Zhanpeng Tang1, Xirui Zhu1, Yanzhi Li1, Chenghao Qu1, Lin Li1, Shuhai Li1, Lei Qi1, Ming Lu1, Chuanle Cheng1, Hui Tian2. 1. Department of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, People's Republic of China. 2. Department of Thoracic Surgery, Qilu Hospital of Shandong University, Jinan, Shandong, 250012, People's Republic of China. tianhuiql@126.com.
Abstract
BACKGROUND: Enhanced recovery after surgery (ERAS) is a perioperative management protocol to accelerate patient recovery. This study aimed to evaluate the feasibility of ERAS protocols implemented in patients who underwent neoadjuvant chemotherapy (NACT) before minimally invasive McKeown esophagectomy. METHODS: This retrospective study compared the short-term clinical outcomes in esophagectomy patients from June 2018 to June 2021. Subjects were divided into two categories: those who underwent NACT (NACT group) and the non-NACT group. RESULTS: There was no significant difference in total postoperative complication morbidity between the NACT and non-NACT groups (21.2% vs. 20.7%, P=0.936). In addition, the hospital length of stay post-surgery (7.90 vs. 7.71 days, P=0.424) was not significantly longer when compared to the non-NACT group. The time to chest tube removal (5.37 vs. 5.13 days, P=0.238) and first bowel movement (2.92 vs. 3.01 days, P=0.560) was also similar between the two groups. CONCLUSIONS: There was no significant difference in postoperative complications rate, postoperative hospital length of stay, and readmission rate between the two group. This study proved that ERAS protocols seemed to be safe and feasible for patients who received NACT before esophagectomy.
BACKGROUND: Enhanced recovery after surgery (ERAS) is a perioperative management protocol to accelerate patient recovery. This study aimed to evaluate the feasibility of ERAS protocols implemented in patients who underwent neoadjuvant chemotherapy (NACT) before minimally invasive McKeown esophagectomy. METHODS: This retrospective study compared the short-term clinical outcomes in esophagectomy patients from June 2018 to June 2021. Subjects were divided into two categories: those who underwent NACT (NACT group) and the non-NACT group. RESULTS: There was no significant difference in total postoperative complication morbidity between the NACT and non-NACT groups (21.2% vs. 20.7%, P=0.936). In addition, the hospital length of stay post-surgery (7.90 vs. 7.71 days, P=0.424) was not significantly longer when compared to the non-NACT group. The time to chest tube removal (5.37 vs. 5.13 days, P=0.238) and first bowel movement (2.92 vs. 3.01 days, P=0.560) was also similar between the two groups. CONCLUSIONS: There was no significant difference in postoperative complications rate, postoperative hospital length of stay, and readmission rate between the two group. This study proved that ERAS protocols seemed to be safe and feasible for patients who received NACT before esophagectomy.
Authors: Peter P Grimminger; Lucas Goense; Ines Gockel; Damien Bergeat; Nicolas Bertheuil; Servarayan M Chandramohan; Ke-Neng Chen; Seung-Hon Chon; Collet Denis; Khean-Lee Goh; Caroline Gronnier; Jun-Feng Liu; Bernard Meunier; Phillippe Nafteux; Enrique D Pirchi; Marc Schiesser; René Thieme; Aaron Wu; Peter C Wu; Navtej Buttar; Andrew C Chang Journal: Ann N Y Acad Sci Date: 2018-07-08 Impact factor: 5.691
Authors: Kristine Elisabeth Eberhard; Michael Patrick Achiam; Hans Christian Rolff; Mohamed Belmouhand; Lars Bo Svendsen; Morten Thorsteinsson Journal: World J Surg Date: 2017-06 Impact factor: 3.352