BACKGROUND: This retrospective observational study aimed to evaluate the impact of sarcopenia on surgical site infection (SSI) risk in patients who undergo posterior lumbar fusion. While many studies have investigated the impact of sarcopenia on postoperative morbidity both in general and orthopedic surgery, none of them examined the risk of postoperative infection after lumbar spine surgery in sarcopenic vs nonsarcopenic patients. METHODS: Consecutive 55- to 75-year-old patients who underwent short posterior lumbar fusion for degenerative pathology between 2004 and 2019 were included. Charts were reviewed, and the psoas:lumbar vertebral index (PLVI) was used as a measure of central sarcopenia. Patients were stratified according to low vs high PLVI and then according to postoperative infection status. SSI was assessed as an outcome. A statistical analysis was performed to identify risk factors for infection. RESULTS: A total of 304 patients were included; 24 (7.9%) developed postoperative SSI. The average follow-up was 26.2 months. The sarcopenic group was found to not have a higher likelihood of experiencing postoperative SSI (P = 0.947). Only Charlson Comorbidity Index and American Society of Anesthesiology score were significantly associated with infectious complications (P = 0.008 and P = 0.017, respectively). CONCLUSIONS: Low PLVI was not associated with postoperative SSI in this study. This finding is in contrast with the findings of other authors who found sarcopenia to be a risk factor for postoperative complications. However, these studies did not consider SSI as the only primary endpoint, and patients were not stratified by indication (degeneration, infection, tumor, and trauma) or surgical procedure. CLINICAL RELEVANCE: Low PLVI was not associated with postoperative SSI in patients who undergo short posterior lumbar fusion for degenerative pathology. This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery.
BACKGROUND: This retrospective observational study aimed to evaluate the impact of sarcopenia on surgical site infection (SSI) risk in patients who undergo posterior lumbar fusion. While many studies have investigated the impact of sarcopenia on postoperative morbidity both in general and orthopedic surgery, none of them examined the risk of postoperative infection after lumbar spine surgery in sarcopenic vs nonsarcopenic patients. METHODS: Consecutive 55- to 75-year-old patients who underwent short posterior lumbar fusion for degenerative pathology between 2004 and 2019 were included. Charts were reviewed, and the psoas:lumbar vertebral index (PLVI) was used as a measure of central sarcopenia. Patients were stratified according to low vs high PLVI and then according to postoperative infection status. SSI was assessed as an outcome. A statistical analysis was performed to identify risk factors for infection. RESULTS: A total of 304 patients were included; 24 (7.9%) developed postoperative SSI. The average follow-up was 26.2 months. The sarcopenic group was found to not have a higher likelihood of experiencing postoperative SSI (P = 0.947). Only Charlson Comorbidity Index and American Society of Anesthesiology score were significantly associated with infectious complications (P = 0.008 and P = 0.017, respectively). CONCLUSIONS: Low PLVI was not associated with postoperative SSI in this study. This finding is in contrast with the findings of other authors who found sarcopenia to be a risk factor for postoperative complications. However, these studies did not consider SSI as the only primary endpoint, and patients were not stratified by indication (degeneration, infection, tumor, and trauma) or surgical procedure. CLINICAL RELEVANCE: Low PLVI was not associated with postoperative SSI in patients who undergo short posterior lumbar fusion for degenerative pathology. This manuscript is generously published free of charge by ISASS, the International Society for the Advancement of Spine Surgery.
Authors: Tom A Ranger; Flavia M Cicuttini; Tue S Jensen; Waruna L Peiris; Sultana Monira Hussain; Jessica Fairley; Donna M Urquhart Journal: Spine J Date: 2017-07-26 Impact factor: 4.166
Authors: Alfonso J Cruz-Jentoft; Gülistan Bahat; Jürgen Bauer; Yves Boirie; Olivier Bruyère; Tommy Cederholm; Cyrus Cooper; Francesco Landi; Yves Rolland; Avan Aihie Sayer; Stéphane M Schneider; Cornel C Sieber; Eva Topinkova; Maurits Vandewoude; Marjolein Visser; Mauro Zamboni Journal: Age Ageing Date: 2019-01-01 Impact factor: 10.668
Authors: Alfonso J Cruz-Jentoft; Francesco Landi; Stéphane M Schneider; Clemente Zúñiga; Hidenori Arai; Yves Boirie; Liang-Kung Chen; Roger A Fielding; Finbarr C Martin; Jean-Pierre Michel; Cornel Sieber; Jeffrey R Stout; Stephanie A Studenski; Bruno Vellas; Jean Woo; Mauro Zamboni; Tommy Cederholm Journal: Age Ageing Date: 2014-09-21 Impact factor: 10.668