A follow-up study of platelet-rich plasma serotonin in clinical subtypes of cerebral infarction.

The serotonin concentration in the platelet-rich plasma of 32 patients with single and multiple stroke type cerebral infarction was investigated at various stages. Serotonin levels were decreased in the acute period. The incidence of serotonin abnormality was higher in multiple types than in the single type. Serotonin levels were significantly decreased in treated hypertensive patients compared with untreated patients. Serotonin levels, therefore, varied according to the type and stage of cerebral infarction.