Literature DB >> 35860707

Case Report: Clinical Presentation of Toad Venom-Induced Cardiac Intoxication.

Chia-Yi Lu1, Yung-Yih Chang2, Tzu-Heng Hsu2, Chih-Yun Yeh2, Pei-Fang Lai2.   

Abstract

Six people made the mistake of eating toad soup, and one of them died before arriving hospital. Five patients presented conscious change, gastrointestinal upset, or bradycardia. We checked their blood and electrocardiography to monitor the cardiac intoxication from toad venom. This experience revealed that the serum level of digoxin does not indicate the severity of intoxication but has the diagnostic value. And, serum potassium level is useful to provide valuable therapeutic information.

Entities:  

Keywords:  cardiac intoxication ; digoxin ; potassium ; toad venom

Year:  2022        PMID: 35860707      PMCID: PMC9283113          DOI: 10.6705/j.jacme.202206_12(2).0005

Source DB:  PubMed          Journal:  J Acute Med        ISSN: 2211-5587


  9 in total

Review 1.  Cardiac glycoside toxicity: more than 200 years and counting.

Authors:  Salmaan Kanji; Robert D MacLean
Journal:  Crit Care Clin       Date:  2012-08-30       Impact factor: 3.598

2.  Treatment of toad venom poisoning with digoxin-specific Fab fragments.

Authors:  J R Brubacher; P R Ravikumar; T Bania; M B Heller; R S Hoffman
Journal:  Chest       Date:  1996-11       Impact factor: 9.410

3.  Comparison of toad venoms from different Bufo species by HPLC and LC-DAD-MS/MS.

Authors:  Huimin Gao; Martin Zehl; Alexander Leitner; Xiyan Wu; Zhimin Wang; Brigitte Kopp
Journal:  J Ethnopharmacol       Date:  2010-07-14       Impact factor: 4.360

4.  Bufadienolides from parotoid gland secretions of Cuban toad Peltophryne fustiger (Bufonidae): Inhibition of human kidney Na(+)/K(+)-ATPase activity.

Authors:  Wilmer H Perera Córdova; Suzana Guimarães Leitão; Geraldino Cunha-Filho; Roberto Alonso Bosch; Isel Pascual Alonso; Rogelio Pereda-Miranda; Rodrigo Gervou; Natália Araújo Touza; Luis Eduardo M Quintas; François Noël
Journal:  Toxicon       Date:  2015-11-23       Impact factor: 3.033

Review 5.  Novel therapeutic applications of cardiac glycosides.

Authors:  Ioannis Prassas; Eleftherios P Diamandis
Journal:  Nat Rev Drug Discov       Date:  2008-10-24       Impact factor: 84.694

6.  Toad venom poisoning: resemblance to digoxin toxicity and therapeutic implications.

Authors:  R M Gowda; R A Cohen; I A Khan
Journal:  Heart       Date:  2003-04       Impact factor: 5.994

Review 7.  Management of digoxin toxicity.

Authors:  Matthew Pincus
Journal:  Aust Prescr       Date:  2016-02-01

Review 8.  Management of yellow oleander poisoning.

Authors:  Senaka Rajapakse
Journal:  Clin Toxicol (Phila)       Date:  2009-03       Impact factor: 4.467

Review 9.  The Development of Toad Toxins as Potential Therapeutic Agents.

Authors:  Ji Qi; Abu Hasanat Md Zulfiker; Chun Li; David Good; Ming Q Wei
Journal:  Toxins (Basel)       Date:  2018-08-20       Impact factor: 4.546

  9 in total

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