Qianli Liu1, Wenlin Wang2, Chun Hong1, Wei Liu1, Yang Liu2, Ziyin Shang1, Jing Tang1, Cuifen Liu1, Yingxing Liu1. 1. Department of Pediatric General Thoracic Surgery, Guangdong Women and Children Hospital Guangzhou 511442, Guangdong, China. 2. Department of Chest Wall Surgery, Guangdong Second People's Hospital Guangzhou 510317, Guangdong, China.
Abstract
OBJECTIVE: To observe the effects of minimally invasive surgical repair of pectus excavatum (NUSS) on the degree of chest flatness, cardiopulmonary function, and bone metabolism indexes in children of various age groups. METHODS: In this retrospective study, 62 children with pectus excavatum admitted to our hospital were divided into two groups: group A (3-12 years old) and group B (>12 years old), with 31 cases in each group. All of them were treated with NUSS. The treatment effectiveness, perioperative indexes (operation time, blood loss, ground time, and hospitalization time), degree of chest flatness, cardiopulmonary function, bone metabolism indicators, and complications were compared between the two groups. RESULTS: There was no significant difference between patients in the two groups in terms of operation time, blood loss, ground time, and hospitalization time (all P>0.05). The overall response rate to treatment in group A (93.55%) was higher than that of group B (70.97%; P<0.05). Three months after the operation, the chest flatness as well as serum alkaline phosphatase and its bone isoform levels in both groups were decreased, while left ventricular ejection fraction, cardiac index, stroke volume, FEV1, and peak expiratory flow levels were increased compared to before the operation, and the improvement in the above indicators of group A was better than Group B (all P<0.05). There was no significant difference in the incidence of complications between the two groups (16.13% vs. 9.68%; P>0.05). CONCLUSION: NUSS surgery can achieve satisfactory results in treating children with pectus excavatum at different ages. However, in a certain age range, a younger age indicates a better effect. NUSS procedure effectively improves postoperative flat chest, cardiopulmonary function, and bone metabolism indexes. AJTR
OBJECTIVE: To observe the effects of minimally invasive surgical repair of pectus excavatum (NUSS) on the degree of chest flatness, cardiopulmonary function, and bone metabolism indexes in children of various age groups. METHODS: In this retrospective study, 62 children with pectus excavatum admitted to our hospital were divided into two groups: group A (3-12 years old) and group B (>12 years old), with 31 cases in each group. All of them were treated with NUSS. The treatment effectiveness, perioperative indexes (operation time, blood loss, ground time, and hospitalization time), degree of chest flatness, cardiopulmonary function, bone metabolism indicators, and complications were compared between the two groups. RESULTS: There was no significant difference between patients in the two groups in terms of operation time, blood loss, ground time, and hospitalization time (all P>0.05). The overall response rate to treatment in group A (93.55%) was higher than that of group B (70.97%; P<0.05). Three months after the operation, the chest flatness as well as serum alkaline phosphatase and its bone isoform levels in both groups were decreased, while left ventricular ejection fraction, cardiac index, stroke volume, FEV1, and peak expiratory flow levels were increased compared to before the operation, and the improvement in the above indicators of group A was better than Group B (all P<0.05). There was no significant difference in the incidence of complications between the two groups (16.13% vs. 9.68%; P>0.05). CONCLUSION: NUSS surgery can achieve satisfactory results in treating children with pectus excavatum at different ages. However, in a certain age range, a younger age indicates a better effect. NUSS procedure effectively improves postoperative flat chest, cardiopulmonary function, and bone metabolism indexes. AJTR
Keywords:
Minimally invasive surgery of pectus excavatum; bone metabolism index; cardiopulmonary function; complications; different ages; the degree of flat chest
Authors: Wietse P Zuidema; Jan W A Oosterhuis; Stefan M van der Heide; Gerda W Zijp; Robertine van Baren; Alida F W van der Steeg; Ernst L W E van Heurn Journal: Eur J Cardiothorac Surg Date: 2019-04-01 Impact factor: 4.191
Authors: Dawn E Jaroszewski; Paul J Gustin; Frank-Martin Haecker; Hans Pilegaard; Hyung Joo Park; Shao-Tao Tang; Shuai Li; Li Yang; Sadashige Uemura; Jose Ribas Milanez De Campos; Robert Obermeyer; Frazier W Frantz; Michele Torre; Lisa McMahon; Andre Hebra; Chih-Chun Chu; J Duncan Phillips; David M Notrica; Antonio Messineo; Robert Kelly; Mustafa Yüksel Journal: Eur J Cardiothorac Surg Date: 2017-10-01 Impact factor: 4.191