| Literature DB >> 35857325 |
Andrew Fenelon1, Kasia J Lipska2, Whitney Denary3, Kim M Blankenship4, Penelope Schlesinger3, Denise Esserman5, Danya E Keene3.
Abstract
Importance: Programs that provide affordable and stable housing, such as federal rental assistance, may be associated with improved mean blood glucose levels and related diabetes outcomes. Objective: To assess whether 2 different types of federal rental assistance programs are associated with glycated hemoglobin A1c (HbA1c) levels among middle-aged and older US adults. Design, Setting, and Participants: This cohort study used data from the National Health and Nutrition Examination Survey (NHANES) linked with US Department of Housing and Urban Development records of rental assistance participation. Adults aged 45 years or older who were receiving 2 types of rental assistance (project-based housing or housing vouchers) at the time of the NHANES interview and those who would receive rental assistance within the subsequent 2 years (waitlist group) were included. Data were collected from January 1999 to December 2016 and analyzed in October 2021. Exposures: Rental assistance participation, including project-based housing (subsidized housing developments including public housing) and housing vouchers (tenant-based subsidies for private market housing). Main Outcomes and Measures: The primary outcome was continuous HbA1c level, a common measure of blood glucose reflecting diabetes control. Linear regression was used to estimate the association between the 2 rental assistance programs and HbA1c level. Logistic regression was used to assess the association between rental assistance programs and HbA1c cut points (prediabetes: 5.7% to ≤6.5%; diabetes: >6.5%; uncontrolled diabetes: ≥9% [to convert to proportion of total Hb, multiply by 0.01]). Analyses used weights created by the National Center for Health Statistics that adjust for linkage eligibility.Entities:
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Year: 2022 PMID: 35857325 PMCID: PMC9301513 DOI: 10.1001/jamanetworkopen.2022.22385
Source DB: PubMed Journal: JAMA Netw Open ISSN: 2574-3805
Descriptive Characteristics of 1050 Participants in the NHANES-HUD Sample by Linked Data File Rental Assistance Status From 1999 to 2016
| Characteristic | Participants, % | ||
|---|---|---|---|
| Current rental assistance (n = 795) | Waitlist (n = 255) | ||
| Rental assistance program | |||
| Project-based housing | 51.7 | 66.2 | .002 |
| Vouchers | 48.3 | 33.8 | |
| Sex | |||
| Female | 71.7 | 65.0 | .17 |
| Male | 28.3 | 35.0 | |
| Age group, y | |||
| 45-64 | 57.8 | 60.2 | .62 |
| ≥65 | 42.2 | 39.8 | |
| Race and ethnicity | |||
| Hispanic | 15.5 | 11.7 | .02 |
| Non-Hispanic | |||
| Black | 36.4 | 36.5 | |
| White | 40.3 | 49.8 | |
| Other | 7.8 | 2.0 | |
| Educational level | |||
| Less than high school | 47.4 | 40.9 | .29 |
| High school | 25.3 | 30.4 | |
| Some college | 20.8 | 24.4 | |
| Bachelor’s degree | 6.6 | 4.3 | |
| Family income-to-poverty ratio, % FPL | |||
| <50 | 12.8 | 6.7 | .01 |
| 50 to <100 | 43.3 | 37.1 | |
| 100 to <200 | 33.9 | 40.2 | |
| ≥200 | 4.8 | 9.7 | |
| Missing | 5.2 | 6.3 | |
| HbA1c level, % | |||
| <5.7 | 43.9 | 48.2 | .45 |
| 5.7 to <6.5 | 35.2 | 33.2 | |
| 6.5 to <9.0 | 16.1 | 12.4 | |
| ≥9.0 | 4.8 | 6.2 | |
Abbreviations: FPL, federal poverty level; HbA1c, glycated hemoglobin A1c; HUD, US Department of Housing and Urban Development; NHANES, National Health and Nutrition Examination Survey.
SI conversion factor: To convert HbA1c to the proportion of total Hb, multiply by 0.01.
The sample was limited to adults aged 45 years or older who received rental assistance at some point during the observation period from 1999 to 2016. Values are weighted to account for eligibility for NHANES-HUD linkage.
Receiving rental assistance at the time of the NHANES interview.
Not receiving assistance at the time of the NHANES interview but would enter assistance within 2 years of the interview.
P values shown are for a χ2 test of the difference between current recipients and individuals in the waitlist group.
Other included individuals of all other races and ethnicities; specific categories were not collected by the NHANES.
Hemoglobin A1c is a common measure of blood glucose used to diagnose diabetes. An HbA1c level of 5.7% to 6.5% corresponds to prediabetes, greater than 6.5% to diabetes, and 9.0% or greater to uncontrolled diabetes.
Linear Regression Models of HbA1c Levels as a Function of the Interactions of Project-Based Housing Assistance With Participants’ Sex and Race and Ethnicity
| Model 1 (n = 615) | Model 2 (n = 615) | |||
|---|---|---|---|---|
| β (95% CI) | β (95% CI) | |||
| Currently receiving rental assistance | −0.454 (−0.945 to 0.037) | .07 | −0.599 (−1.132 to −0.065) | .03 |
| Female | −0.237 (−0.753 to 0.280) | .36 | NA | NA |
| Race and ethnicity | ||||
| Hispanic | NA | NA | −0.934 (−1.662 to −0.206) | .01 |
| Non-Hispanic White | NA | NA | −0.800 (−1.400 to −0.200) | .01 |
| Other | NA | NA | −0.820 (−1.713 to 0.074) | .07 |
| Interactions | ||||
| Female × current assistance | 0.253 (−0.391 to 0.897) | .43 | NA | NA |
| Hispanic × current assistance | NA | NA | 0.749 (−0.165 to 1.663) | .11 |
| White × current assistance | NA | NA | 0.380 (−0.324 to 1.084) | .28 |
| Other race and ethnicity × current assistance | NA | NA | 0.778 (−0.200 to 1.756) | .12 |
Abbreviations: HbA1c, glycated hemoglobin A1c; HUD, US Department of Housing and Urban Development; NA, not applicable; NHANES, National Health and Nutrition Examination Survey.
Linked data from NHANES and HUD from 1999 to 2016 were used. Models assessed interactions with continuous HbA1c levels among adults aged 45 years or older. All models accounted for the complex survey design of NHANES, were weighted to reflect eligibility for linkage to the HUD record, and were adjusted for individual and family covariates (sex, age, race and ethnicity, educational level, and family income-to-poverty ratio), NHANES survey year cycle, and state of residence.
Model 1 included an interaction between rental assistance status and sex. The main effect for current assistance in model 1 refers to males, the reference group.
Model 2 included an interaction between rental assistance status and race and ethnicity. The main effect for current assistance in model 2 refers to non-Hispanic Black adults, the reference group.
Other included individuals of all other races and ethnicities; specific categories were not collected by the NHANES.
Mean Marginal Associations of Project-Based Rental Assistance With Dichotomous HbA1c Level Cutoffs
| Difference, percentage points (95% CI) | |||
|---|---|---|---|
| HbA1c level 5.7% to ≤6.5% (n = 615) | HbA1c level >6.5% (n = 615) | HbA1c level ≥9.0% (n = 615) | |
| Currently receiving rental assistance | −3.9 (−14.7 to 6.8) | −3.4 (−14.4 to 7.6) | −3.7 (−7.0 to −0.0) |
| Reference group mean of dependent variable | 55.8 | 22.1 | 6.9 |
Abbreviations: HbA1c, glycated hemoglobin A1c; HUD, US Department of Housing and Urban Development; NHANES, National Health and Nutrition Examination Survey.
SI conversion factor: To convert HbA1c to the proportion of total Hb, multiply by 0.01.
Linked data from NHANES and HUD from 1999 to 2016 were used. Values indicate the mean percentage point difference in the probability of being above the HbA1c cutoff when receiving current assistance vs being in the waitlist group. All models accounted for the complex survey design of NHANES, were weighted to reflect eligibility for linkage to the HUD record, and were adjusted for individual and family covariates (sex, age, race and ethnicity, educational level, and family income-to-poverty ratio), NHANES survey year cycle, and state of residence. An HbA1c level of 5.7% to 6.5% corresponds to prediabetes, greater than 6.5% to diabetes, and 9.0% or greater to uncontrolled diabetes.
P < .05.