Buckling suppression of a thin-walled Miura-origami patterned tube.

In order to improve energy absorption capacity of tubes under axial compression, this work introduces an octagon tube patterned by curved Miura origami pattern and aims at suppressing global buckling of the tube via an appropriate fold line scheme. By categorizing the fold lines of the tube into two types (hinge-like lines and continuous lines) and allocating them to different positions, four arrangement schemes of the lines are developed. Through numerical comparison in force-displacement curve, stress distribution and lateral deformation capacity among four 3-level patterned tubes under different schemes, Scheme 4 (inclined valley lines as hinge-like lines and the others as continuous lines) is found to outperform the others in suppressing global buckling by reducing the magnitude of lateral deformation by up to 59.9% and by delaying the occurrence of global buckling by up to 35.9% compared with the other schemes. To step further, the scheme is applied in a long tube and geometrically different tubes are compared. The results prove that the scheme is potentially an effective way to alleviate buckling instability of a long tube when appropriately designed.

Introduction

Origami is an ancient art of forming planar materials to spatial structures by folding the materials along predetermined fold lines. The intricate structures gain unconventional properties and yield origami-inspired engineering applications including soft robotics [1, 2], self-folding structures [3, 4], biomechanical materials [5, 6] and so on. Among the applications, energy absorbers aim at precluding global buckling and achieving yielding along the entire length by introducing origami patterns as geometrical imperfections.

The concept of origami-inspired energy dissipaters is built on the truth that thin-walled tubes are widely accepted as energy dissipaters for their excellent mechanical performance, manufacturing ease and affordability. Straight square tubes and circular tubes are the most common types of energy dissipaters. Large amount of efforts has been made to investigate the mechanical behaviors of the two types of tubes under axial crushing. Through experimental and numerical study, the deformation modes and energy dissipation characteristics have been investigated and analytical theories have been accordingly proposed [7-9]. Also, tubes with other cross sections have been explored, such as more polygonal tubes [10] and cone tubes [11] and star-shaped tubes [12]. These tubes show highly sensitivity to initial geometrical imperfections and the unpredictable deformation deteriorates the performance under loading. However, at the same time, the study reveals that appropriate imperfections trigger specific deformation modes and consequently alter the response under loading. That inspires the introduction of origami pat-terns into thin-walled tubes. Wu and Hagiwara [13] applied Kresling pattern on aluminum tubes to absorb impact shock and an optimization method of the energy absorption capacity was put forward. Song and Chen [14] proposed a type of tubes with equilateral trapezoid patterns, which were numerically and experimentally verified to improve the crashworthiness by successfully inducing the crushing modes of the tubes. Since then, various types of origami patterns have been designed and applied to tubes, including Miura origami pattern [15, 16], Yoshimura pattern [17], crash box [18, 19], kite-shape pattern [20, 21], waterbomb pattern [22, 23] and so on. These elaborately designed patterns significantly enhance the energy absorption capacity of the tubes. The above-mentioned work meaningfully contributes to the understanding of the applications of origami-based tubes. However, the work is limited to short tubes, for which global buckling is not a problem. When it comes to longer tubes, global buckling is more likely to occur and in turn adversely affects the behavior in terms of significant compression capacity loss, strain concentration at mid-span, sudden force redistribution and material fracture [24]. Therefore, it is necessary to extend the current work to longer tubes.

In this work, an octagon tube patterned by curved Miura origami is introduced and an arrangement scheme of the fold lines is proposed to suppress global buckling of the tube. Through numerical analysis, the superior scheme is proved to be potentially an effective way to alleviate buckling instability of a long tube when appropriately designed.

The main structure of the manuscript is as follows: In the 2nd section, a curved Miura origami-patterned unit is introduced. In the 3rd section, four arrangement schemes of fold lines are developed and the superior one is picked by comparisons of their effects on buckling suppression of the tubes. In the following section, application of the superior scheme to a long tube is given. Finally, conclusions drawn in this work are summarized.

Materials and methods

Curved Miura origami-patterned unit

Curved Miura origami, a.k.a. two-fold Miura origami, is a variant of a regular Miura origami. The difference between a curved Miura origami and a regular Miura origami lies in the angles φ1 and φ2, as shown in Fig 1, where the solid lines represent mountain fold lines, the dash lines represent valley fold lines, H represents the height of the pattern and l1 and l2 represent the respective side lengths (l1 ≤ l2). In a regular Miura origami, the angle φ1 remains equal to φ2. Otherwise, the pattern is transformed to a curved Miura origami. The unequal φ1 and φ2 make the pattern globally curved and a curved Miura origami-patterned unit can be formed by connecting four pieces of the pattern end to end in order around an axis, once the closure condition given by Eq (1) [25, 26] is satisfied. The formed unit is shown in Fig 2, where α is the fold angle of the pattern.

Fig 1

A regular Miura origami and a curved Miura origami when fully unfolded.

(a) a regular Miura origami (φ1 = φ2); (b) a curved Miura origami (φ1 ≠ φ2).

Fig 2

A unit of a curved Miura origami-patterned tube.

3-level curved Miura origami-patterned tubes

Schemes of fold lines

Rigid origami is an important concept about origami patterns, where the origami folds and unfolds with rigid panels rotating about hinge-like fold lines [27]. The hinge-like lines transfer axial force and shear but moment. Here we call them HL lines. However, in some cases, origami patterns are manufactured by cold forming techniques, including stamping against dies [19], cold gas pressure folding [28], and 3D printing [29]. In those manufacturing methods, materials are continuous at fold lines and the cross section area of materials there are not reduced. In such case, besides shear and axial force, the fold lines transfer moment. Thus, the lines can no longer be considered as frictionless hinges. Here those lines are named CT lines. By setting fold lines of the unit as one of the two types of lines we define above, four arrangement schemes of the lines are developed as shown in Fig 3.

Fig 3

Schemes of fold lines.

Numerical simulation validation

Crash box and the tube studied in this work are both patterned by degree-4 vertices. A test on an origami crash box conducted in Zhou’s work [30] is used to validate the finite element simulation method herein. In the work, a crash box was fixed on a rigid bearing plate and a parallel rigid loading plate moved vertically against the specimen at a rate of 0.83 mm/s, as shown in Fig 4. The specimen was made of 1 mm-thick steel plate at specified minimum yield stress of 235 MPa.

Fig 4

Tested origami crash box.

Universal finite element software package ANSYS/Implicit 18.0 is used to simulate the test process. Measured constitutive relationship of the steel is used for the simulation. Fig 5 presents the finite element modelling method. Element SHELL181, CONTA175 and TARGE170 are adopted and the boundary conditions are consistent with the test. Fig 6 compares the test results and the numerical results. It can be seen that the numerical results are in overall good agreement with the test results. The reason that the simulation exhibits greater initial stiffness is that the modelled crash box gets into perfect contact with the loading plate without any gap at the beginning of loading, while the specimen’s end is imperfectly flat, leading to progressive contact. Severe strain concentration occurs at the vertex where four mountain lines and two valley lines meet in both results. The vertex is marked by a red dash square, where material fracture is most likely to occur. The agreement between the numerical results and the test results indicates the numerical simulation predicts the behavior of the specimen well.

Fig 5

Finite element modelling of crash box.

Fig 6

Comparison between test results and numerical results.

Nonlinear numerical simulations

A curved Miura origami-patterned tube is assembled by vertically stacking three of the units shown in Fig 2. Four tubes are assembled corresponding to the four schemes listed in Fig 3, respectively. Since a given set of the parameters H, l (l1+l2), φ1 and α could determine the geometry of the pattern, identical parameters are adopted for the tubes, as listed in Table 1.

Table 1

Modelling information of patterned tubes.

Tube	Adopted scheme	Geometrical parameters
		H / mm	l (l1+l2) / mm	φ1 / deg	α / deg
C-ORI-1	Scheme 1	400	200	85	135
C-ORI-2	Scheme 2
C-ORI-3	Scheme 3
C-ORI-4	Scheme 4

Nonlinear numerical simulations are conducted using ANSYS/Implicit 18.0, with the purpose to investigate buckling suppression of the schemes in Fig 3. The geometrical model and finite element modelling are detailed in Fig 7. Typical 4-node shell element SHELL181 is employed to simulate the 8 mm-thick panels of the origami pattern and the 20 mm-thick end plates of the tube. The end plates are used to close the hollow cross sections and increase local stability at ends. As a common practice for the connection between a brace and a beam-column joint in building structures, pin ends are used for the tubes. In order to simulate the pin ends, MASS21 element is placed at both ends, connecting nodes of the end plates by MPC184 Rigid Beam elements. In such way, with the constraints at MASS21 elements, rotations about the ends as a whole are allowed. The external load and the reaction force is applied at MASS21 elements. The loading end (the upper end) is allowed to translate in z direction and rotate about x and y directions (UX = UY = ROTZ = 0). The support (the lower end) is allowed to rotate about x and y directions (UX = UY = UZ = ROTZ = 0). For HL lines in the schemes, node coupling of the translational degrees of freedom along the lines are used. Thus, the lines are able to rotate without resistance. The material of the model is hot rolled steel with a 4-segment piecewise linear constitutive relationship [31], which is shown in Fig 8. The material parameters are listed in Table 2, where fy is the yield stress, fu is the ultimate stress, E is the elastic modulus, Est is the slope of strengthening, εy is the yield strain, εst is the strain at the onset of stress strengthening, εu is the strain at the ultimate stress and εel is the ultimate strain. Displacement-controlled loading is applied in the simulation. In order to ensure the reach of a peak point of the load force versus displacement curve, the loading distance is 60 mm (approximately 5.4% of the tube length).

Fig 7

Modelling of a 3-level patterned tube.

Fig 8

Constitutive relationship of steel.

Table 2

Parameters of constitutive relationship of steel.

E / MPa	fy / MPa	fu / MPa	εy / %	εst / %	εu / %	εel / %
206000	260	420	0.13	1.51	5.39	26

Results and discussion

The load force F versus load displacement Δ curves of the tubes are shown in Fig 9, where the axial compressive strain ε is calculated by Eq (2), the effective tube length l0 = 1119 mm, and the peak points are symbolized. Deformation and VonMises stress distribution at the peak points and at the end of loading (Δ = 60 mm) are shown in Figs 10 and 11, respectively. In the figures, it can be seen that the tubes deform in a similar way and magnitude and distribution of the stress does not show much difference. The maximum stress appears at CT lines and the vertex near mid-length. For all the tubes, prior to peak points, just slight lateral deformation is observed and once the peak points are reached, the deformation increases rapidly. At Δ = 60 mm, global buckling of the tubes is significant. Figs 9–11 together demonstrate a discipline of the deformation transformation of the tubes: before the peak points, the deformation modes are governed by axial compression with mild global bending; after the points are reached, a swift in-crease of the lateral deformation is experienced, and the major deformation mode transfers to global flexural buckling, accompanied by substantial capacity loss and consequently the tubes’ instability. Values of displacement at the peak point Δpeak and the corresponding axial compressive strain εpeak are given next to the peak points. It can be found that the values of Δpeak and εpeak of C-ORI-4 are 30.2%, 34.6% and 35.9% larger than those of C-ORI-1, C-ORI-2 and C-ORI-3 respectively, indicating the greatest axial deformation capacity of C-ORI-4 among the tubes.

Fig 9

Load force F versus load displacement Δ curves.

Fig 10

Deformation and stress distribution of tubes at peak points.

(a) C-ORI-1; (b) C-ORI-2; (c) C-ORI-3; (d) C-ORI-4.

Fig 11

Deformation and stress distribution of tubes at Δ = 60 mm.

(a) C-ORI-1; (b) C-ORI-2; (c) C-ORI-3; (d) C-ORI-4.

Consistent with typical simply-supported axially loaded column, the global bending of the patterned tubes is found to be in a semi-sine wave. In order to indicate the magnitude of deviation from the initial straight states, curvature of the deformed tube k is adopted as Eq (3), where θ1 and θ2 are the rotations of the support end and the loading end respectively, as shown in Fig 12(A). Fig 12(B) depicts the values of k during the load process. It can be seen in the figure that for all the tubes the values of k remain small and go up almost linearly as the displacement Δ increases before peak points are arrived, while the increase is much accelerated in the post peak periods. C-ORI-4 is observed to behave the least k among the tubes. Specifically, the maximum rotation of C-ORI-4 are 6.5 degrees and for any given displacement Δ in the load process, the curvature of C-ORI-4 are up to 59.9%, 57.3% and 52.3% less than those of C-ORI-1, C-ORI-2 and C-ORI-3 respectively. The least deviation from the initial straight states indicates the least magnitude of lateral deformation and global buckling of C-ORI-4 among the tubes in the post peak periods. Besides, it is the least curvature that leads to the latest occurrence of global buckling of C-ORI-4 as shown in Fig 9.

Fig 12

Rotations at ends.

(a) illustration of rotations; (b) curvatures during loading process.

Through the observations and discussions above, it is demonstrated that global buckling of C-ORI-4 is suppressed to most extent among the four tubes investigated. Therefore, in light of the same geometry shared by the tubes, Scheme 4, represented by C-ORI-4, is believed to be an effective strategy to suppress global buckling of a curved Miura origami-patterned tube.

Application to a long tube

To extend the work to design of braces in building structures, we apply Scheme 4 to a long tube in this section. Eight units are vertically stacked, increasing the tube length to L0 = 3400 mm. Distinct geometrical configurations are adopted and the parameters are listed in Table 3. The thickness of the steel panel is 8 mm and that of the end plate is 20 mm. The same modelling method is adopted as previously mentioned and is shown in Fig 13.

Table 3

Modelling information of patterned tubes.

Tube	Geometrical parameters
	H / mm	l (l1+l2) / mm	φ1 / deg	α / deg
C-ORI-L-1	200	280	80	120
C-ORI-L-2	200	300	80	120
C-ORI-L-3	200	280	85	135
C-ORI-L-4	220	300	80	120
C-ORI-L-5	220	300	80	135
C-ORI-L-6	240	280	85	105

Fig 13

Modelling of an 8-level patterned tube.

Numerical simulation is conducted on the mechanical behavior of the tubes under axial compression. Table 4 gives the values of Δpeak and εpeak, which indicate occurrence of global buckling. It can be seen in the table that the values of C-ORI-L-1, C-ORI-L-2 and C-ORI-L-4 are substantially larger than the others (up to 6 times as those of the others), indicating that global buckling occurs much later for the three tubes. Deformation and stress distribution of the three tubes at Δpeak and εpeak are presented in Fig 14. It can be observed that the tubes deform axially and hardly bent, with uniformly stress distribution in length at that large axial compressive strain, which is barely found in conventional tubes in civil engineering (straight square and circular long tubes). It demonstrates the superior axial deformation capacity of the tubes to the conventional tubes and proves that Scheme 4 is potentially an effective way to alleviate buckling instability of a long tube when appropriately designed.

Table 4

Values of Δpeak and εpeak.

Tube	Δpeak / mm	εpeak / %
C-ORI-L-1	80.96	2.38
C-ORI-L-2	90.04	2.65
C-ORI-L-3	27.61	0.81
C-ORI-L-4	93.02	2.74
C-ORI-L-5	15.61	0.46
C-ORI-L-6	23.61	0.69

Fig 14

Deformation and stress distribution of tubes at peak points.

(a) C-ORI-L-1; (b) C-ORI-L-2; (c) C-ORI-L-4.

Conclusions

Global buckling suppression is an important issue for energy absorbing tubes, as the buckling alters the deformation mechanism and in turn deteriorates the energy absorption capacity. The present work provides a novel strategy to effectively suppress global buckling of a curved Miura origami-patterned tube by applying a specific scheme of fold lines of the pattern. According to the simulation results, the scheme manages to reduce the lateral deformation in roughly half compared with the counterparts. Conclusions from the work are drawn as follows:

By categorizing the fold lines of curved Miura origami into HL lines and CT lines, different schemes of the octagon patterned tube can be developed. Tubes using the schemes behave distinct lateral deformations under axial compression. By taking advantage of this feature, a superior scheme can be found to achieve the least lateral deformation and the best axial deformation capacity.

Compared with the other fold line schemes, it is found that when the inclined valley lines are considered as HL lines and the others as CT lines, the scheme enables the 3-level tube to reduce the magnitude of lateral deformation by up to 59.9% and to delay the occurrence of global buckling by up to 35.9%. It indicates the excellence of the scheme in global buckling suppression of the patterned tube.

Provided appropriate design, a long patterned tube using the superior scheme can achieve excellent axial deformation capacity under axial compression with substantially delayed global buckling, unnoticeable lateral deformation and uniformly stress distribution in length. The scheme is potentially an effective way to alleviate buckling instability of a long tube.

In follow-up study, the scheme will be parametrically examined on slender tubes and preparation of a physical model will be on schedule.

Original images of Figs 6, 10–12.

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Data behind Fig 9.

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Data behind Fig 12.

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Data behind Table 4.

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9 Mar 2022

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Reviewer #1: This paper presents a novel fold-line scheme for delaying the onset of global buckling in long

Curved Miura tubes. The Curved Miura tubes have an octagonal cross-section and the material

properties of steel. Each mountain and valley crease of these tubes is categorized as either a

hinge-like (HL) or a continuous (CT) fold line. HL lines only transfer the axial and shear forces

in the tube but they do not transfer moments along the crease. Continuous lines maintain the

material properties and thickness and of the tube and can transfer moments in addition to the

axial and shear forces. Four schemes are investigated in this paper: 1. All fold-lines are HL, 2.

All fold-lines are CT, 3. Only horizontal fold-lines are HL, and 4. Only slanted valley creases are

CT. In summary, the authors’ numerical model successfully showed that the different schemes

affect when global buckling is initiated in the tubes and that the fourth scheme appears to provide

the greatest suppression of the global buckling. The reviewer saw the novelty of the work for

Curved Miura tubes. Also, the manuscript is well organized. However, there are a few areas

where clarification and additional justification for the research approach taken is necessary to

fully understand the work. The authors should try to address the following points before the

paper is published:

�  It is not clear why the authors’ selected the Curved Miura architecture for study. Miura

fold patterns are usually utilized for applications concerning deployability due to their

rigid-foldable behavior which, usually does not make them suitable for energy absorption

applications. Other geometries such as Yoshimura, Kresling, variations of square patterns

(including one used for Numerical Verification in this paper) and others have been

investigated by other groups in the past because these geometries can take advantage of

deformations in the facets as well as the creases for energy absorption.

�  Energy absorption tubes usually do not use hinges or other compliant mechanisms. Even

if global buckling can be suppressed through all of compression, can one achieve enough

energy absorption to make Curved Miura with Scheme 4 competitive with other tube

geometries?

�  Are Schemes 1-4 the only ones that can be generated? Could a Scheme 5 include CT

horizontal creases but all other fold line are HL? Are the schemes selected based on their

possible manufacturability?

�  It is skeptical that the test conducted on the crash box from Zhou’s work counts as

numerical validation for this paper. Certain boundary conditions are not compatible with

the Curved Miura tube. Additionally, the Curved Miura tube simulations require node

couplings along creases for Schemes 1, 3, and 4 and all simulations use beams at the ends

of the tubes. Plus, for reasons not quite stated, the ends of the tubes have a greater

thickness than the walls of the tube. Curved Miura is also an entirely different geometry.

More justification should be given for this step.

�  A comment on the choice for the height of the tubes would also be helpful. Although

there is a section of the paper entitled “Application to a Long Tube,” the tubes before this

section are already significantly longer than other pre-folded tubes in many energy

absorption studies. If the tubes with H=400 mm can trigger global buckling and are

already longer than most tubes studied, why is there another section devoted to tubes that

are even longer?

Other comments the authors may find helpful:

�  In the Abstract, there is a sentence that says “delays global buckling by ~36%” but this

number has no context. Is it ~36% compared to some control tube? This also happens in

the Conclusion when it is said that Scheme 4 reduces the lateral deformation “in half.” In

half compared to what?

�  “Unusual” is a strong word to use and is not elaborated upon in the Introduction. What

properties are “unusual”?

�  “Except that” does not work for its respective sentence in the Introduction. Maybe “Also”

could be used instead?

�  “Highly sensitivity” was probably meant to be “High sensitivity”

�  In the Introduction, the work done by Guest and Pellegrino is used as an example of the

Kresling pattern being applied to thin-walled tubes but the work was not conducted for

energy absorption applications. It may be beneficial to add a reference for the research

completed by Professor Ichiro Hagiwara on metal Kresling tubes for energy absorption

applications.

�  In the Materials and Methods section, there is one part that reads “…transfer axial force

and shear but moment.” I think this part is supposed to say “…but not moment.”

�  In Figure 3, why are the horizontal lines at the top and bottom cross-sections categorized?

The reviewer’s understanding is that these are not creases.

�  Why are facets 8mm thick in numerical simulations? Also, what are the dimensions of

l_1 and l_2?

�  In the Results and Discussion, there is one line that reads “…as shown in Fig. 8” but this

figure does not include data. Is this a typo?

�  In the Application to a Long Tube section, “conventional tubes” is used as a term but

how is this defined? Are these straight-walled tubes? Shorter tubes? Other pre-folded

tubes?

Reviewer #2: The work proposes an origami folding pattern to supress global buckling of a thin-walled tube. It is a very interesting and effective concept. There are some minor issues that need to be clarified.

1. "curved Miura pattern" is used. I wonder if here "curved" may be misunderstood as "curved" creases. If this is not a common term, the authors may need to think of another term.

2. In the finite element modelling of a crash box, details of the material properties should be given, in addition to the value of yield stress. Was the actual sress-strain curve used, or was a bi-linear model used, for example.

3. it would be interesting to discuss about tubes of the same/similar cross-sectional dimensions when the effect of patterning was studied. This needs to be mentioned.

4. It was not clear if global buckling was actually supressed or has just been delayed. It would be interesting to see how effectvie the method is for tubes of different lengths.

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Reviewer #1: No

Reviewer #2: No

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22 Apr 2022

Dear Editor and Reviewers,

Thank you for your letter and for the reviewers’ comments concerning our manuscript entitled “Buckling suppression of a thin-walled Miura-origami patterned tube” (ID: PONE-D-21-23372). The comments are valuable and constructive for the improvement of the manuscript, and of significant importance to our research work.

We have revised our manuscript after reading the comments from the reviewers. The revisions include content revisions and language improvement. The revised portions are tracked in the uploaded file labeled ‘Revised Manuscript with Track Changes’. An unmarked version of the revised manuscript labeled ‘Manuscript’ is also uploaded.

The response to the reviewers is uploaded labeled as ‘Response to Reviewers’, which includes figures for explanations.

Lastly, the study’s minimal underlying data set is uploaded as a Supporting Information file.

Best,

Dr. Yangqing Liu & Dr. Jianguo Cai

School of Civil Engineering

Chongqing Jiatong University & Southeast University

Chongqing, P.R.China & Nanjing, Jiangsu, P.R.China

Submitted filename: Response to Reviewers.docx

Click here for additional data file.

7 Jun 2022

Buckling suppression of a thin-walled Miura-origami patterned tube

PONE-D-21-23372R1

Dear Dr. Liu,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Jianguo Wang, PhD

Academic Editor

PLOS ONE

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Comments to the Author

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Reviewer #1: All comments have been addressed

Reviewer #2: All comments have been addressed

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2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

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3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: N/A

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Reviewer #1: Yes

Reviewer #2: Yes

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Reviewer #1: Yes

Reviewer #2: Yes

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6. Review Comments to the Author

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Reviewer #1: (No Response)

Reviewer #2: the authors have addressed my points. the manuscript has been revised accordinly, although it would have been better to incorporate the points in the revision in addition to response part.

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Reviewer #1: No

Reviewer #2: No

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10 Jun 2022

PONE-D-21-23372R1

Buckling suppression of a thin-walled Miura-origami patterned tube

Dear Dr. Liu:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Jianguo Wang

Academic Editor

PLOS ONE