| Literature DB >> 35829831 |
Ke-Ru Li1,2,3, An-Guo Wu2,4, Yong Tang2, Xiao-Peng He5, Chong-Lin Yu1, Jian-Ming Wu2,4, Guang-Qiang Hu6, Lu Yu7,8,9.
Abstract
Neurodegenerative diseases (NDs), including chronic disease such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and multiple sclerosis, and acute diseases like traumatic brain injury and ischemic stroke are characterized by progressive degeneration, brain tissue damage and loss of neurons, accompanied by behavioral and cognitive dysfunctions. So far, there are no complete cures for NDs; thus, early and timely diagnoses are essential and beneficial to patients' treatment. Magnetic resonance imaging (MRI) has become one of the advanced medical imaging techniques widely used in the clinical examination of NDs due to its non-invasive diagnostic value. In this review, research published in English in current decade from PubMed electronic database on the use of MRI to detect specific biomarkers of NDs was collected, summarized, and discussed, which provides valuable suggestions for the early diagnosis, prevention, and treatment of NDs in the clinic.Entities:
Keywords: Alzheimer’s disease; Biomarkers; Diagnosis; Huntington’s disease; Magnetic resonance imaging; Neurodegenerative diseases; Parkinson’s disease; Positron emission computed tomography
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Year: 2022 PMID： 35829831 DOI： 10.1007/s12035-022-02944-x
Source DB: PubMed Journal: Mol Neurobiol ISSN： 0893-7648 Impact factor: 5.682