V Z Drumond1, A A Andrade2, J A A de Arruda3, R A Mesquita3, L G Abreu4. 1. School of Dentistry, Faculdade Pitágoras de Ipatinga, Ipatinga, Minas Gerais, Brazil. victorzanettiemc@gmail.com. 2. School of Dentistry, Faculdade Pitágoras de Belo Horizonte, Belo Horizonte, Minas Gerais, Brazil. 3. Department of Oral Surgery, Pathology and Clinical Dentistry, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. 4. Department of Child and Adolescent Oral Health, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Abstract
BACKGROUND: This systematic review and meta-analysis aimed to answer the following question: Are children and adolescents with attention deficit hyperactivity disorder (ADHD) more likely to have gingival or periodontal disease-related outcomes than their non-ADHD peers? METHODS: Searches were conducted in the following databases: Embase, Scopus, Web of Science, and PubMed. Google Scholar and OpenGrey were also verified. Observational studies were included in which children and adolescents with ADHD were compared with their healthy peers in terms of gingival and/or periodontal endpoints. Bias appraisal was performed using the Joann Briggs tool for case-control and cross-sectional studies. Meta-analysis was performed using R language. Results are reported as mean difference (MD) and odds ratio (OR). Statistical analyses were performed in RStudio. RESULTS: A total of 149 records were identified in the searches. Seven studies were included. The meta-analysis showed that children and adolescents with ADHD had a higher mean gingival bleeding index (percentage) than their non-ADHD peers (MD = 11.25; CI = 0.08-22.41; I2 = 73%). There was no difference between groups for plaque index (MD = 4.87; CI = - 2.56 to 12.30; I2 = 63%) and gingivitis (OR = 1.42; CI = 0.22-9.21; I2 = 76%). Regarding the assessment of risk of bias, the major issue found in the articles was the absence of analyses for the control of confounding factors. CONCLUSION: Children and adolescents with ADHD had more gingival bleeding than their non-ADHD peers, but no difference regarding plaque or gingivitis was detected between groups. CLINICAL REGISTRATION: CRD42021258404.
BACKGROUND: This systematic review and meta-analysis aimed to answer the following question: Are children and adolescents with attention deficit hyperactivity disorder (ADHD) more likely to have gingival or periodontal disease-related outcomes than their non-ADHD peers? METHODS: Searches were conducted in the following databases: Embase, Scopus, Web of Science, and PubMed. Google Scholar and OpenGrey were also verified. Observational studies were included in which children and adolescents with ADHD were compared with their healthy peers in terms of gingival and/or periodontal endpoints. Bias appraisal was performed using the Joann Briggs tool for case-control and cross-sectional studies. Meta-analysis was performed using R language. Results are reported as mean difference (MD) and odds ratio (OR). Statistical analyses were performed in RStudio. RESULTS: A total of 149 records were identified in the searches. Seven studies were included. The meta-analysis showed that children and adolescents with ADHD had a higher mean gingival bleeding index (percentage) than their non-ADHD peers (MD = 11.25; CI = 0.08-22.41; I2 = 73%). There was no difference between groups for plaque index (MD = 4.87; CI = - 2.56 to 12.30; I2 = 63%) and gingivitis (OR = 1.42; CI = 0.22-9.21; I2 = 76%). Regarding the assessment of risk of bias, the major issue found in the articles was the absence of analyses for the control of confounding factors. CONCLUSION: Children and adolescents with ADHD had more gingival bleeding than their non-ADHD peers, but no difference regarding plaque or gingivitis was detected between groups. CLINICAL REGISTRATION: CRD42021258404.
Authors: Gilmar J Begnini; João A Brancher; Ana Tb Guimarães; Melissa R de Araujo; Eduardo Pizzatto Journal: Int J Clin Pediatr Dent Date: 2019 Nov-Dec
Authors: Katrin Bekes; Mike T John; Ksenija Rener-Sitar; Mohammad H Al-Harthy; Ambra Michelotti; Daniel R Reissmann; Julijana Nikolovska; Sahityaveera Sanivarapu; Folake B Lawal; Thomas List; Sanja Peršić Kiršić; Ljiljana Strajnić; Rodrigo Casassus; Kazuyoshi Baba; Martin Schimmel; Ama Amuasi; Ruwan D Jayasinghe; Sanela Strujić-Porović; Christopher C Peck; Han Xie; Karina Haugaard Bendixen; Miguel Angel Simancas-Pallares; Eka Perez-Franco; Mohammad Mehdi Naghibi Sistani; Patricia Valerio; Natalia Letunova; Nazik Nurelhuda; David W Bartlett; Ikeoluwa A Oluwafemi; Saloua Dghoughi; Joao N A R Ferreira; Pathamas Chantaracherd; Stella Sekulić Journal: Health Qual Life Outcomes Date: 2021-06-13 Impact factor: 3.186