Literature DB >> 35879574

Long-term weight loss after bariatric procedures for morbidly obese adolescents and youth: a single-institution analysis with up to 19-year follow-up.

Paul H McClelland1, Krystyna Kabata2, Wojciech Gorecki3, Antalya Jano2, Michael E Zenilman2, Piotr Gorecki2.   

Abstract

BACKGROUND: Obesity is a public health concern among adolescents and young adults. Bariatric surgery is the most effective treatment for morbid obesity and has been increasingly utilized in young patients. Long-term outcomes data for bariatric surgery in this age group are limited.
METHODS: This is a single-institution, prospective analysis of 167 patients aged 15-24 years who underwent one of three laparoscopic bariatric procedures between 2001 and 2019: Roux-en-Y gastric bypass (LRYGB, n = 71), adjustable gastric banding (LAGB, n = 22), and sleeve gastrectomy (LSG, n = 74). Longitudinal weight and body mass index (BMI) measurements were compared to evaluate patterns of weight loss.
RESULTS: All operations were completed laparoscopically using the same clinical pathways. Patients were predominantly female (82.6%), had a median age of 22.0 [Q1-Q3 20.0-23.0] years, and had a mean presurgical BMI of 48.5 ± 6.5 kg/m2 (range 38.4-68.1 kg/m2). All procedures produced significant weight loss by 1 year, peak weight loss by 2 years, and modest weight regain after 5 years. Mean percent weight/BMI losses at 5 years for LRYGB, LAGB, and LSG were - 36.7 ± 10.8%, - 14.5 ± 15.3%, and - 25.1 ± 13.4%, respectively (p < 0.001). LRYGB patients were most likely to achieve ≥ 25% weight loss at 1, 3, and 5 years and maintained significant average weight loss for more than 15 years after surgery. Reoperations were procedure-specific, with LAGB, LRYGB, and LSG having the highest, middle, and lowest reoperation rates, respectively (40.9% vs. 16.9% vs. 5.4%, p < 0.001).
CONCLUSION: All procedures provided significant and durable weight loss. LRYGB patients achieved the best and most sustained weight loss. LSG patients experienced second-best weight loss between 1 and 5 years, with lowest chance of reoperation. LAGB patients had the least weight loss and the highest reoperation rate. Compared to other factors, type of bariatric procedure was independently predictive of successful weight loss over time. More studies with long-term follow-up are needed.
© 2022. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.

Entities:  

Keywords:  Adjustable gastric banding; Bariatric surgery; Roux-en-Y gastric bypass; Sleeve gastrectomy; Weight loss; Youth

Year:  2022        PMID: 35879574     DOI: 10.1007/s00464-022-09434-0

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   3.453


  49 in total

1.  Severe obesity in children and adolescents: identification, associated health risks, and treatment approaches: a scientific statement from the American Heart Association.

Authors:  Aaron S Kelly; Sarah E Barlow; Goutham Rao; Thomas H Inge; Laura L Hayman; Julia Steinberger; Elaine M Urbina; Linda J Ewing; Stephen R Daniels
Journal:  Circulation       Date:  2013-09-09       Impact factor: 29.690

Review 2.  Review of Childhood Obesity: From Epidemiology, Etiology, and Comorbidities to Clinical Assessment and Treatment.

Authors:  Seema Kumar; Aaron S Kelly
Journal:  Mayo Clin Proc       Date:  2017-01-05       Impact factor: 7.616

3.  Improvement in nonalcoholic fatty liver disease and metabolic syndrome in adolescents undergoing bariatric surgery.

Authors:  John J Loy; Heekoung A Youn; Bradley Schwack; Marina Kurian; Christine Ren Fielding; George A Fielding
Journal:  Surg Obes Relat Dis       Date:  2014-11-20       Impact factor: 4.734

4.  Cardiovascular risk factors and excess adiposity among overweight children and adolescents: the Bogalusa Heart Study.

Authors:  David S Freedman; Zuguo Mei; Sathanur R Srinivasan; Gerald S Berenson; William H Dietz
Journal:  J Pediatr       Date:  2007-01       Impact factor: 4.406

Review 5.  ASMBS pediatric metabolic and bariatric surgery guidelines, 2018.

Authors:  Janey S A Pratt; Allen Browne; Nancy T Browne; Matias Bruzoni; Megan Cohen; Ashish Desai; Thomas Inge; Bradley C Linden; Samer G Mattar; Marc Michalsky; David Podkameni; Kirk W Reichard; Fatima Cody Stanford; Meg H Zeller; Jeffrey Zitsman
Journal:  Surg Obes Relat Dis       Date:  2018-03-23       Impact factor: 4.734

Review 6.  Bariatric surgical management of adolescents with morbid obesity.

Authors:  Sean J Barnett
Journal:  Curr Opin Pediatr       Date:  2013-08       Impact factor: 2.856

7.  Health-related quality of life before and after bariatric surgery in adolescents.

Authors:  Tara J Loux; Ramanath N Haricharan; Ronald H Clements; Ronette L Kolotkin; Samuel E Bledsoe; Beverly Haynes; Teresa Leath; Carroll M Harmon
Journal:  J Pediatr Surg       Date:  2008-07       Impact factor: 2.545

8.  Prevalence of Obesity and Severe Obesity in US Children, 1999-2016.

Authors:  Asheley Cockrell Skinner; Sophie N Ravanbakht; Joseph A Skelton; Eliana M Perrin; Sarah C Armstrong
Journal:  Pediatrics       Date:  2018-03       Impact factor: 7.124

9.  Adolescent Bariatric Surgery: Racial Disparities in 30-Day Outcomes Using the MBSAQIP from 2015 to 2018.

Authors:  Allie E Steinberger; Linda M Youngwirth; Se Eun Kim; Naomi N Duke; Asheley Skinner; Alexander Gordee; Maragatha Kuchibhatla; Sarah Armstrong; Keri A Seymour
Journal:  Obes Surg       Date:  2021-05-27       Impact factor: 3.479

Review 10.  Childhood and Adolescent Obesity in the United States: A Public Health Concern.

Authors:  Adekunle Sanyaolu; Chuku Okorie; Xiaohua Qi; Jennifer Locke; Saif Rehman
Journal:  Glob Pediatr Health       Date:  2019-12-01
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