| Literature DB >> 35882777 |
Larissa E van Eijk1, Annette K Offringa2, Maria-Elena Bernal3, Arno R Bourgonje4, Harry van Goor1, Jan-Luuk Hillebrands1.
Abstract
Taurine is an amino sulfonic acid that is implicated in numerous physiological functions, including the regulation of oxidative stress, which plays an important role in coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), together with other pathophysiological processes. The recent finding of decreased serum taurine levels in SARS-CoV-2-infected patients, in tandem with its potential modulatory role in COVID-19 due to its antiviral, antioxidant, anti-inflammatory, and vascular-related effects, provides a rationale for considering taurine as a beneficial supplement in patients suffering from COVID-19. Here, we reviewed the potential disease-modifying effects of taurine and combined these with the current knowledge on COVID-19 to clarify the potential role of taurine in this respiratory disease.Entities:
Keywords: Coronavirus disease 2019 (COVID-19); Inflammation; Oxidative stress; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Taurine; Treatment
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Year: 2022 PMID： 35882777 DOI： 10.1007/978-3-030-93337-1_1
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 3.650