Literature DB >> 35857084

Major change in morphology of the talofibular ligaments during fetal development and growth.

Ji Hyun Kim1, Zhe-Wu Jin2, Shogo Hayashi3, Gen Murakami4, José Francisco Rodríguez-Vázquez5, Hiroshi Abe6.   

Abstract

BACKGROUND AND
PURPOSE: Ankle sprain is often attributed to damage of the anterior and posterior talofibular ligaments (ATFL, PTFL). We compared the morphology of these ligaments in fetuses of different gestational ages (GAs) with the horizontal configuration in adults.
MATERIALS AND METHODS: Histological sections of unilateral ankles were examined in 22 fetuses, 10 at GA of 9-12 weeks and 12 at GA of 26-39 weeks.
RESULTS: At a GA of 9 to 10 weeks, the ATFL and PTFL consisted of horizontally running straight fibers. The initial ATFL appeared as a thickening of the capsule of the talocrural joint, although the initial PTFL was distant from this joint. Until a GA of 12 weeks, the talus and fibula were separated by an expanding joint cavity. Thus, the initial horizontal ligaments were "pulled" in a distal direction. The distal parts of the ligaments consisted of thin collagenous fibers that had an irregular array, whereas the short proximal parts had thick fibers and a horizontal array. In near-term fetuses, the ligaments contained no horizontal fibers. The ATFL had a wavy course around the thick synovial fold, and was exposed to the joint cavity along the entire course; the distal part was thinner than the proximal part. The PTFL was bulky and consisted of fibers with an irregular array. Therefore, the morphology in a near-term fetus was quite different from that in adults.
CONCLUSION: The horizontal and straight composite ankle fibers in adults apparently result from postnatal reconstruction, depending on mechanical demand.
© 2022. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.

Entities:  

Keywords:  Ankle sprain; Composite collagenous fibers; Human fetuses; Talofibular ligaments

Mesh:

Year:  2022        PMID: 35857084     DOI: 10.1007/s00276-022-02987-8

Source DB:  PubMed          Journal:  Surg Radiol Anat        ISSN: 0930-1038            Impact factor:   1.354


  13 in total

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Authors:  D J GRAY; E GARDNER
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Authors:  J A Mérida-Velasco; I Sánchez-Montesinos; J Espín-Ferra; J R Mérida-Velasco; J F Rodríguez-Vázquez; J Jiménez-Collado
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7.  Number of fiber bundles in the fetal anterior talofibular ligament.

Authors:  Mutsuaki Edama; Tomoya Takabayashi; Hirotake Yokota; Ryo Hirabayashi; Chie Sekine; Sae Maruyama; Mayuu Syagawa; Ryoya Togashi; Yuki Yamada; Hiroki Otani
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9.  Lateral ligament injury of the ankle and associated articular cartilage degeneration in the talocrural joint: anatomic study using elderly cadavers.

Authors:  Kazuya Hirose; Gen Murakami; Takeshi Minowa; Hideji Kura; Toshihiko Yamashita
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10.  Ultrasound anatomy in the normal neonatal and infant foot: an anatomic introduction to ultrasound assessment of foot deformities.

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