| Literature DB >> 35835524 |
Verity Frances Todd1,2, Melanie Moylan3, Graham Howie4,2, Andy Swain2,5, Aroha Brett4, Tony Smith4, Bridget Dicker4,2.
Abstract
OBJECTIVES: The utility of New Zealand Early Warning Score (NZEWS) for prediction of adversity in low-acuity patients discharged at scene by paramedics has not been investigated. The objective of this study was to evaluate the association between the NZEWS risk-assessment tool and adverse outcomes of early mortality or ambulance reattendance within 48 hours in low-acuity, prehospital patients not transported by ambulance.Entities:
Keywords: ACCIDENT & EMERGENCY MEDICINE; EPIDEMIOLOGY; Protocols & guidelines
Mesh:
Year: 2022 PMID: 35835524 PMCID: PMC9289032 DOI: 10.1136/bmjopen-2021-058462
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 3.006
Figure 1Inclusion and exclusion criteria for the cases included in the New Zealand Early Warning Score (NZEWS) analysis. EMS, emergency medical service.
Figure 2The distribution of prehospital New Zealand Early Warning Score (NZEWS) values and NZEWS colour groupings in low-acuity adult patients discharged at scene. The number of patients with each total NZEWS is shown. Patients with an NZEWS>16 were consolidated. Most patients presented with low NZEWS and grouped within the white and yellow risk groups.
Characteristics of low-acuity discharged-at-scene adult patients with and without sufficient information to calculate a New Zealand Early Warning Score
| Variable | Variable category | All discharged-at-scene adults | Discharged-at-scene adults without a calculable EWS (<7 vital signs recorded) | Discharged-at-scene adults with calculable EWS (7 vital signs recorded) |
| 71 580 | 30 174 (42.2%) | 41 406 (57.8%) | ||
| Age, mean±SD | 57.57±24.54 | 54.84±24.97 | 59.55±24.03 | |
| Sex | Male | 31 356 (43.8%) | 13 668 (45.3%) | 17 688 (42.7%) |
| Female | 40 178 (56.2%) | 16 481 (54.7%) | 23 697 (57.3%) | |
| Ethnicity | European/other | 52 339 (73.1%) | 21 887 (72.6%) | 30 452 (73.6%) |
| Māori | 11 186 (15.6%) | 5090 (16.9%) | 6096 (14.7%) | |
| Pacific peoples | 4451 (6.2%) | 1661 (5.5%) | 2790 (6.7%) | |
| Asian | 3584 (5.0%) | 1530 (5.1%) | 2054 (5.0%) | |
| Deprivation | Quintile 1 (least deprived) | 9470 (13.6%) | 3879 (13.3%) | 5591 (13.9%) |
| Quintile 2 | 10 603 (15.3%) | 4452 (15.2%) | 6151 (15.3%) | |
| Quintile 3 | 12 837 (18.5%) | 5351 (18.3%) | 7486 (18.6%) | |
| Quintile 4 | 16 222 (23.4%) | 6900 (23.6%) | 9322 (23.2%) | |
| Quintile 5 (most deprived) | 20 287 (29.2%) | 8622 (29.5%) | 11 665 (29.0%) | |
| Urban versus rural | Rural | 16 438 (23.4%) | 6436 (21.9%) | 10 002 (24.5%) |
| Urban | 53 771 (76.6%) | 23 011 (78.1%) | 30 760 (75.5%) | |
| Adverse outcome | 48-hour ambulance reattendance | 3764 (5.3%) | 1460 (4.8%) | 2304 (5.6%) |
| 2-day mortality | 180 (0.3%) | 69 (0.2%) | 111 (0.3%) | |
| 7-day mortality | 413 (0.6%) | 158 (0.5%) | 255 (0.6%) | |
| 30-day mortality | 1214 (1.7%) | 444 (1.5%) | 770 (1.9%) | |
| Respiration rate, median, IQR | 16, 16–18 | 16, 16–18 | 16, 16–18 | |
| Oxygen saturation, median, IQR (%) | 98, 97–99 | 98, 97–99 | 98, 97–99 | |
| Use of supplemental oxygen (%) | No | 71 092 (99.3%) | 30 086 (99.7%) | 41 006 (99.0%) |
| Yes | 488 (0.7%) | 88 (0.3%) | 400 (1.0%) | |
| Temperature, median, IQR | 36.6, 36.2–37.0 | 36.6, 36.1–37.0 | 36.6, 36.2–37.0 | |
| Systolic blood pressure, median, IQR | 137, 122–150 | 138, 122–150 | 136, 122–150 | |
| Heart rate, median, IQR | 80, 70–90 | 80, 70–89 | 80, 70–90 | |
| Level of Consciousness (AVPU) | Alert | 70 470 (98.4%) | 29 672 (98.3%) | 40 798 (98.5%) |
| Not Alert | 1110 (1.6%) | 502 (1.7%) | 608 (1.5%) |
Missing values did not exceed 5% for any variable.
AVPU, alert, voice, pain, unresponsive; early warning score, EWS.
Descriptive analysis and associations between New Zealand Early Warning Score (NZEWS) and adverse outcomes in low-acuity patients not transported by ambulance
| NZEWS colours | Total | 48-hour ambulance reattendance | 2-day mortality | 7-day mortality | 30-day mortality | Adjusted ORs | |||
| 48-hour ambulance reattendance | 2-day mortality | 7-day mortality | 30-day mortality | ||||||
| (NZEWS total) | n (%) | n (%) | n (%) | n (%) | n (%) | AOR (95% CI) | AOR (95% CI) | AOR (95% CI) | AOR (95% CI) |
| White (0) (ref) | 20 438 (49.4) | 1011 (4.9) | 11 (0.1) | 38 (0.2) | 178 (0.9) | 1.00* | 1.00* | 1.00* | 1.00* |
| Yellow (1–5) | 18 615 (45.0) | 1089 (5.9) | 55 (0.3) | 126 (0.7) | 403 (2.2) | 1.23 (1.12 to 1.34) | 5.62 (2.94 to 10.75) | 3.89 (2.70 to 5.62) | 2.60 (2.17 to 3.11) |
| Orange (6–7) | 59 (0.1) | 5 (8.5) | 0 (0) | 1 (1.7) | 4 (6.8) | 1.64 (0.65 to 4.15) | 8.24 (1.10 to 61.55) | 7.37 (2.60 to 20.87) | |
| Red (8–9 or any vital sign in red zone) | 1956 (4.7) | 171 (8.7) | 33 (1.7) | 69 (3.5) | 155 (7.9) | 1.76 (1.48 to 2.09) | 28.57 (14.36 to 56.81) | 18.55 (12.36 to 27.83) | 9.28 (7.39 to 11.65) |
| Blue (10+ or any vital sign in blue zone) | 338 (0.8) | 28 (8.3) | 12 (3.6) | 21 (6.2) | 30 (8.9) | 1.79 (1.20 to 2.68) | 70.64 (30.73 to 162.36) | 38.45 (22.04 to 67.09) | 12.27 (8.09 to 18.30) |
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Adjusted for age, sex, ethnicity, deprivation and NZEWS; ref—reference group. All columns were significant with respect to the reference group.
*P value<0.001.
AOR, adjusted OR.
Area under the receiving operating curve (AUROC), cut-off values, sensitivity, specificity and Youden’s Index for each adverse outcome for the aggregate New Zealand Early Warning Score (NZEWS)
| Adverse outcome | AUROC result | Cut-off value | Sensitivity | Specificity | Youden’s Index |
| 48-hour reattendance | 0.55 (0.53 to 0.56) | 1.50 (NZEWS≥2) | 0.29 | 0.78 | 0.07 |
| 2-day mortality | 0.82 (0.78 to 0.86) | 1.50 (NZEWS≥2) | 0.76 | 0.78 | 0.54 |
| 7-day mortality | 0.78 (0.75 to 0.81) | 1.50 (NZEWS≥2) | 0.68 | 0.78 | 0.46 |
| 30-day mortality | 0.70 (0.68 to 0.73) | 1.50 (NZEWS≥2) | 0.55 | 0.79 | 0.34 |