Literature DB >> 35870076

Innovative digital solution supporting sun protection and vitamin D synthesis by using satellite-based monitoring of solar radiation.

Antony R Young1, Sérgio Schalka2, Rowan C Temple3, Emilio Simeone3, Myriam Sohn4, Christina Kohlmann5, Marco Morelli6.   

Abstract

Public health campaigns advise minimising UV radiation (UVR) exposure to prevent skin cancer and precancer, e.g. actinic keratosis (AK). A 3-day clinical field study, in Brazil, was performed to evaluate the mobile app Sun4Health® by siHealth Ltd. The app performs real-time monitoring of both erythemal and vitamin D-effective solar radiation doses using satellite data, enabling personalised recommendations on optimal sun exposure time and sunscreen use. When coupled to a wearable device, the app also provides body-site specific recommendations ("3D" version). 59 healthy volunteers were randomised into 3 groups, each given a different app providing: (1) ultraviolet index only (control app), (2) personalised recommendations and sun overexposure alerts (Sun4Health® app), (3) as (2) but connected via Bluetooth to a wearable device to monitor sun exposure in 3D (Sun4Health®-3D app). Participants were offered sunscreens (SPF 30 and 50) to use at their discretion. Erythema, quantified by reflectance spectroscopy, was assessed daily in the mornings and evenings on six body sites. Serum vitamin D (25(OH)D3) was measured before and after the study. Mean increase of erythema (Mexameter® units ± SD) of all exposed body sites combined over 3 days showed 55.76 ± 47.47 for group 1, 40.27 ± 37.91 for group 2 and 37.12 ± 30.69 for group 3 (p < 0.05 for all groups). Mean increase of serum 25(OH)D3 (nmol/l ± SD) showed 1.32 ± 36.49 for group 1, 6.38 ± 21.19 for group 2 and 18.68 ± 35.45 for group 3 (p > 0.05 for all groups). The results show that the Sun4Health® app is safe to use and can modify behaviour to reduce skin erythema (sunburn) yet not decreasing vitamin D status.
© 2022. The Author(s), under exclusive licence to European Photochemistry Association, European Society for Photobiology.

Entities:  

Keywords:  Actinic keratosis; App; Clinical field study; Erythema; Personalised recommendations; Skin cancer; Sun protection; Vitamin D; Wearable

Year:  2022        PMID: 35870076     DOI: 10.1007/s43630-022-00263-7

Source DB:  PubMed          Journal:  Photochem Photobiol Sci        ISSN: 1474-905X            Impact factor:   4.328


  23 in total

1.  Ultraviolet radiation-induced erythema in human skin.

Authors:  Graham I Harrison; Antony R Young
Journal:  Methods       Date:  2002-09       Impact factor: 3.608

2.  Brazilian consensus on photoprotection.

Authors:  Sérgio Schalka; Denise Steiner; Flávia Naranjo Ravelli; Tatiana Steiner; Aripuanã Cobério Terena; Carolina Reato Marçon; Eloisa Leis Ayres; Flávia Alvim Sant'anna Addor; Helio Amante Miot; Humberto Ponzio; Ida Duarte; Jane Neffá; José Antônio Jabur da Cunha; Juliana Catucci Boza; Luciana de Paula Samorano; Marcelo de Paula Corrêa; Marcus Maia; Nilton Nasser; Olga Maria Rodrigues Ribeiro Leite; Otávio Sergio Lopes; Pedro Dantas Oliveira; Renata Leal Bregunci Meyer; Tânia Cestari; Vitor Manoel Silva dos Reis; Vitória Regina Pedreira de Almeida Rego
Journal:  An Bras Dermatol       Date:  2014 Nov-Dec       Impact factor: 1.896

3.  The effect of sunscreen on vitamin D: a review.

Authors:  R E Neale; S R Khan; R M Lucas; M Waterhouse; D C Whiteman; C M Olsen
Journal:  Br J Dermatol       Date:  2019-07-09       Impact factor: 9.302

4.  Ultraviolet radiation and the skin: Photobiology and sunscreen photoprotection.

Authors:  Antony R Young; Joël Claveau; Ana Beatris Rossi
Journal:  J Am Acad Dermatol       Date:  2016-12-27       Impact factor: 11.527

5.  Melanin has a Small Inhibitory Effect on Cutaneous Vitamin D Synthesis: A Comparison of Extreme Phenotypes.

Authors:  Antony R Young; Kylie A Morgan; Tak-Wai Ho; Ngozi Ojimba; Graham I Harrison; Karl P Lawrence; Nihull Jakharia-Shah; Hans Christian Wulf; J Kennedy Cruickshank; Peter A Philipsen
Journal:  J Invest Dermatol       Date:  2019-12-26       Impact factor: 8.551

6.  Melanin distribution in human epidermis affords localized protection against DNA photodamage and concurs with skin cancer incidence difference in extreme phototypes.

Authors:  Damilola Fajuyigbe; Su M Lwin; Brian L Diffey; Richard Baker; Desmond J Tobin; Robert P E Sarkany; Antony R Young
Journal:  FASEB J       Date:  2018-02-02       Impact factor: 5.191

7.  Sunscreen applied at ≥ 2 mg cm-2 during a sunny holiday prevents erythema, a biomarker of ultraviolet radiation-induced DNA damage and suppression of acquired immunity.

Authors:  J Narbutt; P A Philipsen; G I Harrison; K A Morgan; K P Lawrence; K A Baczynska; K Grys; M Rogowski-Tylman; I Olejniczak-Staruch; A Tewari; M Bell; C O'Connor; H C Wulf; A Lesiak; A R Young
Journal:  Br J Dermatol       Date:  2018-12-05       Impact factor: 9.302

8.  Does Incident Solar Ultraviolet Radiation Lower Blood Pressure?

Authors:  Richard B Weller; Yuedong Wang; Jingyi He; Franklin W Maddux; Len Usvyat; Hanjie Zhang; Martin Feelisch; Peter Kotanko
Journal:  J Am Heart Assoc       Date:  2020-02-28       Impact factor: 5.501

Review 9.  Sunscreen photoprotection and vitamin D status.

Authors:  T Passeron; R Bouillon; V Callender; T Cestari; T L Diepgen; A C Green; J C van der Pols; B A Bernard; F Ly; F Bernerd; L Marrot; M Nielsen; M Verschoore; N G Jablonski; A R Young
Journal:  Br J Dermatol       Date:  2019-07-15       Impact factor: 9.302

10.  Optimal sunscreen use, during a sun holiday with a very high ultraviolet index, allows vitamin D synthesis without sunburn.

Authors:  A R Young; J Narbutt; G I Harrison; K P Lawrence; M Bell; C O'Connor; P Olsen; K Grys; K A Baczynska; M Rogowski-Tylman; H C Wulf; A Lesiak; P A Philipsen
Journal:  Br J Dermatol       Date:  2019-05-24       Impact factor: 9.302

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