| Literature DB >> 35838968 |
Fatemeh Zahedipour1,2, Paul C Guest3, Muhammed Majeed4, Seyed Adel Moallem5,6, Prashant Kesharwani7, Tannaz Jamialahmadi8, Amirhossein Sahebkar9,10,11,12.
Abstract
SARS-CoV-2 can stimulate the expression of various inflammatory cytokines and induce the cytokine storm in COVID-19 patients leading to multiple organ failure and death. Curcumin as a polyphenolic compound has been shown to have anti-inflammatory properties and inhibit the release of numerous pro-inflammatory cytokines. We present multiplex analysis using the Evidence Investigator biochip system to determine the effect of curcumin on serum level of cytokines which are typically elevated in cytokine storm events, including tumor necrosis factor (TNF-α), interleukin 6 (IL-6), and IL-10.Entities:
Keywords: COVID-19; Curcumin; IL-6; Multiplex analysis; SARS-CoV-2; TNF-α; and IL-10
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Year: 2022 PMID： 35838968 DOI： 10.1007/978-1-0716-2395-4_21
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745