Literature DB >> 35837025

An unusual case of appendicitis due to appendiceal neuroendocrine tumor in a patient: A case report.

Tingting Gao1, Weijue Xu1.   

Abstract

Appendiceal neuroendocrine tumor (NET) is the most common type of appendiceal cancer and is rare in the pediatric population. The clinical characteristics of this cancer are not specific and are highly similar to those of acute appendicitis. By contrast, acute appendicitis is a common surgical indication that is caused by obstruction of the appendix lumen. With a detection rate of 0.5-1% in all appendectomy specimens, appendiceal NET is rare histopathologically and can easily be missed. However, detecting an appendiceal NET in a patient with appendicitis is highly difficult. Therefore, clinicians must be aware of this much under-reported and rare tumor in children. In the present report, a case was reported, of a 13-year-old female child who initially presented with clinical presentation of acute appendicitis, but was subsequently diagnosed with appendiceal NET by histopathological examination after an emergency appendectomy. Follow-up examination including abdominal enhanced CT and enteroscopy 2 years after surgery revealed normal results. Copyright: © Gao et al.

Entities:  

Keywords:  appendiceal neuroendocrine tumor appendicitis; children

Year:  2022        PMID: 35837025      PMCID: PMC9257969          DOI: 10.3892/etm.2022.11458

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.751


  18 in total

Review 1.  Endocrine tumors of the appendix: a pathologic review.

Authors:  Lydia Deschamps; Anne Couvelard
Journal:  Arch Pathol Lab Med       Date:  2010-06       Impact factor: 5.534

Review 2.  Diagnosis and Treatment of Primary Tumors of the Appendix: a Critical Review.

Authors:  Andrea Ciarrocchi; Guido Rindi; Renato Pietroletti
Journal:  J Gastrointest Cancer       Date:  2021-03-19

3.  Retrospective evaluation of carcinoid tumors of the appendix in children.

Authors:  Rupert Prommegger; Peter Obrist; Christian Ensinger; Christoph Profanter; Reinhard Mittermair; Josef Hager
Journal:  World J Surg       Date:  2002-09-26       Impact factor: 3.352

4.  Neuroendocrine Tumor of the Appendix in Children.

Authors:  Hao Wu; Murali Chintagumpala; John Hicks; Jed G Nuchtern; M Fatih Okcu; Rajkumar Venkatramani
Journal:  J Pediatr Hematol Oncol       Date:  2017-03       Impact factor: 1.289

5.  Carcinoid tumors of the appendix in children: experience from a tertiary center in northern Greece.

Authors:  Emmanouil Hatzipantelis; Paraskevi Panagopoulou; Vasiliki Sidi-Fragandrea; Ioanna Fragandrea; Dimitrios E Koliouskas
Journal:  J Pediatr Gastroenterol Nutr       Date:  2010-11       Impact factor: 2.839

6.  Malignant neuroendocrine tumors: incidence and outcomes in pediatric patients.

Authors:  Bassan Allan; James Davis; Eduardo Perez; John Lew; Juan Sola
Journal:  Eur J Pediatr Surg       Date:  2013-02-26       Impact factor: 2.191

Review 7.  Recent Updates on Neuroendocrine Tumors From the Gastrointestinal and Pancreatobiliary Tracts.

Authors:  Joo Young Kim; Seung-Mo Hong
Journal:  Arch Pathol Lab Med       Date:  2016-05       Impact factor: 5.534

8.  Incidental carcinoid tumors of the appendix: do they affect presentation or prognosis?

Authors:  Jamie J Van Gompel; Emily Stoddard; Herbert Chen
Journal:  Int Surg       Date:  2007 Nov-Dec

9.  Surgical Management of Neuroendocrine Tumors of the Appendix in Children and Adolescents: A Retrospective French Multicenter Study of 114 Cases.

Authors:  Guénolée de Lambert; Hubert Lardy; Hélène Martelli; Daniel Orbach; Frédéric Gauthier; Florent Guérin
Journal:  Pediatr Blood Cancer       Date:  2015-12-10       Impact factor: 3.167

10.  Clinical validation of the gastrointestinal NET grading system: Ki67 index criteria of the WHO 2010 classification is appropriate to predict metastasis or recurrence.

Authors:  Takeshi Yamaguchi; Takahiro Fujimori; Shigeki Tomita; Kazuhito Ichikawa; Hiroyuki Mitomi; Kazuya Ohno; Yosuke Shida; Hiroyuki Kato
Journal:  Diagn Pathol       Date:  2013-04-22       Impact factor: 2.644

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