Kwang Jin Ko1, Jihyun Lim2, Jiwoong Yu3, Danbee Kang2,4, Juhee Cho2,4, Kyu-Sung Lee5,6. 1. Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea. 2. Center for Clinical Epidemiology, Samsung Medical Center, Seoul, Republic of Korea. 3. Department of Urology, Armed Forces Pocheon Hospital, Pocheon, Republic of Korea. 4. Department of Clinical Research Design and Evaluation, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea. 5. Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Korea. ksleedr@skku.edu. 6. Research Institute for Future Medicine Samsung Medical Center, Seoul, Korea. ksleedr@skku.edu.
Abstract
PURPOSE: Interstitial cystitis/bladder pain syndrome (IC/BPS) has a negative impact on quality of life. We compared health-related quality of life (HRQoL) of patients with IC/BPS with patients having other diseases using the EuroQol five-dimension (EQ-5D) and evaluated whether the HRQoL is improved after surgery. METHODS: We compared EQ-5D of patients with Hunner lesion type IC/BPS with patients who had other diseases that cause chronic and severe pain including arthritis and cancer from a cross-sectional analysis of responses to the 2012-2016 Korea National Health and Nutrition Examination Survey. Changes in EQ-5D after transurethral coagulation (TUC) or resection (TUR) were measured in the IC/BPS participants. RESULTS: Compared to the EQ-5D index of normal population, patients with arthritis, cancer and IC/BPS had - 0.07 (95% CI - 0.07, - 0.06), - 0.01 (95% CI - 0.02, - 0.01), and - 0.21 (95% CI - 0.23, - 0.20) lower scores, respectively. Patients with IC/BPS were 35.9, 9.24, and 9.05 times more likely to have "extreme problem" in pain/discomfort, anxiety/depression, and usual activities EQ-5D domains, respectively, than patients without arthritis/cancer. After TUC or TUR, EQ-5D index was 0.90 in the TUC group and 0.92 in the TUR group. CONCLUSION: IC/BPS patients have worse HRQoL than healthy individuals. However, after surgical treatment, HRQoL is restored to a level close to normal.
PURPOSE: Interstitial cystitis/bladder pain syndrome (IC/BPS) has a negative impact on quality of life. We compared health-related quality of life (HRQoL) of patients with IC/BPS with patients having other diseases using the EuroQol five-dimension (EQ-5D) and evaluated whether the HRQoL is improved after surgery. METHODS: We compared EQ-5D of patients with Hunner lesion type IC/BPS with patients who had other diseases that cause chronic and severe pain including arthritis and cancer from a cross-sectional analysis of responses to the 2012-2016 Korea National Health and Nutrition Examination Survey. Changes in EQ-5D after transurethral coagulation (TUC) or resection (TUR) were measured in the IC/BPS participants. RESULTS: Compared to the EQ-5D index of normal population, patients with arthritis, cancer and IC/BPS had - 0.07 (95% CI - 0.07, - 0.06), - 0.01 (95% CI - 0.02, - 0.01), and - 0.21 (95% CI - 0.23, - 0.20) lower scores, respectively. Patients with IC/BPS were 35.9, 9.24, and 9.05 times more likely to have "extreme problem" in pain/discomfort, anxiety/depression, and usual activities EQ-5D domains, respectively, than patients without arthritis/cancer. After TUC or TUR, EQ-5D index was 0.90 in the TUC group and 0.92 in the TUR group. CONCLUSION: IC/BPS patients have worse HRQoL than healthy individuals. However, after surgical treatment, HRQoL is restored to a level close to normal.
Authors: Sandra H Berry; Marc N Elliott; Marika Suttorp; Laura M Bogart; Michael A Stoto; Paul Eggers; Leroy Nyberg; J Quentin Clemens Journal: J Urol Date: 2011-06-16 Impact factor: 7.450
Authors: Anne M Suskind; Sandra H Berry; Marika J Suttorp; Marc N Elliott; Ron D Hays; Brett A Ewing; J Quentin Clemens Journal: Qual Life Res Date: 2012-10-07 Impact factor: 4.147
Authors: A P M S Romão; R Gorayeb; G S Romão; O B Poli-Neto; F J C dos Reis; J C Rosa-e-Silva; A A Nogueira Journal: Int J Clin Pract Date: 2009-05 Impact factor: 2.503
Authors: J Curtis Nickel; Dean A Tripp; Michel Pontari; Robert Moldwin; Robert Mayer; Lesley K Carr; Raggi Doggweiler; Claire C Yang; Nagendra Mishra; Jorgen Nordling Journal: J Urol Date: 2010-01 Impact factor: 7.450
Authors: Margaux Evenepoel; Vincent Haenen; Tom De Baerdemaecker; Mira Meeus; Nele Devoogdt; Lore Dams; Sophie Van Dijck; Elien Van der Gucht; An De Groef Journal: J Pain Symptom Manage Date: 2021-09-24 Impact factor: 3.612