Literature DB >> 35884766

Correction: Hom et al. Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models. BrainSci. 2021, 11, 1220.

Christy L Hom1, Katharine A Kirby2, Joni Ricks-Oddie2,3, David B Keator1, Sharon J Krinsky-McHale4, Margaret B Pulsifer5, Herminia Diana Rosas6, Florence Lai6, Nicole Schupf7,8, Ira T Lott9, Wayne Silverman9.   

Abstract

We would like to submit the following correction to our recently published paper [...].

Entities:  

Year:  2022        PMID: 35884766      PMCID: PMC9313374          DOI: 10.3390/brainsci12070925

Source DB:  PubMed          Journal:  Brain Sci        ISSN: 2076-3425


We would like to submit the following correction to our recently published paper [1].

Error in Tables

In the original publication, there were mistakes in Table 2 and Table 5 as published. The standard deviation listed for the CS group on the DSMSE language test was mistakenly listed as 0.07 in Table 2. The p-value listed for the RADD-2 Expressive Language in Table 5 was mistakenly listed as <.001 in Table 5. The Estimate value for the Purdue Pegboard was mistakenly listed as 0615 in Table 5. The corrected Table 2 and Table 5 appear below.
Table 2

Means and standard deviations of raw test scores by AD status and their hypothesized cognitive domain.

Variable (Range of Scores)DomainCS (n = 103)MCI-DS (n = 41)Mann–Whitney U (p-Value)
Block Design (0–54)Visuomotor23.79 (10.49)17.37 (12.78)3.11 (0.002)
Boston Naming (0–27)Language15.88 (5.51)13.23 (6.91)2.04 (0.041)
Category Fluency (0–17)EF8.23 (3.18)6.82 (3.68)2.21 (0.027)
Cats and Dogs Switch (--17.00–61.80) EF9.80 (11.22)5.05 (11.21)1.82 (0.069)
Cued Recall (3–35) Memory28.61 (6.83)21.38 (9.22)4.43 (0.0001)
DSMSE Language (3–52)Language37.10 (9.07)30.80 (9.63)3.28 (0.001)
DSMSE Memory (0–23)Memory14.08 (4.68)9.80 (4.57)4.62 (0.0001)
DSMSE Visual Spatial (2–8)Visuomotor6.18 (1.09)5.59 (1.01)2.98 (0.003)
mMMSE-DS Anomia (4–20)Language18.18 (2.20)16.49 (4.19)1.55 (0.122)
mMMSE-DS Concentration (0–6)EF3.69 (2.10)2.39 (2.14)3.15 (0.002)
mMMSE-DS Fine Motor (1–10)Visuomotor8.04 (1.29)7.05 (2.28)2.58 (0.010)
mMMSE-DS Orientation (5–30)EF25.46 (5.33)20.87 (6.41)4.75 (0.0001)
Purdue Pegboard Both Hands (0–8)Visuomotor2.62 (1.82)1.51 (1.71)3.14 (0.002)
RADD-2 Digit Span Forward (0–8)EF4.02 (1.66)2.97 (1.80)2.84 (0.005)
RADD-2 Expressive Lang. (0–16)Language11.24 (3.92)8.80 (4.01)3.34 (0.001)
RADD-2 Receptive Lang. (0–12)Language7.56 (2.51)6.80 (2.99)1.08 (0.279)
RADD-2 Sensorimotor (0–7)Visuomotor6.70 (0.50)5.85 (1.50)3.87 (0.0001)
RADD-2 Similarities (0–4)Language2.51 (1.49)1.56 (1.47)3.40 (0.001)
Rivermead Recognition (0–10)Memory5.42 (3.77)2.21 (3.40)3.90 (0.0001)
Selective Reminding Test (1–24)Memory15.50 (5.62)9.18 (4.32)5.70 (0.0001)
Tinetti Gait (4–12)Visuomotor10.75 (1.62)10.37 (1.88)1.47 (0.143)
VMI (1–25)Visuomotor15.45 (3.22)13.98 (3.40)1.75 (0.081)

† Cats and Dogs is measured in seconds; all other scores are measured in points (number correct). EF = executive function.

Table 5

The relationship between sex, premorbid ID, MCI-DS, and cognitive functioning.

Cognitive DomainPredictor VariableEstimateSECRStandardized Regression Weightp-Value
Structural
Language/EFSex−0.0100.075−0.13−0.010.893
Language/EFPID−0.4130.067−6.15−0.41<0.001
Language/EFMCI-DS−0.2380.074−3.23−0.240.001
MemorySex0.0080.0760.110.010.916
MemoryPID−0.2410.075−3.21−0.240.001
MemoryMCI-DS−0.4710.67−7.07−0.47<0.001
VisuomotorSex−0.0930.081−1.14−0.090.255
VisuomotorPID−0.3020.077−3.91−0.30<0.001
VisuomotorMCI-DS−0.3030.78−3.90−0.30<0.001
Measurement
Language/EFBoston Naming0.8790.02338.180.88<0.001
Language/EFDSMSE Language0.8780.02337.810.88<0.001
Language/EFmMMSE Anomia0.7420.04118.140.74<0.001
Language/EFmMMSE Concentration0.7240.04316.530.72<0.001
Language/EFRADD-2 Digit Span Forward0.7820.03621.930.78<0.001
Language/EFRADD-2 Expressive Language0.8740.02337.520.87<0.001
Language/EFRADD-2 Receptive Language0.6830.04716.530.68<0.001
Language/EFRADD-2 Similarities0.7600.03820.050.76<0.001
MemoryCued Recall0.6730.05312.650.67<0.001
MemoryDSMSE Memory0.8580.03227.090.86<0.001
MemoryRivermead Recognition0.7020.05113.870.70<0.001
MemorySelective Reminding Test0.8450.03325.650.85<0.001
VisuomotorBlock Design0.8490.03326.090.85<0.001
VisuomotorDSMSE Visual Spatial0.7970.03817.050.80<0.001
VisuomotorPurdue Pegboard0.6150.5910.390.62<0.001
VisuomotorRADD Sensorimotor0.6240.05810.700.62<0.001
VisuomotorVMI0.7080.04814.770.71<0.001

CR = critical ratio, EF = executive function, MCI = mild cognitive impairment, PID = premorbid level of ID, SE = standard error.

The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.
  1 in total

1.  Cognitive Function during the Prodromal Stage of Alzheimer's Disease in Down Syndrome: Comparing Models.

Authors:  Christy L Hom; Katharine A Kirby; Joni Ricks-Oddie; David B Keator; Sharon J Krinsky-McHale; Margaret B Pulsifer; Herminia Diana Rosas; Florence Lai; Nicole Schupf; Ira T Lott; Wayne Silverman
Journal:  Brain Sci       Date:  2021-09-16
  1 in total

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