Literature DB >> 35846929

A long-standing case of desmoplastic fibroblastoma of the face.

Arpita Singh1, Snehashish Ghosh2, Satyapriya Shivakotee3, Safal Dhungel4, A Thirumal Raj5, Shankargouda Patil6.   

Abstract

The present case report depicts an unusually large desmoplastic fibroblastoma. The diagnosis of the lesion appears to be deceptive clinically. The purpose of this case image is to highlight its size and presenting symptoms, which could easily be mistaken for an odontogenic, salivary gland, or a soft tissue neoplasm.
© 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

Entities:  

Keywords:  benign; desmoplastic; female; fibroblastoma

Year:  2022        PMID: 35846929      PMCID: PMC9272213          DOI: 10.1002/ccr3.6029

Source DB:  PubMed          Journal:  Clin Case Rep        ISSN: 2050-0904


INTRODUCTION

Evans et al. in 1995 described desmoplastic fibroblastoma (DF) as a benign soft tissue tumor. Based on the histopathological observation of Neilsen et al., the term collagenous fibroma was suggested for DF.

CASE PRESENTATION

A 50‐year‐old woman reported to the outpatient department of Oral and Maxillofacial Surgery with a chief complaint of facial swelling for around 13 years. Following examination, a soft tissue swelling measuring (10x9x2) cm was noted on the left side of the face (Figures 1A,B). The swelling was firm and nontender, and the overlying skin was normal.
FIGURE 1

(A) Preoperative frontal view of the patient. (B) Preoperative lateral view of the patient. (C) Photomicrograph showing hypocellular areas with fibroblastic and myofibroblastic proliferation (200× magnification)

(A) Preoperative frontal view of the patient. (B) Preoperative lateral view of the patient. (C) Photomicrograph showing hypocellular areas with fibroblastic and myofibroblastic proliferation (200× magnification)

DIAGNOSIS

Microscopic examination from the most dependent part of the lesion revealed a nonencapsulated lesional tissue consisting of proliferation of spindle‐ and stellate‐shaped fibroblasts with large oval nuclei and bi‐ or trinucleation, immersed in the abundant dense collagenous stroma (Figures 1C).

MANAGEMENT

Treatment included a wide local excision of the lesion and primary closure under general anesthesia. Following treatment, the patient was observed for 48 hours and then discharged. Postoperative view of the patient is depicted in Figure 2. The patient did not report back for follow‐up. Take‐home message is that whenever such a case is encountered, this entity should be considered one of the differential diagnoses. Histopathology is mandatory before the formulation of a treatment plan to ensure the correct treatment is rendered to the patient.
FIGURE 2

Postoperative view of the patient

Postoperative view of the patient

AUTHOR CONTRIBUTIONS

All the authors contributed to the writing of the manuscript.

CONFLICT OF INTEREST

None.

ETHICAL APPROVAL

Ethical approval was not required from the institution, in accordance with our country's law, as this was a case report.

CONSENT

Written informed consent was obtained from the patient to publish this case image in accordance with the journal's patient consent policy.
  2 in total

1.  Collagenous fibroma (desmoplastic fibroblastoma): a report of seven cases.

Authors:  G P Nielsen; J X O'Connell; G R Dickersin; A E Rosenberg
Journal:  Mod Pathol       Date:  1996-07       Impact factor: 7.842

2.  Desmoplastic fibroblastoma. A report of seven cases.

Authors:  H L Evans
Journal:  Am J Surg Pathol       Date:  1995-09       Impact factor: 6.394

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.