Literature DB >> 3586177

Establishment of a new prostatic carcinoma cell line (TSU-Pr1).

T Iizumi, T Yazaki, S Kanoh, I Kondo, K Koiso.   

Abstract

A new epithelial cell line, TSU-Pr1, from a human prostatic adenocarcinoma metastatic to lymph node has been established in long term tissue culture. The cultured cells show loss of contact inhibition, rapid growth in vitro and growth in athymic nude mice. Karyotypic analysis demonstrated an aneuploid karyotype with a modal chromosome number of 80 including a Y-chromosome and at least 10 marker chromosomes. The cells produced only a small amount of prostatic acid phosphatase, and heterotransplanted tumors did not have nuclear androgen receptors.

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Year:  1987        PMID: 3586177     DOI: 10.1016/s0022-5347(17)44488-0

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  19 in total

1.  DNA-binding sequence of the human prostate-specific homeodomain protein NKX3.1.

Authors:  D J Steadman; D Giuffrida; E P Gelmann
Journal:  Nucleic Acids Res       Date:  2000-06-15       Impact factor: 16.971

2.  Treatment of human prostate tumors PC-3 and TSU-PR1 with standard and investigational agents in SCID mice.

Authors:  L Polin; F Valeriote; K White; C Panchapor; S Pugh; J Knight; P LoRusso; M Hussain; E Liversidge; N Peltier; T Golakoti; G Patterson; R Moore; T H Corbett
Journal:  Invest New Drugs       Date:  1997       Impact factor: 3.850

Review 3.  The human prostatic carcinoma cell line LNCaP and its derivatives. An overview.

Authors:  G J van Steenbrugge; M Groen; J W van Dongen; J Bolt; H van der Korput; J Trapman; M Hasenson; J Horoszewicz
Journal:  Urol Res       Date:  1989

4.  Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assembly.

Authors:  Michael Rosenberg; Shoshana Ravid
Journal:  Mol Biol Cell       Date:  2006-01-04       Impact factor: 4.138

5.  Upregulated MT1-MMP/TIMP-2 axis in the TSU-Pr1-B1/B2 model of metastatic progression in transitional cell carcinoma of the bladder.

Authors:  Christine L Chaffer; Bonnie Dopheide; Daniel R McCulloch; Allan B Lee; Jane M Moseley; Erik W Thompson; Elizabeth D Williams
Journal:  Clin Exp Metastasis       Date:  2005       Impact factor: 5.150

6.  Cytogenetic characterization of several androgen responsive and unresponsive sublines of the human prostatic carcinoma cell line LNCaP.

Authors:  J J König; E Kamst; A Hagemeijer; J C Romijn; J Horoszewicz; F H Schröder
Journal:  Urol Res       Date:  1989

7.  A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49.

Authors:  Lawrence D True; Kent Buhler; Janna Quinn; Emily Williams; Peter S Nelson; Nigel Clegg; Jill A Macoska; Thomas Norwood; Alvin Liu; William Ellis; Paul Lange; Robert Vessella
Journal:  Am J Pathol       Date:  2002-08       Impact factor: 4.307

8.  Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis.

Authors:  W H Lee; R A Morton; J I Epstein; J D Brooks; P A Campbell; G S Bova; W S Hsieh; W B Isaacs; W G Nelson
Journal:  Proc Natl Acad Sci U S A       Date:  1994-11-22       Impact factor: 11.205

9.  Neuroendocrine differentiation in human prostatic tumor models.

Authors:  M A Noordzij; W M van Weerden; C M de Ridder; T H van der Kwast; F H Schröder; G J van Steenbrugge
Journal:  Am J Pathol       Date:  1996-09       Impact factor: 4.307

Review 10.  Growth factors and their receptors as determinants in the proliferation and metastasis of human prostate cancer.

Authors:  J L Ware
Journal:  Cancer Metastasis Rev       Date:  1993-09       Impact factor: 9.264

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