| Literature DB >> 35867242 |
Cosette Rebouissou1, Séphora Sallis1,2, Thierry Forné3.
Abstract
Many population-based methods investigating chromatin dynamics and organization in eukaryotes are based on the chromosome conformation capture (3C) method. Here, we provide an updated version of the quantitative 3C (3C-qPCR) protocol for improved and simplified quantitative analyses of intra-chromosomal contacts.Entities:
Keywords: Chromatin dynamics and organization; Chromosome conformation capture; Eukaryotic genome; Interaction frequency; Quantitative PCR
Mesh:
Substances:
Year: 2022 PMID: 35867242 DOI: 10.1007/978-1-0716-2497-5_1
Source DB: PubMed Journal: Methods Mol Biol ISSN: 1064-3745