Literature DB >> 35832946

Cerebellopontine Angle Epidermoids: Comparative Results of Microscopic and Endoscopic Excision Using the Retromastoid Approach".

Suyash Singh1, Kuntal Kanti Das1, Krishna Kumar1, Kamlesh Rangari1, Priyadarshi Dikshit1, Kamlesh Singh Bhaisora1, Jayesh Sardhara1, Anant Mehrotra1, Arun Kumar Srivastava1, Awadhesh Kumar Jaiswal1, Sanjay Behari1.   

Abstract

Background  Densely packed neurovascular structures, often times inseparable capsular adhesions and sometimes a multicompartmental tumor extension, make surgical excision of cerebellopontine angle epidermoids (CPEs) a challenging task. A simultaneous or an exclusive endoscopic visualization has added a new dimension to the classical microscopic approaches to these tumors recently. Methods  Eighty-six patients (age: 31.6 ± 11.7 years, M:F = 1:1) were included. Nineteen patients (22.1%) had a multicompartmental tumor. Tumor extension was classified into five subtypes. Sixty-two patients underwent a pure microscopic approach (72%) out of which 10 patients (16%) underwent an endoscope-assisted surgery (11.6%) and 24 patients (28%) underwent an endoscope-controlled excision. Surgical outcomes were retrospectively analyzed. Results  Headache (53.4%), hearing loss (46.5%), and trigeminal neuralgia (41.8%) were the leading symptoms. Interestingly, 21% of the patients had at least one preexisting cranial nerve deficit. Endoscopic assistance helped in removing an unseen tumor lobule in 3 of 10 patients (30%). Pure endoscopic approach significantly reduced the hospital stay from 9.2 to 7.3 days ( p  = 0.012), and had a statistically insignificant yet a clearly noticeable lesser incidence of subtotal tumor excision (0 vs. 10%, p  = 0.18) with comparable cranial nerve deficits but with a higher postoperative cerebrospinal fluid (CSF) leak rate (29% vs. 4.8%, p  = 0.004). Conclusion  Endoscope assistance in CPE surgery is a useful addition to conventional microscopic retromastoid approach. Pure endoscopic excision in CPE is feasible, associated with a lesser duration of hospital stay, better extent of excision in selected cases, and it has a comparable cranial nerve morbidity profile albeit with a higher rate of CSF leak. Thieme. All rights reserved.

Entities:  

Keywords:  cerebellopontine angle; cisterns; classification; complications; endoscopy; epidermoid; microsurgery; multicompartmental

Year:  2021        PMID: 35832946      PMCID: PMC9272261          DOI: 10.1055/s-0040-1722713

Source DB:  PubMed          Journal:  J Neurol Surg B Skull Base        ISSN: 2193-634X


  23 in total

1.  Transpetrosal approaches to the posterior fossa.

Authors:  Ramachandra P Tummala; Ernesto Coscarella; Jacques J Morcos
Journal:  Neurosurg Focus       Date:  2005-08-15       Impact factor: 4.047

2.  Evolution of epidermoid cyst into dermoid cyst: Embryological explanation and radiological-pathological correlation.

Authors:  Parthiban Balasundaram; Ajay Garg; Anuj Prabhakar; Leve S Joseph Devarajan; Shailesh B Gaikwad; Gaurav Khanna
Journal:  Neuroradiol J       Date:  2019-01-03

3.  Microneurosurgical treatment of intracranial dermoid and epidermoid tumors.

Authors:  M G Yaşargil; C D Abernathey; A C Sarioglu
Journal:  Neurosurgery       Date:  1989-04       Impact factor: 4.654

4.  Pure endoscopic removal of epidermoid tumors of the cerebellopontine angle.

Authors:  Yuping Peng; Lei Yu; Yu Li; Jun Fan; Mingxing Qiu; Songtao Qi
Journal:  Childs Nerv Syst       Date:  2014-01-31       Impact factor: 1.475

5.  Giant intracranial epidermoids: is total removal feasible?

Authors:  Emad Aboud; Mohammad Abolfotoh; Svetlana Pravdenkova; Abdulkerim Gokoglu; Murat Gokden; Ossama Al-Mefty
Journal:  J Neurosurg       Date:  2015-01-16       Impact factor: 5.115

6.  Combined Transpetrosal Approach With Preservation of Superior Petrosal Vein Drainage for a Cerebellopontine Angle Epidermoid Cyst Extending Into Meckel's Cave: 3-Dimensional Operative Video.

Authors:  Ken Matsushima; Michihiro Kohno; Nobuyuki Nakajima; Norio Ichimasu
Journal:  Oper Neurosurg (Hagerstown)       Date:  2019-06-01       Impact factor: 2.703

7.  Endoscope-assisted microsurgical resection of epidermoid tumors of the cerebellopontine angle.

Authors:  Henry W S Schroeder; Joachim Oertel; Michael R Gaab
Journal:  J Neurosurg       Date:  2004-08       Impact factor: 5.115

8.  Intracranial epidermoid tumor; microneurosurgical management: An experience of 23 cases.

Authors:  Forhad Hossain Chowdhury; Mohammod Raziul Haque; Mainul Haque Sarker
Journal:  Asian J Neurosurg       Date:  2013-01

Review 9.  Repeated recurrent epidermoid cyst with atypical hyperplasia: A case report and literature review.

Authors:  Jialin Li; Ming Qian; Xiaoyi Huang; Li Zhao; Xinghai Yang; Jianru Xiao
Journal:  Medicine (Baltimore)       Date:  2017-12       Impact factor: 1.817

10.  Endoscopic Assisted Retrosigmoid Approach for Cerebellopontine Angle Epidermoid Tumor.

Authors:  Katherine Kunigelis; Alexander Yang; A Samy Youssef
Journal:  J Neurol Surg B Skull Base       Date:  2018-09-25
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