.04 | 1.65 | (1.03–2.65) | 0.63 | 0.86 | (0.46–1.60) | 0.006 | 1.65 | (1.16–2.36) |
* An improvement of ≥3 points in OABSS. CI, confidence interval; OAB, overactive bladder; OABSS, overactive bladder symptom score; OR, odds ratio.
Figure 3Comparison between patients who continued and those who discontinued overactive bladder medication. OABSS, overactive bladder symptom score.