Literature DB >> 35835874

Micromechanics of Biomembranes.

T Bhatia1.   

Abstract

Micromechanics techniques are playing an increasing role in characterization of biomembranes. The mechanical properties of membranes play an important role for a whole range of cellular processes. Lipid-protein biomembranes display lateral heterogeneity, domain formation, and morphological changes at mesoscopic and nanoscopic length scales. An attempt is made to introduce how membrane's material properties can be measured. Both fluctuation analysis and micro-pipette aspiration experiments have been used to quantify the micromechanics of membranes. The relationship between the structure and function of biomembranes is a critical concern in modern biology. This overview calls for a deeper understanding of how the cell complexity might be related to the mechanical properties of the lipid-protein membrane. Mechanical properties can influence cellular response to processes like adhesion, transport, differentiation, proliferation and migration.
© 2022. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Entities:  

Keywords:  Bending rigidity; GUVs; Lipid Membrane; Membrane organization; Membrane tension; Micromechanics

Year:  2022        PMID: 35835874     DOI: 10.1007/s00232-022-00254-w

Source DB:  PubMed          Journal:  J Membr Biol        ISSN: 0022-2631            Impact factor:   2.426


  51 in total

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Journal:  Q Rev Biophys       Date:  1991-08       Impact factor: 5.318

2.  Capturing suboptical dynamic structures in lipid bilayer patches formed from free-standing giant unilamellar vesicles.

Authors:  Tripta Bhatia; Flemming Cornelius; John H Ipsen
Journal:  Nat Protoc       Date:  2017-07-13       Impact factor: 13.491

3.  New biophysical methods to study the membrane activity of Bcl-2 proteins.

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Journal:  Methods Mol Biol       Date:  2014

4.  Membrane Nanotubes Increase the Robustness of Giant Vesicles.

Authors:  Tripta Bhatia; Jaime Agudo-Canalejo; Rumiana Dimova; Reinhard Lipowsky
Journal:  ACS Nano       Date:  2018-04-16       Impact factor: 15.881

5.  Simple sugars shape giant vesicles into multispheres with many membrane necks.

Authors:  Tripta Bhatia; Simon Christ; Jan Steinkühler; Rumiana Dimova; Reinhard Lipowsky
Journal:  Soft Matter       Date:  2020-01-08       Impact factor: 3.679

6.  Membrane shape modulates transmembrane protein distribution.

Authors:  Sophie Aimon; Andrew Callan-Jones; Alice Berthaud; Mathieu Pinot; Gilman E S Toombes; Patricia Bassereau
Journal:  Dev Cell       Date:  2014-01-27       Impact factor: 12.270

7.  Determination of bilayer membrane bending stiffness by tether formation from giant, thin-walled vesicles.

Authors:  L Bo; R E Waugh
Journal:  Biophys J       Date:  1989-03       Impact factor: 4.033

8.  Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles.

Authors:  Tobias Baumgart; Adam T Hammond; Prabuddha Sengupta; Samuel T Hess; David A Holowka; Barbara A Baird; Watt W Webb
Journal:  Proc Natl Acad Sci U S A       Date:  2007-02-21       Impact factor: 11.205

9.  RELATION BETWEEN WATER PERMEABILITY AND INTEGRITY OF SULFHYDRYL GROUPS IN MALIGNANT AND NORMAL CELLS.

Authors:  M Belkin; W G Hardy
Journal:  J Biophys Biochem Cytol       Date:  1961-04-01
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